An unusual pressure sore of the nasal bridge Sleilati, Fadi H; Stephan, Henri A; Nasr, Marwan W ...
British journal of oral & maxillofacial surgery,
07/2008, Volume:
46, Issue:
5
Journal Article
Peer reviewed
Abstract We report an unusual pressure sore of the nasal bridge caused by a non-invasive ventilation mask. Conservative treatment was unsuccessful, and the defect had to be repaired, with a good ...postoperative result.
One of the major challenges in training deep neural networks for text-to-image generation is the significant linguistic discrepancy between ground-truth captions of each image in most popular ...datasets. The large difference in the choice of words in such captions results in synthesizing images that are semantically dissimilar to each other and to their ground-truth counterparts. Moreover, existing models either fail to generate the fine-grained details of the image or require a huge number of parameters that renders them inefficient for text-to-image synthesis. To fill this gap in the literature, we propose using the contrastive learning approach with a novel combination of two loss functions: fake-to-fake loss to increase the semantic consistency between generated images of the same caption, and fake-to-real loss to reduce the gap between the distributions of real images and fake ones. We test this approach on two baseline models: SSAGAN and AttnGAN (with style blocks to enhance the fine-grained details of the images.) Results show that our approach improves the qualitative results on AttnGAN with style blocks on the CUB dataset. Additionally, on the challenging COCO dataset, our approach achieves competitive results against the state-of-the-art Lafite model, outperforms the FID score of SSAGAN model by 44.
Abstract Background Aspirin has been proven to be effective in preventing preeclampsia (PE) in singleton pregnancies. However, the use of aspirin for women with twin pregnancies is still debatable. ...The purpose of our meta‐analysis is to evaluate the effectiveness of aspirin for preventing preeclampsia in twin pregnancies. Methods We searched the following databases: PubMed, Scopus, Cochrane Library and Web of Science. Twelve studies were included in the meta‐analysis. The quality assessment and ROB were executed using NOS and ROB 2 respectively. RevMan software 5.4 was used for performing the analysis. Results The pooled analysis showed no significant difference between the administration of aspirin and the control group in decreased incidence of PE, hypertensive disorders, IUGR or twin‐to‐twin discordance (RR = 0.73, CI = 0.43–1.24, p = 0.24), (RR = 0.60, CI = 0.34–1.07, p = 0.08), (RR = 0.90, CI = 0.45–1.82, p = 0.77) and (RR = 1.76, CI = 0.83–3.73, p = 0.14), respectively. However, the pooled analysis showed a statistically significant association between aspirin and decreased incidence of preterm birth (PTB) (RR = 0.58, CI = 0.39–0.86, p = 0.006). Subgroup analysis of the dose revealed a significant association between 100 mg of aspirin and decreased PE incidence compared with the control group (RR = 0.44, CI = 0.23–0.84, p = 0.01). Conclusion The overall analysis showed no significant role of Aspirin in reducing the incidence of PE. The dose subgroup analysis revealed that only 100 mg of Aspirin is effective in decreasing PE. Future multicentre randomized control trials are warranted to give us conclusive results.
Interface friction of surfaces is a major key in the performance of various types of foundations and structures subjected to earthquake ground motions. To provide adequate friction and stability, ...especially in sloped surfaces, a new snakeskin-bioinspired interface that can be utilized in geosynthetic interfaces is proposed. The primary application of these novel interfaces includes developing surfaces that provide higher interface friction in the direction of loading with anisotropy that depends on the direction of loading. The study illustrates experimental results of sliding interfaces of 3D-Printed snakeskin-bioinspired surfaces and Newmark's block under the application of the El Centro 1940 earthquake. A wooden rigid block was placed on the wedge and attached to an accelerometer. 3D-printed snakeskin-bioinspired surfaces were used as the sliding surface. The performance of the bioinspired surfaces has been assessed under the application of the earthquake ground motion. In this study, the utilization of 3D-Printed snakeskin surfaces has been shown to offer high potential for superior and reliable geosynthetic interfaces.
The total ethanolic extract (TEE) of Carduncellus eriocephalus Boiss. var. albiflora Gauba showed antioxidant, antihyperglycaemic, and antihyperlipidaemic activities, which were attributed to the ...n-butanol fraction (BF). Chemical investigation of the BF led to the isolation of a new flavonoid, kaempferol-3-O-β-D-galactopyranoside-6″-sulfate (16), and a phenyl propenyl glycoside, 1-β-D-glucopyranoside-3-phenyl-2-propenol (rosin) (6), which is reported for the first time in the family Asteraceae. Chrysoeriol (1), 3′-O-methylorobol (2), luteolin (3), quercetin (4), myricetin (5), kaempferol 3-O-α-L-arabinopyranoside (7), kaempferol 3-O-β-D-glucopyranoside (8), quercetin 3-O-β-D-glucopyranoside (12), luteolin 7-O-β-D-rutinoside (13), quercetin 3-O-β-D-rutinoside (14), apigenin 7-O-β-D-rutinoside (15), and 3,5-dicaffeoylquinic acid (17) were isolated for the first time from the genus Carduncellus, in addition to apigenin 7-O-β-D-glucopyranoside (9), chryseriol 7-O-β-D-glucopyranoside (10) and luteolin 7-O-β-D-glucopyranoside (11), which have been previously reported for C. eriocephalus.
