Uznapredovala liberalizacija tržišta sve je veći izazov sustavima upravljanja kakvi se primjenjuju u javnim poduzećima. Javlja se potreba za organizacijskim i procesnim preustrojem u tri područja: ...strukture grupe, sustavi upravljanja i organizacija za upravljanje/financijsku analizu i praćenje. Za tvrtke u ovom sektoru bitno je da sustavno podižu razinu svojih sustava upravljanja te da usvoje najviše međunarodne standarde. No jednako je važna temeljito upravljanje promjenama kako bi se osigurala puna provedba izrađenih strategija. U ovom se članku istražuje što se može učiniti u tri spomenuta područja kako bi se osiguralo da se javnim poduzećima upravlja u skladu s najnovijim dostignućima. Teorija se potom konkretizira primjenom jednog stvarnog slučaja – riječ je o novijem projektu što ga tvrtka Roland Berger vodi za jedno srednjoeuropsko javno poduzeće.
Hepatitis A viral infection usually lasts up to 12 weeks, but in 3-16% of patients relapses may occur and the course of the disease is protracted. The outcome of hepatitis A is always good, so that ...antiviral therapy is not necessary. However, from the aspect of patients with protracted course of the disease up to a year, it might be important to restore clinical recovery in a shorter period of time. Knowing about antiviral and immunomodulatory effects of endogenous interferon (virally activated) in treatment of protracted hepatitis A, we introduced interferon-alpha in the 12th week of the disease and followed-up its effects on the further course of the disease. The study comprised 80 patients with established diagnosis of acute protracted hepatitis A, excluding hepatitis B, Epstein-Barr, cytomegalovirus, adenovirus or toxic liver lesion. In 40 patients treated with interferon we followed up the activity of aminotransferases and persistence of IgM-anti-HAV in correlation with the same parameters in 40 patients treated symptomatically. The registered persistence of aminotransferases' pathological activity was 20:30 weeks (interferon: symptomatic therapy). In greater doses interferon affected the length of persistence IgM-anti-HAV, 20:34 weeks (interferon: symptomatic therapy).
