Introduction: In Croatia, about 3,500 patients are diagnosed with a colorectal carcinoma annually. The National Program for Early Detection of Colon Cancer has been implemented in Croatia since 2007. ...The program’s primary goal is todetect colon cancer at an early stage of the disease, which should reduce the incidence and mortality from colon cancer. Aim: To determine the interest of the target group in participating in the program, reasons for not responding to the program, and their knowledge about it altogether. Materials and methods: Surveying 50 patients within the program’s target group about their response to and understanding of reasons for screening. Results: Although 84% of the participants know about the program, the response rate was unsatisfactory. Conclusion: Most of the respondents who suffered from a colorectal carcinoma received a call but did not respond due to the absence of symptoms, which correlates with a low level of knowledge on colorectal carcinoma.
Aim. A retrospective study of the occurrence of liver damage and obstetric outcomes in pregnant women diagnosed with pruritus. Methods. The following parameters were monitored in patients: aspartate ...aminotransferase (AST), alanine aminotransferase, gamma-glutamyl transferase, bilirubin (direct and total), hemoglobin, platelets, serum bile acid level, age of pregnant women, parity, pregnancy weight gain, birth weight, and gestational age at delivery. A total of 107 patients were included during a five-year period (2016–2020) and classified into three groups. Group A included 17 pregnant women with pruritus without elevated liver enzymes and bilirubin. Group B included 50 pregnant women with pruritus, elevated liver enzymes, and bilirubin. Group C included 40 pregnant women with pruritus and elevated bile acids (regardless of liver enzyme levels). Results. The groups did not significantly differ in patients’ age and parity, but there was a statistically significant between-group difference in weight gain during pregnancy. The values of AST, ALT, GGT, LDH, and direct bilirubin were the highest in group B, and serum bile acids were expectedly the highest in group C. There was no statistically significant variation in the onset of labor and mode of delivery between groups. However, groups significantly differed in gestational age at delivery, newborn birthweight, and pregnancy prolongation from the onset of pruritus to delivery. Conclusion. Further study is needed to assess the pathophysiologic mechanisms underlying intrahepatic cholestasis of pregnancy as well as any significant liver damage associated with pregnancy.
Sweetov sindrom Bebek, Jana; Baković, Drago; Bebek, Mara ...
Liječnički vjesnik,
12/2022, Volume:
144, Issue:
Supp 6
Web Resource
Open access
Sweetov sindrom (SS) ili akutna febrilna neutrofilna dermatoza, rijedak je kožni poremećaj kojeg karakterizira bolan kožni osip po licu, vratu i gornjim ekstremitetima uz vrućicu. Patogeneza ...Sweetovog sindroma nije poznata, no pojava bolesti povezuje se s infekcijama, nekim lijekovima, paraneoplastičnim i upalnim zbivanjima.
Uvod: Godišnje u Hrvatskoj od kolorektalnog karcinoma oboli oko 3500 bolesnika. Nacionalni program ranog otkrivanja raka debelog crijeva u Hrvatskoj se provodi od 2007. godine. Primarni cilj programa ...je otkrivanje raka debelog crijeva u ranoj fazi bolesti, što bi trebalo smanjiti učestalost i smrtnost od raka debelog crijeva.
Cilj: Utvrditi interes ciljne skupine za sudjelovanje u programu, razloge neodazivanja na program te njihovu ukupnu upućenost u program.
Materijali i metode: Anketiranje 50 pacijenata unutar ciljne skupine programa o njihovom odgovoru i razumijevanju razloga za probir.
Rezultati: Iako 84% sudionika zna za program, stopa odaziva nije bila zadovoljavajuća.
Zaključak: Većina ispitanika koji su bolovali od kolorektalnog karcinoma primili su poziv, ali se nisu odazvali zbog nepostojanja simptoma, što korelira s niskom razinom znanja o kolorektalnom karcinomu.