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  • Interleukin-17 Family Membe... Interleukin-17 Family Members and Inflammation
    Kolls, Jay K.; Lindén, Anders Immunity, 10/2004, Volume: 21, Issue: 4
    Book Review, Journal Article
    Peer reviewed
    Open access

    IL-17A was cloned more than 10 years ago and six IL-17 family members (IL-17A-F) have subsequently been described. IL-17A is largely produced by activated memory T lymphocytes but stimulates innate ...
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23.
  • Interleukin‐22 treatment am... Interleukin‐22 treatment ameliorates alcoholic liver injury in a murine model of chronic‐binge ethanol feeding: Role of signal transducer and activator of transcription 3
    Ki, Sung Hwan; Park, Oygi; Zheng, Mingquan ... Hepatology (Baltimore, Md.), October 2010, Volume: 52, Issue: 4
    Journal Article
    Peer reviewed
    Open access

    Interleukin‐22 (IL‐22), a recently identified member of the IL‐10 family of cytokines that is produced by Th17 and natural killer cells, plays an important role in controlling bacterial infection, ...
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24.
  • Th17 cell based vaccines in... Th17 cell based vaccines in mucosal immunity
    Kumar, Pawan; Chen, Kong; Kolls, Jay K Current opinion in immunology, 06/2013, Volume: 25, Issue: 3
    Journal Article
    Peer reviewed
    Open access

    Highlights • Th17 responses show protection against both bacterial and fungal pathogens. • Mucosal and systemic vaccines can elicit protective Th17 responses. • Th17 responses can mediate serotype ...
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25.
  • Host defenses against bacte... Host defenses against bacterial lower respiratory tract infection
    Eddens, Taylor; Kolls, Jay K Current opinion in immunology, 08/2012, Volume: 24, Issue: 4
    Journal Article
    Peer reviewed
    Open access

    Highlights ► Pattern recognition receptors respond to a wide variety of bacterial pathogens in the lung. ► IL-23 stimulates innate production of IL-17 and IL-22 which increase lung defenses. ► CD4+ T ...
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26.
  • Microbiological Laboratory ... Microbiological Laboratory Testing in the Diagnosis of Fungal Infections in Pulmonary and Critical Care Practice. An Official American Thoracic Society Clinical Practice Guideline
    Hage, Chadi A; Carmona, Eva M; Epelbaum, Oleg ... American journal of respiratory and critical care medicine, 09/2019, Volume: 200, Issue: 5
    Journal Article
    Peer reviewed
    Open access

    Fungal infections are of increasing incidence and importance in immunocompromised and immunocompetent patients. Timely diagnosis relies on appropriate use of laboratory testing in susceptible ...
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27.
  • The role of Th17 cytokines ... The role of Th17 cytokines in primary mucosal immunity
    Kolls, Jay K; Khader, Shabaana A Cytokine & growth factor reviews, 12/2010, Volume: 21, Issue: 6
    Journal Article
    Peer reviewed
    Open access

    Abstract The T helper type 17 (Th17) lineage of CD4+ T-cells produce several effector molecules including IL-17A, IL-17F, IL-21, and IL-22. In addition to CD4+, αβ T-cells, these cytokines can be ...
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28.
  • MCPIP1 Endoribonuclease Act... MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation
    Garg, Abhishek V.; Amatya, Nilesh; Chen, Kong ... Immunity (Cambridge, Mass.), 09/2015, Volume: 43, Issue: 3
    Journal Article
    Peer reviewed
    Open access

    Interleukin-17 (IL-17) induces pathology in autoimmunity and infections; therefore, constraint of this pathway is an essential component of its regulation. We demonstrate that the signaling ...
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  • Spelunking in Sputum: Singl... Spelunking in Sputum: Single-Cell RNA Sequencing Sheds New Insights into Cystic Fibrosis
    Iwanaga, Naoki; Kolls, Jay K American journal of respiratory and critical care medicine, 11/2020, Volume: 202, Issue: 10
    Journal Article
    Peer reviewed
    Open access

    Iwanaga and Kolls discuss the study by Schupp et al who performed a single-cell RNAseq analyses in sputum between nine cystic fibrosis (CF) subjects and five healthy control subjects. The authors ...
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30.
  • An Emerging Role of B Cell ... An Emerging Role of B Cell Immunity in Susceptibility to Pneumocystis Pneumonia
    Kolls, Jay K American journal of respiratory cell and molecular biology, 03/2017, Volume: 56, Issue: 3
    Journal Article
    Peer reviewed
    Open access

    Importantly, they chose a 14-day time point after Pneumocystis inoculation, as this time point coincided with the induction of adaptive immune responses that are just initializing clearance, yet ...
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