Faculty of Pharmacy, Lj. (FFALJ)
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Zdravljenje revmatoidnega artritisa s kortikosteroidi = Corticosteroid treatment of rheumathoid arthritisBožič, Borut ; Rozman, BlažRevmatoidni artritis (RA) je kronična vnetna revmatična bolezen avtoimunske narave. Večinoma poteka kot sklepno obolenje, redkeje je sklepom pridružena tudi prizadetost drugih organov-tedaj govorimo ... o sistemski obliki bolezni. Za bolezen, za katero moramo predvideti večdesetletno strategijo zdravljenja, danes velja sledeče osnovno pravilo: poleg fizioterapije, analgetikov in nesteroidnih antirevmatikov, se uporablja enega ali več zdravil, ki modificirajo potek bolezni (DMARD), občasno lahko tudi skupaj s kortikosteroidi (KS), vendar večina bolnikov z RA ne potrebuje niti sistemskega, niti lokalnega zdravljenja s KS. Endogeni KS so fiziološko pomembni hormoni in pri njihovi uporabi v zdravljenju moramo to upoštevati. Novejši koncepti povezujejo kortikosteroidno delovanje na stres z njihovim učinkom biološke nagrade. Njihovo genomsko (inhibicija ali stimulacija genskega prepisa) in negenomsko (receptorsko posredovano in fizikalno kemijsko) delovanje na vnetje in celični cikel uporabljamo pri zdravljenju bolnikov z RA.Source: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Let. 50, št. 3, 1999, str. 393-398)Type of material - article, component partPublish date - 1999Language - slovenianCOBISS.SI-ID - 587889
Author
Božič, Borut |
Rozman, Blaž
Topics
revmatoidni artritis |
zdravljenje |
kortikosteroidi
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source: Farmacevtski vestnik : strokovno glasilo slovenske farmacije = pharmaceutical journal of Slovenia. - ISSN 0014-8229 (Let. 50, št. 3, 1999, str. 393-398)
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Database name | Field | Year |
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Božič, Borut | 00781 |
Rozman, Blaž | 07180 |
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