The total ethanolic extract (TEE) of Carduncellus mareoticus (Del.) Hanelt showed antioxidant and antihyperlipidemic activities, which were attributed to the ethyl acetate fraction (EAF). Also TEE ...showed potent cytotoxic activity against a cervix cancer cell line (IC50 = 5 μg/mL) and moderate activity against a breast cancer cell line. Chemical investigation of EAF led to the isolation of a new flavonoid, 8-hydroxy-5-methoxyluteolin 7-O-β-D-glucopyranoside (11), along with ten known metabolites (1–10). Three of these compounds, isorhamnetin 3-O-β-D-glucopyranoside (7), luteolin 3′-O-β-D-glucopyranoside (8), and eriodictyol 7-O-β-D-glucopyranoside (9) are reported for the first time from the genus Carduncellus, and two compounds, chrysoeriol 7-O-β-D-glucopyranoside (6), and luteolin 7-O-β-D-glucopyranoside (10), for the first time from C. mareoticus. The rest of the isolated compounds, chrysoeriol (1), luteolin (2), quercetin (3), kaempferol 3-O-α-L-arabinopyranoside (4), and kaempferol 3-O-β-D-glucopyranoside (5) have been previously reported from the genus.
Contexte : L'apprentissage par problèmes (APP) est une méthode pédagogique largement utilisée au cours des études médicales prédoctorales. Dans notre faculté de médecine, l'initiation des étudiants à ...l'APP par des présentations magistrales a été appliquée pendant 3 années consécutives. Les animateurs de ces journées et les étudiants ont exprimé une insatisfaction et le désir d'une méthode d'initiation plus efficace. But : Nous décrivons une nouvelle méthode, basée sur l'APP, pour initier les étudiants à l'APP et aux concepts pédagogiques qui le sous-tendent et nous l'évaluons auprès des étudiants et des animateurs. Méthode : 64 étudiants ont participé à cette nouvelle méthode d'initiation. Un scénario d'un « problème d'apprentissage » qui ramène les étudiants à des concepts pédagogiques prédéfinis a été rédigé. La journée s'est déroulée en 3 phases durant lesquelles les étudiants en groupes de huit ont analysé le problème d'apprentissage en suivant toutes les étapes d'un APP : une séance aller de 90 minutes pour dégager les indices, émettre des hypothèses explicatives et définir les objectifs d'apprentissage, une phase de travail individuel de 2 heures et une séance retour de 90 minutes pour valider en groupe les nouvelles connaissances acquises et évaluer le déroulement de l'apprentissage. A la fin de l'activité, un questionnaire d'évaluation a été distribué aux étudiant et aux tuteurs. Résultats : Les fiches d'évaluation ont révélé que la majorité (83 %) des étudiants et tous les tuteurs (100 %) ont estimé que la nouvelle méthode utilisée est une bonne initiation à l'APP et aux concepts pédagogiques qui le sous-tendent. Conclusion : La méthode d'APP peut être utilisée pour initier les étudiants aux bases pédagogiques, aux stratégies d'apprentissage et à l'application de l'APP au cours de leurs études médicales.
Problem-based learning (PBL) is widely used in predoctoral medical curricula. At our faculty of medicine, students have been initiated to PBL and its underlying concepts by a series of lectures. For 3 consecutive years, students and lecturers have manifested their dissatisfaction and their need for a more efficient initiation method. Goal: We now describe a new PBL-based initiation method and test it with a group of students and tutors. Method: A total of 64 students participated in the study. A PBL scenario was designed that brings students back to predefined learning concepts. The initiation method consisted of 3 phases: A first phase of 90 minutes, during which students, in groups of 8, analyze a designated learning problem and formulates their learning objectives with their tutors. The second phase is an "individual work" session of 2 hours duration. Each student, assisted by a reference document, develops his learning objectives and constructs a scheme. The final phase consists of a session of 90 minutes. Again, in groups of 8, students and tutor discuss the learning objectives and the PBL method. At the end of the workshop, students and tutors were required to fill evaluation questionnaires. Results: Our results show that 83% of students and 100% of tutors believed that this initiation method was adequate. Conclusion: PBL is a method that can be used in order to initiate students to the basis of learning, learning strategies and the use of PBL during their medical studies.
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