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  • A phase 1, open-label study... A phase 1, open-label study of LCAR-B38M, a chimeric antigen receptor T cell therapy directed against B cell maturation antigen, in patients with relapsed or refractory multiple myeloma
    Zhao, Wan-Hong; Liu, Jie; Wang, Bai-Yan ... Journal of hematology and oncology, 12/2018, Volume: 11, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Chimeric antigen receptor (CAR) T cell therapy has demonstrated proven efficacy in some hematologic cancers. We evaluated the safety and efficacy of LCAR-B38M, a dual epitope-binding CAR T cell ...
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  • Chemokines and their recept... Chemokines and their receptors promoting the recruitment of myeloid-derived suppressor cells into the tumor
    Li, Bao-Hua; Garstka, Malgorzata A.; Li, Zong-Fang Molecular immunology, January 2020, 2020-01-00, 20200101, Volume: 117
    Journal Article
    Peer reviewed

    •We describe the chemokines and their receptors, including CCL2/CCL12-CCR2, CCL3/4/5-CCR5, CCL15-CCR1, CX3CL1/CCL26-CX3CR1, CXCL5/2/1-CXCR2, CXCL8-CXCR1/2, CCL21-CCR7, CXCL13-CXCR5 axes important for ...
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  • Spleen contributes to restr... Spleen contributes to restraint stress induced changes in blood leukocytes distribution
    Jiang, Wei; Li, Yu; Sun, Jin ... Scientific reports, 07/2017, Volume: 7, Issue: 1
    Journal Article
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    Open access

    Psychological stress has great impacts on the immune system, particularly the leukocytes distribution. Although the impacts of acute stress on blood leukocytes distribution are well studied, however, ...
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  • Circadian time‐ and sleep‐d... Circadian time‐ and sleep‐dependent modulation of cortical parvalbumin‐positive inhibitory neurons
    Zong, Fang‐Jiao; Min, Xia; Zhang, Yan ... The EMBO journal, 01 February 2023, Volume: 42, Issue: 3
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    Open access

    Parvalbumin‐positive neurons (PVs) are the main class of inhibitory neurons in the mammalian central nervous system. By examining diurnal changes in synaptic and neuronal activity of PVs in the ...
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  • Transmission patterns of CO... Transmission patterns of COVID-19 in the mainland of China and the efficacy of different control strategies: a data- and model-driven study
    Zu, Jian; Li, Miao-Lei; Li, Zong-Fang ... Infectious diseases of poverty, 07/2020, Volume: 9, Issue: 1
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    The coronavirus disease 2019 (COVID-19) outbreak has seriously endangered the health and lives of Chinese people. In this study, we predicted the COVID-19 epidemic trend and estimated the efficacy of ...
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  • Perspectives of traditional... Perspectives of traditional Chinese medicine in pancreas protection for acute pancreatitis
    Li, Jun; Zhang, Shu; Zhou, Rui ... World journal of gastroenterology : WJG, 05/2017, Volume: 23, Issue: 20
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    Acute pancreatitis(AP)is one of the most common diseases.AP is associated with significant morbidity and mortality,but it lacks specific and effective therapies.Traditional Chinese medicine(TCM)is ...
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  • Protective Role of Collecti... Protective Role of Collectin 11 in a Mouse Model of Rheumatoid Arthritis
    Wang, Na; Wu, Weiju; Qiang, Cui ... Arthritis & rheumatology (Hoboken, N.J.), August 2021, 2021-08-00, 20210801, Volume: 73, Issue: 8
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    Objective Collectin 11 (CL‐11) is a soluble C‐type lectin, a mediator of innate immunity. Its role in autoimmune disorders is unknown. We undertook this study to determine the role of CL‐11 in a ...
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  • The spleen contributes to t... The spleen contributes to the increase in PMN-MDSCs in orthotopic H22 hepatoma mice
    Li, Bao-Hua; Jiang, Wei; Zhang, Shu ... Molecular immunology, September 2020, 2020-09-00, 20200901, Volume: 125
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    •PMN-MDSCs were increased and dominant in H22 orthotopic hepatoma mice.•The spleen contributed to the increase of PMN-MDSCs in H22 orthotopic hepatoma mice.•Splenic PMN-MDSCs could be mobilized to ...
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  • Calcium signaling of pancre... Calcium signaling of pancreatic acinar cells in the pathogenesis of pancreatitis
    Li, Jun; Zhou, Rui; Zhang, Jian ... World journal of gastroenterology : WJG, 11/2014, Volume: 20, Issue: 43
    Journal Article
    Open access

    Pancreatitis is an increasingly common and sometimes severe disease that lacks a specific therapy.The pathogenesis of pancreatitis is still not well understood.Calcium(Ca2+)is a versatile carrier of ...
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  • The C3a/C3aR axis mediates ... The C3a/C3aR axis mediates anti-inflammatory activity and protects against uropathogenic E coli–induced kidney injury in mice
    Wu, Kun-Yi; Zhang, Ting; Zhao, Guo-Xiu ... Kidney international, September 2019, 2019-09-00, 20190901, Volume: 96, Issue: 3
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    Both the C3a/C3aR and C5a/C5aR1 axes are regarded as important pathways for inducing and regulating inflammatory responses. It is well documented that the C5a/C5aR1 axis is a potent inflammatory ...
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