For 9-12% Cr creep-resistant steels, a new kind of replica, contemporaneously morphological and extractive, is nowadays in use. This method is non-destructive and 'in situ' applicable via a ...customised portable equipment and allows the study of the steel microstructure evolution during in-service inspections. The technique produces a neat imprint of the steel microstructure, like a morphological replica, but contemporaneously extracts particles down to 15-20 nm diameters. The use of a good electrical conductor extraneous to the steel composition as a replication basis allows the investigation of the martensitic (sub-) microstructure together with the particle distribution, nanometric dimensional and chemical analyses using a tungsten electrode scanning electron microscope at magnifications up to 500000×. For component residual life assessment, besides a measuring technique and a damage witnessing criterion, a reference is needed against which spent lifetime through which or actual damage can be estimated. .
Aims: To determine in a case-control study possible associations between the development of acute renal failure in preterm newborns and therapeutic interventions, particularly drug treatments. ...Methods: The study population was 172 preterm infants of <38 weeks gestation; 71 had acute renal failure and 101 were controls closely matched for gestational age and birth weight. Maternal and neonatal information was collected for both groups through questionnaires and interviews. Routine data on renal variables were also collected. Univariate and multivariate logistic regression analyses were performed. Results: Very low birthweight infants were at high risk of acute renal failure (79% of cases were <1500 g). However, the acute renal failure was transient. Mothers of infants with acute renal failure received more drugs during pregnancy and delivery (mainly antibiotics and non-steroidal anti-inflammatory drugs). Of the possible therapeutic interventions, intubation, catheterisation, and phototherapy were mainly applied to case subjects. A low Apgar score and patent ductus arteriosus were diagnosed in a greater percentage of neonates with acute renal failure. Moreover, in the first few days of life and before diagnosis of acute renal failure, case subjects received more drugs (antibiotics, non-steroidal anti-inflammatory drugs, and diuretics) and for a longer time. In the multivariate logistic analysis, medullary hyperechogenicity (odds ratio (OR) 4.491; 95% confidence interval (CI) 1.879 to 10.731) and ceftazidime administration (OR 5.082; 95% CI 1.493 to 17.297) were associated with a greater risk of acute renal failure. Conclusions: The results suggest the need for careful monitoring of very low birthweight infants and attention to drug treatments, as it is difficult to differentiate between normality and renal failure in the first few days of life.
Delayed Information Processing Speed (IPS) often underlies attention deficits and is particularly evident in patients with traumatic brain injury, Parkinson's disease, depression, dementia, and ...multiple sclerosis. Therefore, it is of interest to determine the brain network that is responsible for such essential cognitive function to understand IPS deficits and to develop effective rehabilitation programs. We assessed brain functional connectivity and effective connectivity during the performance of an adapted version of the Symbol Digit Modalities Test. Using dynamic causal modeling, we focused on obtaining a network model for IPS function in healthy subjects. Sixteen right-handed volunteers (seven women, age: 29.7 ± 5.0 years) were included in the study after giving written consent for participating. Functional magnetic resonance images were acquired in a 3T scanner. According to our results, two systems interact during the IPS task performance. One is formed by frontoparietal and fronto-occipital networks, related to the control of goal-directed (top-down) selection for stimuli and response, while the second is composed of the temporoparietal and inferior frontal cortices, which are associated with stimulus-driven attention in the brain. Additionally, the default-mode network showed a significant correlation with networks positively associated with the task, mainly those related to visual detection and processing, indicating its relevant role in functional integration involving IPS. Therefore, an IPS-related network was proposed through a methodology that may be useful for future studies considering other cognitive functions and tasks, clinical groups, and longitudinal assessments.
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Status of the SPES Exotic Beam Facility Comunian, M; Andrighetto, A; Antonini, P ...
Journal of physics. Conference series,
01/2020, Volume:
1401, Issue:
1
Journal Article
Peer reviewed
Open access
At Legnaro National Laboratories of INFN is under construction a Rare Isotope Facility called "Selective Production of Exotic Species" (SPES) based on a 35-70 MeV proton cyclotron, able to deliver ...two beams with a total current up to 0.75 mA, an ISOL fission target station and an existing ALPI superconducting accelerator as a post accelerator (up to 10 MeV/u for A/q=7). The paper will cover notably: the high-resolution mass separator, the CW RFQ (80 MHz, 727 keV/u, with internal bunching), the 1+ low energy transfer line and the injection line from Charge Breeder to ALPI under installation.
