The purpose of this study is to investigate the relationship between gingival discoloration and Ag2S. Minute granules of dental alloys were embedded in the gingiva during a 5-11 months span, and ...their histological and colorimetric analyses were undertaken. Results showed the following; 1. Cases of low melting silver alloy, 12% Au-Ag-Pd alloy, and Ni-Cr alloy all resulted in gingival discoloration, but it did not occur during the specified experimental period. 2. Regardless of the size of the granules or time, the electron microanalyser showed no signs of sulfer detection in cases of low melting silver alloy. However, in the case of 12% Au-Ag-Pd alloy, sulfer was detected 5 months later for only those granules having the size of 0.2-0.3μm. No surfer was detected in cases of Ni-Cr alloy. 3. Although no proliferation of inflammatory cells were observed around those areas surrounding the 12% Au-Ag-Pd alloy granules, they appeared in cases of the low melting silver alloy and Ni-Cr alloy.
From the standpoint of diagnosing the condition of the gingiva as well as esthetics, gingival color is found to play an important role in dentistry. Thus, it is important to be able to differentiate ...the changes in color of the portion of gingiva which is in contact with the crown. We the authors of this report, decided to measure the gingival color and make basic investigations pertaining to the conditions in relation to color measurements. The results revealed the following. It was possible to accurately measure the marginal and papillary gingiva using the modified version of the CD-270 colorimeter, which is considered to be one of the most accurate source of equipement in differentiating color shade. The detectable color differentiation limit among the dentist of our department was found to be 1.12. The fixation apparatus for the colorimeter was found to show stable and repeatable data. It was possible to be able to control the color difference below the afore mentioned detectable color differentiation limit value by a constant color setting established by our department.
The clinical efficacy and the safety of CS-807, a new oral cephalosporin, were studied in 16 patients with bacterial respiratory tract infections. The results obtained were as follows; 1) Efficacy of ...fourteen patients with respiratory tract infections were estimated. Six of these cases were suffering from bacterial pneumonia, 1 from mycoplasma pneumonia, 2 from an acute exacerbation of chronic bronchitis, 2 from a secondary infection of bronchiectasis and also secondary infection of each one from idiopathic interstitial pneumonia, chronic pulmonary emphysema and bronchial asthma. 2) Two cases were excluded because one was severe underlying disease and the other was symptom of infection was unclear. Isolated organisms were S. pneumoniae (3), S. aureus (1), H. influenzae (3) and P. aeruginosa (1). All strains except one strain of P. aeruginosa were eradicated. 3) Clinical response was good in 11, fair in 2, poor in 1 and unknown in 2 cases. 4) No adverse reactions were observed, but elevation of platelet, mild eosinophilia and transient elevations of serum GPT, BUN and creatinine value were observed in respective patient. From the above results, CS-807 is considered to be useful oral antibiotic for the treatment of the patients with the respiratory tract infections.
Clinical efficacy of 6315-S (flomoxef), a new oxacephem antibiotic, was evaluated in 26 patients with respiratory tract infections: 20 with bacterial pneumonia, 3 with bacterial, bronchitis, one each ...with secondary infection of chronic obstructive lung disease (type B), mycoplasma pneumonia and atypical pneumonia. Response was excellent in 2 patients, good in 13, fair in 7, poor in 3 and undetermined in 1. Causative organisms, were 1 strain of S. aureus, 2 of H. influenzae, 3 of K. pneumoniae (including 1 case each of mixed infection with E. faecalis and E. cloacae), and I mixed infection of C. freundii and E. cloacae. Bacteriological efficacy was observed in only 5 cases. In 2 strains of H. influenzae, 1 was eradicated and 1 decreased, 1 strain of C. freundii mixed with E cloacae was eradicated; 1 strain of K. pneumoniae was replaced by E. aerogenes: and 1 case of mixed infection (K. pneumoniae+E. faecalis) was replaced by P. aeruginosa. As adverse reactions, exanthema was observed in 1 patient. As abnormal laboratory findings, GOT, GPT and Al-P were elevated in 8 patients, and WBC decreased in 2.
PDF
