Talent training has a strong social constraint and economic dominance, and is closely related to regional economic development with two-way interaction. Context is any information that can be used to ...describe the situation and characteristics of an object, including time, location, social relationships, natural conditions, and project characteristics. Regional economic development is influenced by the process of multiple types of contextual elements, but traditional development models do not consider or only take into account a single contextual element, ignoring the combined influence of multiple contextual elements. To this end, the paper proposes a model for analyzing the correlation between talent training quality and regional economic development that integrates context-awareness and random forest algorithms, modeling contextual elements as feature attributes to be considered when splitting decision trees in random forests. The experimental results show that when conducting the analysis, assigning corresponding weights to various contextual elements according to the degree of importance can improve the accuracy of the recommendations. The prediction accuracy of the random forest model is higher under different data sampling ratios.
Photodynamic therapy (PDT), as a non-invasive therapeutic modality that is alternative to radiotherapy and chemotherapy, is extensively investigated for cancer treatments. Although conventional ...organic photosensitizers (PSs) are still widely used and have achieved great progresses in PDT, the disadvantages such as hydrophobicity, poor stability within PDT environment and low cell/tissue specificity largely limit their clinical applications. Consequently, nano-agents with promising physicochemical and optical properties have emerged as an attractive alternative to overcome these drawbacks of traditional PSs. Herein, the up-to-date advances in the fabrication and fascinating applications of various nanomaterials in PDT have been summarized, including various types of nanoparticles, carbon-based nanomaterials, and two-dimensional nanomaterials, etc. In addition, the current challenges for the clinical use of PDT, and the corresponding strategies to address these issues, as well as future perspectives on further improvement of PDT have also been discussed.
In this paper, a co-word method based on keywords from funded project is proposed to map the research trends. Firstly, the keywords of funded project are used to describe the rsearch topic ...statistically. Then, co-word analysis, including cluster analysis, social network analysis, is adopted to study the relationship of each research topic. The projects of Management Science and Engineering in National Natural Science Foundation of China during 2011-2015 are collected as the empirical data. The data is composed of General Project, Youth Project, and Regional Project. The results show that the focus of researches are Game Theory, Supply Chain Management, Complex Network, Data Mining, Optimize, Risk Management, and Data Envelopment Analysis. Moreover, Game Theory, Supply Chain Management, and Data Mining are hot topics. The research fields in Management Science and Engineering in China are varied, and the well developed and core research fields are fewer.
In order to improve the accuracy of the parameters needed in the discrete element method (DEM) simulation process of wet-sticky feed raw materials, the JKR contact model in DEM was used to calibrate ...and verify the physical parameters of wet-sticky feed raw materials. Firstly, the parameters that have a significant effect on the angle of repose were screened using a Plackett-Burman design, and the screened parameters were: MM rolling friction coefficient, MM static friction coefficient, and JKR surface energy. Then, the three screened parameters were selected as the influencing factors and the accumulation angle of repose was selected as evaluating indicator; thus, the performance optimization experiments were carried out with the quadratic orthogonal rotation design. Taking the experimentally measured angle of repose value of 54.25°as the target value, the significance parameters were optimized, and the optimal combination was obtained : MM rolling friction factor was 0.21, MM static friction factor was 0.51, and JKR surface energy was 0.65. Finally, the angle of repose and SPP tests were compared under the calibrated parameters. The results showed that the relative error of experimental and simulated tests in angle of repose was 0.57%, and the compression displacement and compression ratio of the experimental and simulated tests in SPP were 1.01% and 0.95%, respectively, which improved the reliability of the simulated results. The research findings provide a reference basis for simulation study and optimal design of related equipment for feed raw materials.
Zizania latifolia is a popular aquatic vegetable in China because of its enlarged edible stems resulting from persistent infection by a fungal endophyte, Ustilago esculenta. Fenaminosulf (FM) is a ...germicide that can be used to improve agricultural crop yields. In Z. latifolia fields, appropriate spraying of FM not just controls diseases, but also promotes an earlier harvest of Z. latifolia. In this study, we show that the timing of gall formation was advanced and the plant's yield was increased significantly under a high concentration treatment of FM. Yet FM had a strong inhibitory effect on the growth of U. esculenta in vitro, while the transcript levels of mating-type alleles, cell metabolism-related genes and chitin synthase genes were all substantially downregulated. Through a transcriptome analysis, we investigated changes in gene expression of the host Z. latifolia and fungal endophyte U. esculenta in response to FM. FM directly affected the growth of Z. latifolia by altering the expression level of genes involved in plant-pathogen interactions, plant hormone signal transduction and some metabolism pathways. By contrast, FM had little effect on U. esculenta growing inside of Z. latifolia. Collectively, our results provide a more in-depth understanding of the molecular processes that promote gall formation in Z. latifolia, while also identifying potential targets for genetic manipulation to improve the yield and quality of Z. latifolia, in a safer and more effective way.
In recent years, sensor-based human activity recognition has attracted lots of studies. This paper presents a single wearable triaxial accelerometer-based human activity recognition system, which can ...be used in the real life of activity monitoring. The sensor is attached around different parts of the body: waist and left ankle, respectively. In order to improve the accuracy and reduce the computational complexity, the ensemble empirical mode decomposition (EEMD)-based features and the feature selection (FS) method are introduced, respectively. Considering the feature interaction, a game theory-based FS method is proposed to evaluate the features. Relevant and distinguished features that are robust to the placement of sensors are selected. In the experiment, the data acquired from the two different parts of the body, waist and ankle, are utilized to evaluate the proposed FS method. To verify the effectiveness of the proposed method, k-nearst neighbor and support vector machine are used to recognize the human activities from waist and ankle. Experiment results demonstrate the effectiveness of the introduced EEMD-based features for human activity recognition. Compared with the representative FS methods, including Relief-F and minimum-redundancy maximum-relevance, the proposed FS approach selects fewer features and provides higher accuracy. The results also show that the triaxial accelerometer around the waist produces optimal results.
