The H7 system was populated in the H2(He8,He3)H7 reaction with a 26 AMeV He8 beam. The H7 missing mass energy spectrum, the H3 energy and angular distributions in the H7 decay frame were ...reconstructed. The H7 missing mass spectrum shows a peak, which can be interpreted either as unresolved 5/2+ and 3/2+ doublet or one of these states at 6.5(5) MeV. The data also provide indications of the 1/2+ ground state of H7 located at 1.8(5) MeV with quite a low population cross section of ∼25 μb/sr within angular range θc.m.≃(17°-27°).
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A clinical case of the co-medication of valproic acid and cilastatin/imipenem in a 17-year-old girl with generalized tonic-clonic seizures is described. As an antiepileptic therapy, the child was ...prescribed valproic acid, the concentration of which in the blood plasma was more than 80 µg/ml, and seizures were not observed during this therapy. At the same time, due to the developed pneumonia, the girl was imipenem/cilastatin prescribed. Co-medication of drugs led to a decrease in the concentration of valproic acid in the blood plasma less than 50 µg/ ml, relapse of epileptic seizures was noted. Correction of antiepileptic therapy with phenobarbital did not lead to the seizure control. The removal of imipenem/ cilastatin contributed to the increase in the concentration of valproic acid in blood plasma above 50 µg/ ml, which corresponds to the recommended therapeutic range. Within two weeks after discontinuation of imipenem/ cilastatin, the concentration of valproic acid reached values as close as possible to the values before the start of antibiotic therapy. The authors of the article concluded that it is necessary to conduct therapeutic drug monitoring in children receiving valproic acid and imipenem/ cilastatin (antibiotic of carbapenem group), based on the known mechanisms of pharmacokinetic interaction.
The most remote isotope from the proton dripline (by 4 atomic mass units) has been observed: K31. It is unbound with respect to three-proton (3p) emission, and its decays have been detected in flight ...by measuring the trajectories of all decay products using microstrip detectors. The 3p emission processes have been studied by the means of angular correlations of S28+3p and the respective decay vertices. The energies of the previously unknown ground and excited states of K31 have been determined. This provides its 3p separation energy value S3p of −4.6(2) MeV. Upper half-life limits of 10 ps of the observed K31 states have been derived from distributions of the measured decay vertices.
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Studies were conducted to obtain a complex enzyme preparation that allows efficient hydrolysis of the main plant nonstarch polysaccharides (cellulose, xylans, and pectin). The goal of the studies was ...to optimize the composition of a fermentation medium for the submerged cultivation of the new mutant strain
T. reesei
Co-44, a highly active producer of endo-carbohydrases. A concentrate of low molecular soy components was chosen as the inducer of the key carbohydrase biosynthesis by the strain. This concentrate provided the maximum (more than eightfold) increase in polygalacturonase activity and an increased level of endoglucanase and xylanase biosynthesis. After the cultivation of
T. reesei
Co-44 under optimized conditions, a complex enzyme preparation, Xylorizin K4, was obtained, and its physicochemical properties were studied. The presence of endopolygalacturonase (GH28)
T. reesei
in Xylorizin K4 was confirmed via electrophoresis and MALDI⎯TOF mass spectrometry
.
The studies show the potential of Xylorizin K4 application for the production of soy-protein concentrates to eliminate the main soybean nonstarch polysaccharides.
The hyperspherical harmonics approach is especially suited to studies of true three-body decays. Reducing the hyperspherical equations set to a single-channel approximation provides the basis for ...using the standard quasi-classical expression for calculating resonance widths. It is shown that the quasi-classical approach is itself quite precise when applied to the three-body single-channel effective potentials. However, reduction to the single-channel formalism seems to be unacceptable, as it leads to considerable overestimation of decay widths.
The proton and deuteron pickup reactions
and
were studied with the
radioactive beam produced by the new fragment separator ACCULINNA-2 at FLNR, JINR. These measurements were initially motivated as ...the test reactions intended for the elucidation of results obtained in the study of the extremely neutron-rich
H and
H systems created in the
and
reactions with the use of the same setup. In the
reaction the
Li ground-state (
) and its first excited state (2.69 MeV,
) were identified in the low-energy region of its excitation spectrum. The differential cross sections for the
population were extracted at the forward center-of-mass angles (
) and compared with the FRESCO calculations. Spectroscopic factor of
, derived by a model suggesting the
clustering was found in accord with the experimental data. The energy spectrum of
Li populated in the
reaction shows the strong peak which corresponds to the excitation of the second excited state of
Li (2.25 MeV,
). The fact that the ground and the first excited states of
Li were not observed in this reaction is consistent with the shell-model structure of the nuclei involved.
A new two-coordinate position-sensitive spectrometer for the measurements of spatial and energy distribution of ionizing particles was developed. The sensitive elements of the device are two ...orthogonal 64 strip semiconductor detectors whose signals are read out by two Application-Specific Integrated Circuits (ASIC) IDE1140 comprising 64 spectrometric channels each. Control, pre-processing data acquisition and transfer to a computer are carried out using FPGA circuit EP3C16Q240. The main spectrometer characteristics obtained in the measurements are: equivalent noise charge of 0.7 fC and integral nonlinearity is below 1% in the range from 5 to 160 fC.
The extremely neutron-rich systems 7H, 6H were studied in the 2H(8He, 3He)7H and 2H(8He, 4He)6H proton and deuteron pickup reactions with a 26 AMeV secondary 8He beam produced at the new ACCULINNA-2 ...fragment separator. In addition, the same proton and deuteron pickup reactions were generated using the 42 AMeV 10Be beam, and the population of low-lying 9Li and 8Li states was measured in reactions 2H(10Be,3He)9Li and 2H(10Be,4He)8Li, respectively. The latter were used as reference measurements in order to check the setup calibration over the excitation energy of 7,6H and to determine the real experimental energy resolution which was compared with Monte Carlo calculations. The corresponding results obtained for the superheavy hydrogen systems 7H, 6H are presented and discussed. Typical excitation spectra of the 9Li and 8Li nuclei are also shown.
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