A popular commercially available oligonucleotide microarray technology employs sets of 25 base pair oligonucleotide probes for measurement of gene expression levels. A mathematical algorithm is ...required to compute an estimate of gene expression from the multiple probes. Previously proposed methods for summarizing gene expression data have either been substantially ad hoc or have relied on model assumptions that may be easily violated. Here we present a new algorithm for calculating gene expression from probe sets. Our approach is functionally related to leave-one-out cross-validation, a non-parametric statistical technique that is often applied in limited data situations. We illustrate this approach using data from our study seeking a molecular fingerprint of STAT3 regulated genes for early detection of human cancer.
Guizotia abyssinica (L.F.) Cass. is one of the important oilseed crops cultivated in India. The seed of the plant is used by the tribal and rural people of our country as a source of edible oil. The ...present investigation of the Niger plant deals with the study of the back cross-program and improvement in the variety. Unknown local variety (A) of niger was selected as a non-recurrent parent because of having some desirable characters like less vegetative growth (dwarf), resistance to waterlogged condition, and large seed grains while IGP-76 variety (B) was selected as a recurrent parent and used as a female having characters like small black grains, resistant to leaf-eating cater Piller and powdery mildew result shows successfully transfer of the characters in the F1 generation. The average number of capitulum/plant shows very good and positive results in F1 as well as BC1 generation. As compared to the recurrent parent (B) an average number of capitulum per plant was increased in F1 generation by 14.28% and in BC1 generation by 28.5%. The table indicates that there is incensement in the average number of seeds per capitulum. The average number of seeds per capitulum was increased by 8.3% in the F1 generation and by 11.11 % in the BC1 generation as compared to the recurrent parent. Average weights of 1000 seeds were also increased in F1 generation by 31.78% and in BC1 generation by 47.28% along with the total yield per plant.
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