High-voltage heat release from batteries can cause safety issues for electric vehicles. Relevant scientific research work is carried out in the laboratory. The battery safety of laboratory ...experiments should not be underestimated. In order to evaluate the safety performance of batteries in the laboratory testing of driving conditions of electric vehicles, this paper simulated and compared the discharge characteristics of two common batteries (lithium iron phosphate (LFP) battery and nickel–cobalt–manganese (NCM) ternary lithium battery) in three different operating conditions. The operating conditions are the NEDC (New European Driving Cycle), WLTP (World Light Vehicle Test Procedure) and CLTC-P (China light vehicle test cycle) for normal driving of electric vehicles. LFP batteries have a higher maximum voltage and lower minimum voltage under the same initial voltage conditions, with a maximum voltage difference variation of 11 V. The maximum current of WLTP is significantly higher than NEDC and CLTC-P operating conditions (>20 A). Low current discharge conditions should be emulated in teaching simulation and experiments for safety reasons. The simulation data showed that the LFP battery had good performance in maintaining the voltage plateau and discharge voltage stability, while the NCM battery had excellent energy density and long-term endurance.
Transforming growth factor β (TGF-β) superfamily genes can regulate various processes, especially in embryogenesis, adult development, and homeostasis. To understand the evolution and divergence ...patterns of the TGF-β superfamily in scallops, genome-wide data from the Bay scallop (Argopecten irradians), the Zhikong scallop (Chlamys farreri) and the Yesso scallop (Mizuhopecten yessoensis) were systematically analysed using bioinformatics methods.
Twelve members of the TGF-β superfamily were identified for each scallop. The phylogenetic tree showed that these genes were grouped into 11 clusters, including BMPs, ADMP, NODAL, GDF, activin/inhibin and AMH. The number of exons and the conserved motif showed some differences between different clusters, while genes in the same cluster exhibited high similarity. Selective pressure analysis revealed that the TGF-β superfamily in scallops was evolutionarily conserved. The spatiotemporal expression profiles suggested that different TGF-β members have distinct functions. Several BMP-like and NODAL-like genes were highly expressed in early developmental stages, patterning the embryonic body plan. GDF8/11-like genes showed high expression in striated muscle and smooth muscle, suggesting that these genes may play a critical role in regulating muscle growth. Further analysis revealed a possible duplication of AMH, which played a key role in gonadal growth/maturation in scallops. In addition, this study found that several genes were involved in heat and hypoxia stress in scallops, providing new insights into the function of the TGF-β superfamily.
Characteristics of the TGF-β superfamily in scallops were identified, including sequence structure, phylogenetic relationships, and selection pressure. The expression profiles of these genes in different tissues, at different developmental stages and under different stresses were investigated. Generally, the current study lays a foundation for further study of their pleiotropic biological functions in scallops.
External oil supply risk is an important aspect of energy security and oil import diversification is viewed as one of the most effective measures to reduce supply risk. By using the diversification ...index approach, this research attempts to assess external oil supply risks of oil importers with consideration of two key factors associated with oil suppliers, country risk and potential oil exports capacity. The former can be used to reflect the oil supply risk associated with oil suppliers' macro-economic and socio-political stability and the latter is directly related with the physical availability of oil. The empirical research on China, Japan, the US and EU demonstrates that Japan's oil importing strategy is more concerned about potential exports of oil suppliers than country risk; the EU's oil imports have a good balance between country risk and potential exports of oil suppliers; the US has successfully diversified its oil imports to maintain the security of its external oil supply. With the rapid increase in oil demand, China has changed its oil import policy by expanding oil trade partners and switching to suppliers with high potential oil exports. Some further suggestions are presented for China to ensure its oil supply security in the future.
•The external oil supply risk is evaluated from the perspective of diversification.•Country risk and potential exports are introduced to modify diversification index.•The focus of oil imports policy among the four largest economies is quite different.•China's oil imports policy began to focus on oil potential exports from 2003.
Asexual development is the main propagation and transmission mode of Beauveria bassiana and the basis of its pathogenicity. The regulation mechanism of conidiation and the key gene resources for ...utilization are key links to improving the conidia yield and quality of Beauveria bassiana. Their clarification may promote the industrialization of fungal pesticides. Here, we compared the regulation of morphology, resistance to external stress, virulence, and nutrient utilization capacity between the upstream developmental regulatory gene fluG and the key genes brlA, abaA, and wetA in the central growth and development pathway. The results showed that the ΔbrlA and ΔabaA mutants completely lost the capacity to conidiate and that the ΔwetA mutant had seriously reduced conidiation capacity. Although the deletion of fluG did not reduce the conidiation ability as much as deletions of brlA, abaA, and wetA, it significantly reduced the fungal response to external stress, virulence, and nutrient utilization, while the deletion of the three other genes had little effect. Via transcriptome analysis and screening the yeast nuclear system library, we found that the differentially expressed genes in the ΔfluG mutants were concentrated in the signaling pathways of ABC transporters, propionate metabolism, tryptophan metabolism, DNA replication, mismatch repair, and fatty acid metabolism. FluG directly acted on 40 proteins that were involved in various signaling pathways such as metabolism, oxidative stress, and cell homeostasis. The analysis indicated that the regulatory function of fluG was mainly involved in DNA replication, cell homeostasis, fungal growth and metabolism, and the response to external stress. Our results revealed the biological function of fluG in asexual development and the responses to several environmental stresses as well as its influence on the asexual development regulatory network in B. bassiana.
PDF
