The Electron-Ion Collider (EIC), planned for construction at Brookhaven National Laboratory, will consist of two intersecting beams of intense electrons and high-energy protons or heavier atomic ...nuclei. The collider will need many demanding components, including high field superconducting magnets for the Interaction Region (IR). It has been decided that a prototype of one such magnet, the B1pF dipole, shall be built, to validate design choices common to all Rutherford cable dipole and quadrupole IR magnets. B1pF is one of several high field magnets in the interaction region whose design is based on the 15.1 mm wide NbTi cable, a cable like the one used in the main dipole coil of the Large Hadron Collider (LHC) at CERN. The current design is based on a single layer coil with an inner diameter of 300 mm and magnetic length of ∼3 m which generates a magnetic field at the center of the magnet of about 3.7 T at a current of ∼11 kA at design. This paper presents the mechanical design of the B1pF dipole magnet, and the R&D effort associated with the development of the prototype, including tests for successfully winding and curing coils of the needed configuration into proper structural and magnetic elements, and including a multilayer magnetic return yoke which meets field requirements while providing an initial reduced structure suitable for operational testing in an existing test facility.
Direct oral anticoagulants (DOACs), such as apixaban, rivaroxaban, and dabigatran, are increasingly being used to provide prophylaxis and treatment for arterial and venous thromboembolism. Multiple ...procedural subspecialties have implemented guidelines detailing time frames for perioperative DOAC interruption; however, the impact of perioperative DOAC interruption in patients undergoing dermatologic surgery is currently unknown, and evidence-based guidelines are lacking.
To assess the 30-day postoperative rate of thrombotic complications (ischemic stroke, transient ischemic attack, systemic embolism, deep vein thrombosis DVT and pulmonary embolism) in patients with nonvalvular atrial fibrillation (AF) or a history of DVT who underwent perioperative DOAC interruption during dermatologic surgery.
A retrospective medical record review was performed of all patients with AF or a history of DVT who underwent perioperative DOAC interruption during dermatologic surgery at Advanced Dermatologic Surgery and the University of Kansas Medical Center between January 1, 2016, and August 31, 2020.
Among 806 operations, comprising 750 Mohs micrographic operations (93.1%) and 56 excisions (6.9%), 1 patient (0.14% of patients with AF) sustained a transient ischemic attack and 2 patients (0.25% of all patients) sustained minor bleeding complications during the 30-day postoperative period.
Perioperative DOAC interruption appears to be safe and efficacious in dermatologic surgery.
