Highlights • Oral candidiasis increased with age of 13.2% to 33.3% between 60 and >80 years. • Frequency of colonizing the oral cavity increased with age. • The frequency of oral colonization by ...multi-species of Candida increases with age. • The oral Candida albicans isolates shows increased resistance to fluconazole with increasing age range in older mexican women.
To assess oral signs, symptoms and oral lesions (OL) type and prevalence, in diabetic patients with end stage renal disease (ESRD DM), and compare them with analogous findings in a non-ESRD DM group; ...analyze the possible association between oral manifestations, as well as with relevant laboratory findings. Research design. Two adult groups were studied: Group A: ESRD DM on dialysis, and group B: non-ESRD DM (serum creatinine <2.0 mg/dl). Known DM evolution time, dialysis treatment type and duration, and laboratory results were recorded. An oral exam was performed, searching for signs, symptoms and ESRD-associated OL. Associations were analyzed using Chi square, Fisher s exact test, and odds ratios (OR) with 95% confidence intervals. Ages, time on dialysis, and laboratory results were compared with Student s t test.
229 individuals were examined, group A 99, and group B 130 pts. Signs and symptoms prevalence was higher in group A: 77.8% vs. 57.6%, (P<0.001), uremic breath (48.5%), unpleasant taste (45.5%) and xerostomia (44.4%) being the most frequent ones. OL were also more prevalent in group A; 65.6% vs. 36.9% (P<0.001). The most frequent OL were dry, fissured lips (28.3%), saburral tongue (18.2%) and candidiasis (17.2%). No difference was found in candidiasis prevalence between groups. Candidiasis was found associated to xerostomia (P<0.05) and smooth tongue (P<0.05) only in group A.
ESRD DM patients had a significantly higher prevalence of signs, symptoms and OLs, as compared to non-ESRD DM pts. The high prevalence of uremic fetor, xerostomia, saburral tongue and candidiasis in group A, could be tried as warning signs on the possibility of non diagnosed advanced renal disease in other diabetic patients.
Abstract We analyzed 2378 respiratory samples of children <5 years of age admitted during a 7-year period in order to determine the contribution of seasonal influenza as a cause of hospitalizations, ...as well as the impact of the inclusion of influenza vaccine in the childhood immunization program. The presence of influenza virus was demonstrated in 106 (4.4%) samples. The proportion of influenza hospitalizations after the introduction of influenza vaccination was lower (3.4%) than before the establishment of this vaccination program (7.5%; P = 0.00002). Our study shows that influenza vaccination programs in children significantly reduce the impact of influenza related hospitalizations.
A pesar del gran número de productos disponibles para la limpieza de prótesis dentales, el 60% de los portadores hace uso de ellos, posiblemente por la situación económica. El objetivo fue determinar ...la susceptibilidad antifúngica in vitro que presenta Candida y sus especies a tres sustancias utilizadas para la desinfección de prótesis (hipoclorito de sodio, ácido acético y solución de superoxidación). Se obtuvieron aislados clínicos de Candida de pacientes portadores de prótesis diagnosticados con estomatitis protésica, para su posterior estudio de susceptibilidad in vitro a las diferentes sustancias. El hipoclorito de sodio al 0,5% mostró in vitro una mayor inhibición para las cepas de Candida albicans y Candida no albicans. El ácido acético y la solución de superoxidación no mostraron inhibición in vitro frente a ambas cepas. El hipoclorito de sodio al 0,5% tiene un efecto inhibitorio in vitro sobre las cepas de C. albicans y Candida no albicans.
Orosomucoid-1 Expression in Ameloblastoma Variants García-Muñoz, Alejandro; Bologna-Molina, Ronell; A Rodríguez, Mario ...
International journal of molecular and cellular medicine,
2016, Volume:
5, Issue:
1
Journal Article
Open access
Odontogenic tumors constitute a group of heterogeneous lesions of benign and malignant neoplasms with variable aggressiveness. Ameloblastomas are a group of benign but locally invasive neoplasms that ...occur in the jaws and are derived from epithelial elements of the tooth-forming apparatus. We previously described orosomucoid-1 protein expression in odontogenic myxomas. However, whether orosomucoid-1 is expressed in other odontogenic tumors remains unknown. Since orosomucoid-1 belongs to a group of acute-phase proteins and has many functions in health and disease, we identified and analyzed orosomucoid-1 expression in ameloblastoma variants and ameloblastic carcinoma using western blot and immunohistochemical techniques. Thirty cases of ameloblastoma were analyzed for orsomucoid-1; five specimens were fresh for western blot study (four benign ameloblastomas and one ameloblastic carcinoma), and 25 cases of benign ameloblastoma for immunohistochemical assays. Orosomucoid-1 was widely expressed in each tumor variant analyzed in this study, and differential orosomucoid-1 expression was observed between benign and malignant tumor. Orosomucoid-1 may play an important role in the behavior of ameloblastomas and influence the biology and development of the variants of this tumor.
