The aim of the present study was to explore the traditional plant knowledge of a zone of the Ligurian coast, known as Riviera spezzina (RS), Eastern Liguria, Italy.
Ethnobotanical information was ...obtained through open informal interviews. The informants were residents, belonging to families living in the study area since generations, and involved, at least partially, in agriculture.
A total of 120 botanical taxa were recorded. Ethnobotanical data included medicinal (40.4%), alimentary (46.5%), veterinary (4.6%), domestic and cosmetic (4.3%), magic and ritual (1.8%) and other uses (2.4%). Medicinal plants are used to treat a wide range of diseases, mainly disorders of digestive system, skin, and genital–urinary and respiratory traits. The key role played by undomesticated edible herbs, locally known as “erbette”, in traditional cooking recipes of RS was shown. These botanicals are rich in bioactive compounds, such as polyphenols, vitamins, complex sugars, essential fatty acids and fibers, and therefore might offer a valid protection against pathological conditions. Plant uses by RS people were compared with previous ethnobotanical literature, concerning the neighbouring areas of Liguria. Our results highlight the role of the traditional use of plants in the maintenance of health and the prevention of chronic and age-related diseases.
The current generation of ground-based imaging atmospheric Cherenkov telescopes (IACTs) operate in the very-high-energy (VHE) domain from ~100 GeV to ~100 TeV. They use electronic digital trigger ...systems to discern the Cherenkov light flashes emitted by extensive air showers (EASs), from the overwhelming light of the night sky (LoNS) background. Near the telescope energy threshold, the number of emitted Cherenkov photons by gamma-ray-induced EASs is comparable to the fluctuations of the LoNS and the photon distribution at the Cherenkov-imaging camera plane becomes patchy. This results in a severe loss of effectiveness of the digital triggers based on combinatorial logic of thresholded signals. A stereoscopic analog trigger system has been developed for improving the detection capabilities of the Major Atmospheric Gamma-ray Imaging Cherenkov (MAGIC) telescopes at the lowest energies. It is based on the analog sum of the photosensor electrical signals. In this article, the architectural design, technical performances, and configuration of this stereoscopic analog trigger, dubbed " Sum-Trigger-II ," are described.
Abstract
Imaging Atmospheric Cherenkov Telescopes (IACTs) currently in operation feature large mirrors and order of 1 ns time response to signals of a few photo-electrons produced by optical photons. ...This means that they are ideally suited for optical interferometry observations. Thanks to their sensitivity to visible wavelengths and long baselines optical intensity interferometry with IACTs allows reaching angular resolutions of tens to microarcsec. We have installed a simple optical setup on top of the cameras of the two 17 m diameter MAGIC IACTs and observed coherent fluctuations in the photon intensity measured at the two telescopes for three different stars. The sensitivity is roughly 10 times better than that achieved in the 1970’s with the Narrabri interferometer.
The influence of crop density on the remobilization of dry matter and nitrogen from vegetative plant parts to the developing grain, was investigated in the durum wheat (
Triticum durum Desf.) ...varieties Creso, Simeto and Svevo cultivated in the field at three seeding rates, 200, 250 and 400
seeds
m
−2. Variety
×
seeding rate interaction was unsignificant for all recorded characters. Grain yield declined in the order Svevo
>
Simeto
>
Creso. Yield differences mainly depended on the different number of kernels per unit land and, secondly, on mean kernel weight. Spike components differed among varieties: Svevo and Simeto showed more kernels per spikelet and Creso more spikelets per spike. Grain yield was highest with 400
seeds
m
−2 primarily due to the higher number of spikes per unit area, and secondly, to the higher mean kernel weight. Post-heading dry matter accumulation was highest in Svevo and lowest in Creso, but varieties showed a reverse order for dry matter remobilization and contribution of dry matter remobilization to grain yield. The increase of seeding rate increased both the post-heading dry matter accumulation and the dry matter remobilization from vegetative plant parts to grain. Nitrogen uptake of the whole crop and N content of grain was higher in Simeto and Svevo than in Creso. The N concentration of grain did not vary among varieties, but Svevo showed a markedly lower N concentration and N content of culms at maturity, which may be consequence of the high N remobilization efficiency performed by this variety. The N uptake by the crop was highest with 400
seeds
m
−2, but the N concentration of culms, leaves and even grain was slightly lower than with the lower seed rates. The post-heading N accumulation was by far higher in Simeto and Svevo than in Creso, whereas remobilization was highest in Svevo and lowest in Simeto. The percentage contribution of N remobilization to grain N was by far higher in Creso than in the other two varieties. Post-heading N accumulation and N remobilization were highest with the highest plant density, but the contribution of N remobilization to N grain content did not differ between seeding rates.
Purpose
Nonalcoholic fatty liver disease (NAFLD) is defined by excessive lipid accumulation in the liver and involves an ample spectrum of liver diseases, ranging from simple uncomplicated steatosis ...to cirrhosis and hepatocellular carcinoma. Accumulating evidence demonstrates that high fructose intake enhances NAFLD development and progression promoting inhibition of mitochondrial β-oxidation of long-chain fatty acids and oxidative damages.
l
-Carnitine (LC), involved in β-oxidation, has been used to reduce obesity caused by high-fat diet, which is beneficial to ameliorating fatty liver diseases. Moreover, in the recent years, various studies have established LC anti-oxidative proprieties. The objective of this study was to elucidate primarily the underlying anti-oxidative mechanisms of LC in an in vitro model of fructose-induced liver steatosis.
Methods
Human hepatoma HepG2 cells were maintained in medium supplemented with LC (5 mM LC) with or without 5 mM fructose (F) for 48 h and 72 h. In control cells, LC or F was not added to medium. Fat deposition, anti-oxidative, and mitochondrial homeostasis were investigated.
