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  • Lipoprotein(a) in atheroscl... Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement
    Kronenberg, Florian; Mora, Samia; Stroes, Erik S G ... European heart journal, 10/2022, Volume: 43, Issue: 39
    Journal Article
    Peer reviewed
    Open access

    Abstract This 2022 European Atherosclerosis Society lipoprotein(a) Lp(a) consensus statement updates evidence for the role of Lp(a) in atherosclerotic cardiovascular disease (ASCVD) and aortic valve ...
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  • Familial Hypercholesterolemia: JACC Focus Seminar 4/4
    Brandts, Julia; Ray, Kausik K Journal of the American College of Cardiology, 11/2021, Volume: 78, Issue: 18
    Journal Article
    Peer reviewed

    Detecting familial hypercholesterolemia (FH) early and "normalizing" low-density lipoprotein (LDL) cholesterol values are the 2 pillars for effective cardiovascular disease prevention in FH. ...
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  • Novel and future lipid-modulating therapies for the prevention of cardiovascular disease
    Brandts, Julia; Ray, Kausik K Nature reviews cardiology, 09/2023, Volume: 20, Issue: 9
    Journal Article
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    Lowering the levels of LDL cholesterol in the plasma has been shown to reduce the risk of atherosclerotic cardiovascular disease (ASCVD). Several other lipoproteins, such as triglyceride-rich ...
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  • Low-density lipoproteins ca... Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel
    Ference, Brian A; Ginsberg, Henry N; Graham, Ian ... European heart journal, 08/2017, Volume: 38, Issue: 32
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    Open access

    To appraise the clinical and genetic evidence that low-density lipoproteins (LDLs) cause atherosclerotic cardiovascular disease (ASCVD). We assessed whether the association between LDL and ASCVD ...
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  • Safety and Efficacy of Bemp... Safety and Efficacy of Bempedoic Acid to Reduce LDL Cholesterol
    Ray, Kausik K; Bays, Harold E; Catapano, Alberico L ... New England journal of medicine/˜The œNew England journal of medicine, 03/2019, Volume: 380, Issue: 11
    Journal Article
    Peer reviewed
    Open access

    Short-term studies indicate that bempedoic acid, an ATP citrate lyase inhibitor, reduces LDL cholesterol levels. In a 1-year trial, bempedoic acid added to maximally tolerated statin therapy did not ...
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  • Inclisiran for the Treatmen... Inclisiran for the Treatment of Heterozygous Familial Hypercholesterolemia
    Raal, Frederick J; Kallend, David; Ray, Kausik K ... New England journal of medicine/˜The œNew England journal of medicine, 04/2020, Volume: 382, Issue: 16
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    Open access

    This phase 3 trial evaluated the safety and efficacy of inclisiran, a small interfering RNA that inhibits hepatic PCSK9 synthesis, in 482 adults with heterozygous familial hypercholesterolemia, who ...
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  • Pharmacological lipid-modif... Pharmacological lipid-modification therapies for prevention of ischaemic heart disease: current and future options
    Ray, Kausik K; Corral, Pablo; Morales, Enrique ... Lancet, 08/2019, Volume: 394, Issue: 10199
    Journal Article
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    Open access

    Atherosclerosis and its clinical manifestation as ischaemic heart disease remains a considerable health burden. Given that many factors contribute to ischaemic heart disease, a multifactorial ...
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  • Legacy benefits of blood gl... Legacy benefits of blood glucose, blood pressure and lipid control in individuals with diabetes and cardiovascular disease: Time to overcome multifactorial therapeutic inertia?
    Khunti, Kamlesh; Kosiborod, Mikhail; Ray, Kausik K. Diabetes, obesity & metabolism, June 2018, 2018-06-00, 20180601, Volume: 20, Issue: 6
    Journal Article

    Cardiovascular disease is a major cause of morbidity and mortality globally and the largest contributor to healthcare costs. There is good evidence that management of risk factors such as blood ...
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