La caries es la enfermedad bucal más frecuente a nivel mundial. Se origina por una producción excesiva de ácido, que se forma cuando las bacterias que colonizan la boca digieren los azúcares ...presentes en la dieta. Sin embargo, existen azúcares que las bacterias orales no pueden digerir, que son conocidos como prebióticos. Los prebióticos son compuestos que pueden ser utilizados selectivamente por los microorganismos del huésped, en especial los intestinales, y le confieren un beneficio para su salud. Se encuentran presentes de forma natural en alimentos como la leche, miel de abeja, hortalizas, verduras, frutas, cereales, legumbres y frutos secos; también se pueden obtener mediante síntesis química o enzimática. En los últimos años, han surgido nuevas estrategias terapéuticas y preventivas para la caries, enfocadas en utilizar prebióticos en productos de higiene oral, alimentos y suplementos; sin embargo, no se trata de una práctica común en la odontología. Es importante conocer más acerca del beneficio que los prebióticos ofrecen a la salud oral de los individuos, para favorecer su utilización de manera rutinaria como complemento a los tratamientos dentales.
Los enjuagues bucales son soluciones que se emplean después del cepillado para eliminar las bacterias que causan la caries, la inflamación de las encías y el mal aliento, con la finalidad de mantener ...la boca limpia y sana. Sin embargo, en ocasiones, la falta de conocimiento del consumidor deriva en el abuso en su empleo, lo que provoca una serie de efectos adversos que deben ser conocidos por los usuarios. Los medios de comunicación juegan un papel muy importante para que la población utilice los enjuagues bucales y los odontólogos, en algunos casos, los recetan a sus pacientes, junto con el cepillado dental, para el tratamiento de enfermedades. El objetivo del artículo es mostrar a la población los tipos de enjuagues bucales que existen en el mercado, cómo funcionan, y sus ventajas y desventajas, con la finalidad de evitar su uso indiscriminado. Además, se discute sobre el empleo de bacterias “buenas” como auxiliares en la higiene bucal. Esta nueva terapia ha demostrado ser segura y eficaz por lo que probablemente en poco tiempo estará disponible en el mercado.
To estimate and compare periodontal disease prevalence (PD) in two groups of patients with type 2 diabetes (T2D), with and without end stage renal disease (ESRD) and dialysis.
Using a cross sectional ...design, two groups of patients with type 2 diabetes were examined in two general hospitals belonging to Instituto Mexicano del Seguro Social in San Luis Potosí. Group A were patients with ESRD and dialysis; Group B, patients with serum creatinine < 2.0 mg/dL. The WHO Community Periodontal Index (CPI) was used to assess PD. 233 patients were examined among which 172 had functional tooth, suitable for PD evaluation.
71 patients integrated group A; their mean age was 56.2 +/- 11.8 years. 101 patients integrated group B, their mean age was 56.7 +/- 11.9 years (p = 0.768). Elapsed time from T2D diagnosis was 221 +/- 86 months for group A, and 126 +/- 101 months for group B (p < 0.001). Poor oral hygiene was found in 39.8 % of group A patients, and 34.6 % of group B patients (p = 0.133). PD prevalence, with CPI scores 3 and 4, was 63.4 % for group A, and 72.3 % for group B (p = 0.216). Multiple linear regression analysis found PD severity associated to ageing (p < 0.001), poor oral hygiene (p < 0.001) and for group A a shorter time from T2D diagnosis to ESRD (p = 0.0315). ESRD hemodialysis patient's PD was more severe than that of peritoneal dialysis patients (p < 0.03).
both groups had high prevalence of PD and poor oral hygiene. Patients treated with haemodialysis had more severe PD than peritoneal dialysis patients. A shorter time from DM diagnosis to ESRD was found associated to more severe PD.
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