Results
LC supplementation decreased the intracellular lipid deposition enhancing AMPK activation. However, compound C (AMPK inhibitor-10 μM), significantly abolished LC benefits in F condition. Moreover, LC, increasing PGC1 α expression, ameliorates mitochondrial damage-F induced. Above all, LC reduced ROS production and simultaneously increased protein content of antioxidant factors, SOD2 and Nrf2.
Conclusion
Our data seemed to show that LC attenuate fructose-mediated lipid accumulation through AMPK activation. Moreover, LC counteracts mitochondrial damages and reactive oxygen species production restoring antioxidant cellular machine. These findings provide new insights into LC role as an AMPK activator and anti-oxidative molecule in NAFLD.
Reynoutria × bohemica is an invasive species causing significant damage to native ecosystems in North America and Europe.
In this work, we performed an in‐depth micromorphological characterisation of ...the extrafloral nectaries (EFN), during their secretory and post‐secretory phases, in combination with field monitoring of nectary activity over time and the qualitative pool of insect visitors.
EFN consist of secretory trichomes and vascularised parenchyma. Polysaccharides, lipids and proteins were histochemically detected in all trichome cells; phenolic substances were detected in parenchyma cells. Our data indicate that all nectary regions are involved in nectar production and release, constituting a functional unit. Moreover, the main compound classes of nectar and their transfer change over time: first, granulocrine secretion for sugars prevails, then eccrine secretion of the lipophilic fraction takes place. Active nectaries are mainly located in the apical portion of the stem during the growth phase (April–May), when we detected the highest number of individuals visited by ants; from mid‐August onwards, during flowering, the number of active nectaries declined then ceased production (September), with a concomitant decrease in visits by the ants. The spectrum of nectar‐foraging ants mainly included representatives of the genera Formica, Lasius and Camponotus.
Reynoutria × bohemica produces an attractive secretion able to recruit local ants that may potentially act as ‘bodyguards’ for protecting young shoots, reducing secretions during the blooming stage. This defence mechanism against herbivores is the same as that displayed by the parental species in its native areas.
We discuss a method to constrain the distance of blazars with unknown redshift using combined observations in the GeV and TeV regimes. We assume that the Very High Energies (VHE) spectrum corrected ...for the absorption through the interaction with the extragalactic background light cannot be harder than the spectrum in the Fermi/Large Area Telescope (LAT) band. Starting from the observed VHE spectral data we derive the EBL-corrected spectra as a function of the redshift z and fit them with power laws to be compared with power-law fits to the LAT data. We apply the method to all TeV blazars detected by LAT with known distance and derive an empirical law describing the relation between the upper limits and the true redshifts that can be used to estimate the distance of unknown redshift blazars. Using different EBL models leads to systematic changes in the derived upper limits. Finally, we use this relation to infer the distance of the unknown redshift blazar PKS 1424+240.
The basal forebrain (BF) plays an important role in modulating cortical activity and influencing attention, learning and memory. These activities are fulfilled importantly yet not entirely by ...cholinergic neurons. Noncholinergic neurons also contribute and comprise GABAergic neurons and other possibly glutamatergic neurons. The aim of the present study was to estimate the total number of cells in the BF of the rat and the proportions of that total represented by cholinergic, GABAergic and glutamatergic neurons. For this purpose, cells were counted using unbiased stereological methods within the medial septum, diagonal band, magnocellular preoptic nucleus, substantia innominata and globus pallidus in sections stained for Nissl substance and/or the neurotransmitter enzymes, choline acetyltransferase (ChAT), glutamic acid decarboxylase (GAD) or phosphate-activated glutaminase (PAG). In Nissl-stained sections, the total number of neurons in the BF was estimated as ∼355,000 and the numbers of ChAT-immuno-positive (+) as ∼22,000, GAD+ ∼119,000 and PAG+ ∼316,000, corresponding to ∼5%, ∼35% and ∼90% of the total. Thus, of the large population of BF neurons, only a small proportion has the capacity to synthesize acetylcholine (ACh), one third to synthesize GABA and the vast majority to synthesize glutamate (Glu). Moreover, through the presence of PAG, a proportion of ACh- and GABA-synthesizing neurons also has the capacity to synthesize Glu. In sections dual fluorescent immunostained for vesicular transporters, vesicular glutamate transporter (VGluT) 3 and not VGluT2 was present in the cell bodies of most PAG+ and ChAT+ and half the GAD+ cells. Given previous results showing that VGluT2 and not VGluT3 was present in BF axon terminals and not colocalized with VAChT or VGAT, we conclude that the BF cell population influences cortical and subcortical regions through neurons which release ACh, GABA or Glu from their terminals but which in part can also synthesize and release Glu from their soma or dendrites.
An abundance of plant remains (pollen, seeds/fruits and wood) and wood artefacts was found during the excavation of an Etruscan-Roman well located at Cetamura del Chianti in Tuscany, Italy, which ...contained rich cultural and ecofact assemblages in a stratified context. The findings provide evidence for the presence of a mixed oak forest during the time span of the usage of the well. The main decline of deciduous
Quercus
, possibly due to forest clearance, is recorded during the late Etruscan period (ca. 300–100/50 B.C.). A diffusion of
Quercus ilex
occurred during the Roman period (from ca. 50 B.C. to 68 A.D.). Food plants are well represented in the well, particularly cereals and grapevine. The morphometric analysis of the grape pips suggests that fully domesticated forms were cultivated, and that wild fruits may have been gathered in the woods or harvested from weakly domesticated individuals. Some botanical finds could possibly be linked to ritual practices, although the state of preservation of the seed/fruit record, the majority waterlogged, does not meet criteria for carbonized remains used for attributing the plant remains to ritual offerings.
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