Radiative corrections and Lorentz violation Ferrari, A. F.; Nascimento, J. R.; Petrov, A. Yu
The European physical journal. C, Particles and fields,
05/2020, Volume:
80, Issue:
5
Journal Article
Peer reviewed
Open access
Radiative corrections in Lorentz violating (LV) models have already received a lot of attention in the literature in recent years, with many instances where a LV operator in one sector of the ...Standard Model Extension (SME) generates, via loop corrections, one of the LV coefficients in the photon sector, which is probably the most understood and well constrained part of the SME. In many of these works, however, the now standard notation of the SME is not used, which can obscure the comparison of different results, and their possible phenomenological relevance. In this work, we fill this gap, trying to build up a more general perspective on the topic, bringing many of the results to the SME conventional notation and commenting on their possible phenomenological relevance. We uncover one example where a result already presented in the literature can be used to place a stronger bound on the temporal component of the
b
μ
coefficient of the fermion sector of the SME.
Metric-affine bumblebee gravity: classical aspects Delhom, Adrià; Nascimento, J. R.; Olmo, Gonzalo J. ...
The European physical journal. C, Particles and fields,
04/2021, Volume:
81, Issue:
4
Journal Article
Peer reviewed
Open access
We consider the metric-affine formulation of bumblebee gravity, derive the field equations, and show that the connection can be written as Levi-Civita of a disformally related metric in which the ...bumblebee field determines the disformal part. As a consequence, the bumblebee field gets coupled to all the other matter fields present in the theory, potentially leading to nontrivial phenomenological effects. To explore this issue we compute the post-Minkowskian, weak-field limit and study the resulting effective theory. In this scenario, we couple scalar and spinorial matter to the effective metric, and then we explore the physical properties of the VEV of the bumblebee field, focusing mainly on the dispersion relations and the stability of the resulting effective theory.
We consider the Lorentz-violating extended QED involving all nonminimal dimension-5 additive CPT-odd terms. For this theory, we investigate the generation of the Carroll–Field–Jackiw (CFJ) term and ...its higher-derivative counterparts of the first order in any of these nonminimal couplings. The CFJ term is demonstrated to vanish in the dimensional regularization scheme. We also study the question of higher-derivative divergent contributions and demonstrate that they can be eliminated by considering a given proportionality between the coefficients.
It is well known that non-local theories of gravity have been a flourish arena of studies for many reasons, for instance, the UV incompleteness of General Relativity (GR). In this paper we check the ...consistency of ST-homogeneous Gödel-type metrics within the non-local gravity framework. The non-local models considered here are ghost-free but not necessarily renormalizable since we focus on the classical solutions of the field equations. Furthermore, the non-locality is displayed in the action through transcendental entire functions of the d’Alembert operator
□
that are mathematically represented by a power series of the
□
operator. We find two exact solutions for the field equations correspondent to the degenerate (
ω
=
0
) and hyperbolic (
m
2
=
4
ω
2
) classes of ST-homogeneous Gödel-type metrics.
NAD metabolism regulates diverse biological processes, including ageing, circadian rhythm and axon survival. Axons depend on the activity of the central enzyme in NAD biosynthesis, nicotinamide ...mononucleotide adenylyltransferase 2 (NMNAT2), for their maintenance and degenerate rapidly when this activity is lost. However, whether axon survival is regulated by the supply of NAD or by another action of this enzyme remains unclear. Here we show that the nucleotide precursor of NAD, nicotinamide mononucleotide (NMN), accumulates after nerve injury and promotes axon degeneration. Inhibitors of NMN-synthesising enzyme NAMPT confer robust morphological and functional protection of injured axons and synapses despite lowering NAD. Exogenous NMN abolishes this protection, suggesting that NMN accumulation within axons after NMNAT2 degradation could promote degeneration. Ectopic expression of NMN deamidase, a bacterial NMN-scavenging enzyme, prolongs survival of injured axons, providing genetic evidence to support such a mechanism. NMN rises prior to degeneration and both the NAMPT inhibitor FK866 and the axon protective protein Wld(S) prevent this rise. These data indicate that the mechanism by which NMNAT and the related Wld(S) protein promote axon survival is by limiting NMN accumulation. They indicate a novel physiological function for NMN in mammals and reveal an unexpected link between new strategies for cancer chemotherapy and the treatment of axonopathies.
The goal of nonrestorative or non- and microinvasive caries treatment (fluoride- and nonfluoride-based interventions) is to manage the caries disease process at a lesion level and minimize the loss ...of sound tooth structure. The purpose of this systematic review and network meta-analysis was to summarize the available evidence on nonrestorative treatments for the outcomes of 1) arrest or reversal of noncavitated and cavitated carious lesions on primary and permanent teeth and 2) adverse events. We included parallel and split-mouth randomized controlled trials where patients were followed for any length of time. Studies were identified with MEDLINE and Embase via Ovid, Cochrane CENTRAL, and Cochrane Database of Systematic Reviews. Pairs of reviewers independently conducted the selection of studies, data extraction, risk-of-bias assessments, and assessment of the certainty in the evidence with the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. Data were synthesized with a random effects model and a frequentist approach. Forty-four trials (48 reports) were eligible, which included 7,378 participants and assessed the effect of 22 interventions in arresting or reversing noncavitated or cavitated carious lesions. Four network meta-analyses suggested that sealants + 5% sodium fluoride (NaF) varnish, resin infiltration + 5% NaF varnish, and 5,000-ppm F (1.1% NaF) toothpaste or gel were the most effective for arresting or reversing noncavitated occlusal, approximal, and noncavitated and cavitated root carious lesions on primary and/or permanent teeth, respectively (low- to moderate-certainty evidence). Study-level data indicated that 5% NaF varnish was the most effective for arresting or reversing noncavitated facial/lingual carious lesions (low certainty) and that 38% silver diamine fluoride solution applied biannually was the most effective for arresting advanced cavitated carious lesions on any coronal surface (moderate to high certainty). Preventing the onset of caries is the ultimate goal of a caries management plan. However, if the disease is present, there is a variety of effective interventions to treat carious lesions nonrestoratively.
An increasing number of elderly people in renal support is expected in the coming years. The objective of this study was to report the clinical and socio-demographic data of end-stage renal disease ...(ESRD) adult patients undergoing regular dialysis treatment comparing elderly (≥65 years old) and non-elderly subjects using data from the Brazilian Dialysis Registry database. The regional distribution of the sample was Southeast (48.8%), South (33.7), Northeast (13.1%), Midwest (5.1%), and North (0.1%). A total of 18,030 patients were included in the analysis with elderly patients accounting for 29.5% of the sample. The elderly patients were predominantly male, white, retired, and literate. Elderly ESRD patients had a slightly higher frequency of undernourishment and a lower frequency of obesity than the non-elderly adults. A higher frequency of elderly patients were from the South and Southeast regions. The dialysis treatment of patients from both groups was predominantly funded by the public system, but the percent of non-public funding was higher for the elderly group. The most used initial access in the elderly was the central venous catheter and hemodialysis was the main modality at the beginning of treatment (93.2%), as well as during maintenance therapy (91.8%). Advanced age was associated with greater use of central venous catheter in the first dialysis session. The survival of the elderly on dialysis was lower than that of the non-elderly early in the course of dialysis and this difference increased over time. This is yet the largest national epidemiological study of elderly people on chronic dialysis.
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