SPES (Selective Production of Exotic Species) is an ISOL type facility for production and post-acceleration of exotic nuclei for forefront research in nuclear physics. Radioactive (RA) species (A = ...80÷160) will be produced by fissions induced by a proton beam impinging on an UCx target: the proton beam will be delivered by a commercial cyclotron with a 40 MeV maximum energy and a 0.25 mA maximum current. The RA species, extracted from the Target-Ion-Source system as a 1+ beam, will be cooled in a RFQ (radiofrequency quadrupole) beam cooler (RFQ-BC) and purified from the isobars contaminants through a High Resolution Mass Separator (HRMS). Post-acceleration will be performed via an ECR-based charge breeder, delivering the obtained q+ RA beam to a being built CW RFQ and to the being upgraded superconducting (sc) linac ALPI (up to 10 MeV/A for a mass-to-charge ratio A/q = 7).
A new Radioactive Ion Beam (RIB) facility (SPES) is presently under construction at the Legnaro National Laboratories of INFN. The SPES facility is based on the ISOL method using an UCx Direct Target ...able to sustain a power of 8 kW. The primary proton beam is provided by a high current Cyclotron accelerator with energy of 35-70 MeV and a beam current of 0.2-0.7 mA. Neutron-rich radioactive ions are produced by proton induced fission on an Uranium target at an expected fission rate of the order of 1013 fissions per second. After ionization and selection the exotic isotopes are re-accelerated by the ALPI superconducting LINAC at energies of 10A MeV for masses in the region A=130 amu. The expected secondary beam rates are of the order of 107 - 109 pps. Aim of the SPES facility is to deliver high intensity radioactive ion beams of neutron rich nuclei for nuclear physics research as well as to be an interdisciplinary research centre for radio-isotopes production for medicine and for neutron beams.
The SPES Radioactive Ion Beam (RIB) facility at INFN-LNL is in the construction phase. It is based on the ISOL method with an UCx Direct Target able to sustain a power of 10 kW. The primary proton ...beam is delivered by a high current Cyclotron accelerator, with energy 35-70 MeV and a beam current of 0.2-0.5 mA. Neutron-rich radioactive ions will be produced by proton induced Uranium fission in the UCx target at an expected fission rate in the order of 10 super(13) fissions per second. The exotic isotopes will be re-accelerated by the ALPI superconducting LINAC at energies of 10A MeV and higher, for masses in the region A=130 amu at expected rate on the secondary target of 10 super(7) - 10 super(9) pps. The SPES project has the aim to provide high intensity and high-quality beams of neutron-rich nuclei as well as to develop an interdisciplinary research center based on the cyclotron proton beam.
The SPES Radioactive Ion Beam facility of INFN de Angelis, G; Prete, G; Andrighetto, A ...
Journal of physics. Conference series,
02/2015, Volume:
580, Issue:
1
Journal Article, Conference Proceeding
Peer reviewed
Open access
A new Radioactive Ion Beam (RIB) facility (SPES) is presently under construction at the Legnaro National Laboratories of INFN. The SPES facility is based on the ISOL method using an UCx Direct Target ...able to sustain a power of 10 kW. The primary proton beam is provided by a high current Cyclotron accelerator with energy of 40 MeV and a beam current of 0.2-0.5 mA. Neutron-rich radioactive ions are produced by proton induced fission at an expected fission rate of the order of 1013 fissions per second. After ionization and selection the exotic isotopes are re-accelerated by the ALPI superconducting LINAC at energies of 10A MeV for masses in the region A=130 amu. The expected secondary beam rates are of the order of 107 – 109 pps. Aim of the SPES facility is to deliver high intensity radioactive ion beams of neutron rich nuclei for nuclear physics research as well as to be an interdisciplinary research center for radio-isotopes production for medicine and for neutron beams.
A new Radioactive Ion Beam (RIB) facility (SPES) is presently under construction at the Legnaro National Laboratories of INFN. The SPES facility is based on the ISOL method using an UCx Direct Target ...able to sustain a power of 10 kW. The primary proton beam is provided by a high current Cyclotron accelerator with energy of 35-70 MeV and a beam current of 0.2-0.5 mA. Neutron-rich radioactive ions are produced by proton induced fission on an Uranium target at an expected fission rate of the order of 1013 fissions per second. After ionization and selection the exotic isotopes are re-accelerated by the ALPI superconducting LINAC at energies of 10A MeV for masses in the region A=130 amu. The expected secondary beam rates are of the order of 107 - 109 pps. Aim of the SPES facility is to deliver high intensity radioactive ion beams of neutron rich nuclei for nuclear physics research as well as to be an interdisciplinary research centre for radio-isotopes production for medicine and for neutron beams.
The authors tried to estimate the prevalence of urinary incontinence in children between 6 and 13/14 years by administering an anonymous questionnaire to students of primary and secondary 1 degree ...schools of the City of Verona. The disorder is found to be present only at night in 1.9% (male)--0.6% (females) in the elementary school; also in daytime in 2% (males)--1.3% (females) in the elementary school and 0.7% (male)--1.2% (females) in the middle school; only in daytime in 2,7% (males)--3,5% (females) in the elementary school and 2% (male)--3,3% (females) in the middle school. These data may be underestimated by the low adhesion to the survey by adolescents.
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