Zdravljenje revmatoidnega artritisa s kortikosteroidi; Corticosteroid treatment of rheumathoid arthritis

Faculty of Pharmacy, Lj. (FFALJ)

Zdravljenje revmatoidnega artritisa s kortikosteroidi = Corticosteroid treatment of rheumathoid arthritis

Božič, Borut ; Rozman, Blaž

Revmatoidni artritis (RA) je kronična vnetna revmatična bolezen avtoimunske narave. Večinoma poteka kot sklepno obolenje, redkeje je sklepom pridružena tudi prizadetost drugih organov-tedaj govorimo ... o sistemski obliki bolezni. Za bolezen, za katero moramo predvideti večdesetletno strategijo zdravljenja, danes velja sledeče osnovno pravilo: poleg fizioterapije, analgetikov in nesteroidnih antirevmatikov, se uporablja enega ali več zdravil, ki modificirajo potek bolezni (DMARD), občasno lahko tudi skupaj s kortikosteroidi (KS), vendar večina bolnikov z RA ne potrebuje niti sistemskega, niti lokalnega zdravljenja s KS. Endogeni KS so fiziološko pomembni hormoni in pri njihovi uporabi v zdravljenju moramo to upoštevati. Novejši koncepti povezujejo kortikosteroidno delovanje na stres z njihovim učinkom biološke nagrade. Njihovo genomsko (inhibicija ali stimulacija genskega prepisa) in negenomsko (receptorsko posredovano in fizikalno kemijsko) delovanje na vnetje in celični cikel uporabljamo pri zdravljenju bolnikov z RA.

Source: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Let. 50, št. 3, 1999, str. 393-398)

Type of material - article, component part

Publish date - 1999

Language - slovenian

COBISS.SI-ID - 587889

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Topics
revmatoidni artritis | zdravljenje | kortikosteroidi

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source: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Let. 50, št. 3, 1999, str. 393-398)

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Year	Impact factor		Edition		Category		Classification
Year	JCR	SNIP	JCR	SNIP	JCR	SNIP	JCR	SNIP

Links to authors' personal bibliographies	Links to information on researchers in the SICRIS system
Božič, Borut	00781
Rozman, Blaž	07180

Source: Personal bibliographies and: SICRIS

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