SEX-LINKED HYDROCEPHALUS Needleman, Herbert L.; Root, Allen W.
Pediatrics (Evanston),
03/1963, Volume:
31, Issue:
3
Journal Article
Peer reviewed
Two families, each containing more than one hydrocephalic male member, have been reported. Chromosomal analysis has been normal in one member of each family. Reports of 11 families have been found in ...the literature with multiple male hydrocephalic members and without affected female members. From an analysis of these families it seems likely that there is a sex-linked factor in the heredity of one form of hydrocephalus.
Lipases and prostaglandin biosynthesis Isakson, P C; Raz, A; Hsueh, W ...
Advances in prostaglandin and thromboxane research,
1978, Volume:
3
Journal Article
The idiopathic hypereosinophilic syndrome (HES) comprises a diverse group of diseases that may ultimately lead to multiorgan dysfunction and death. We present a case of a man who was followed for ...over 9 years with HES that underwent malignant transformation to acute leukemia with eosinophilic features. The patient's clinical acceleration was accompanied by the development of a malignant clone that was identified with banding techniques as 46,XY,t(5:11)(p15;q13). Electron microscopy reaffirmed findings reported in earlier cases of eosinophilic leukemia. At no time during his illness were cytotoxic drugs administered. In addition to delineating the natural evolution and cytostructural details of the case, we emphasize the role of cytogenetics in the predicting of malignant variants of the hypereosinophilic syndrome and in identifying eosinophilic leukemia.
