We aimed to evaluate the reproducibility and validity of the newly developed FFQ for the Korean National Health and Nutrition Examination Survey (KNHANES) and to estimate the measure's calibration ...factors.
The 109-item FFQ was administered twice, approximately 9 months apart. We also collected four seasonal 3 d dietary records (DR) as a reference method. Correlation coefficients and joint classification were computed to compare intakes of energy, thirteen nutrients and eleven food groups between the two FFQ to evaluate reproducibility. For validity, de-attenuated and energy-adjusted correlation, joint classification and Bland-Altman statistics were calculated for energy and nutrients between the first FFQ and the DR. To calibrate the FFQ, we performed a linear regression analysis in which the DR were the dependent variables and FFQ, age and sex were the independent variables.
Seoul metropolitan area, Republic of Korea.
A total of 126 adults aged 20-65 years.
The average correlation coefficients measuring reproducibility were 0·54 for nutrients and 0·57 for food groups. The mean correlation coefficient measuring validity was 0·40 for all nutrients between the first FFQ and the DR. On average, 75 % of the participants were classified into the same or adjacent quartiles, while 5 % of the participants were grossly misclassified. The mean energy and nutrient intakes estimated by the calibrated FFQ were similar to the means estimated by the DR.
The newly developed FFQ for assessing dietary intake in the KNHANES has acceptable reproducibility and modest validity compared with a 12 d DR collected over a 9-month period.
We aimed to estimate the annual direct medical costs of South Korean systemic lupus erythematosus (SLE) patients, and their predictors. The 2010 annual direct medical costs of SLE patients in the ...Hanyang BAE Lupus cohort in South Korea were assessed. The information was taken directly from the hospital database and medical records, and included clinical characteristics, disease activity, organ damage, and healthcare utilization. Cost predictors were estimated with a multivariate linear regression model. A total of 749 SLE patients (92.7 % female, mean age 35.7 ± 11.3 years, mean disease duration 9.6 ± 4.9 years) were studied. Their mean annual direct medical costs amounted to USD 3305. The largest component of these costs was the cost of medication (USD 1269, 38.4 %), followed by those of diagnostic procedures and tests (USD 1177, 35.6 %). Regression analysis showed that adjusted mean SLE disease activity index score (
p
< 0.0001), systemic damage index (
p
< 0.0001), and renal (
p
= 0.0039) and hematologic (
p
= 0.0353) involvement were associated with increased direct medical costs, whereas longer disease duration was associated with lower direct medical costs. Greater disease activity and greater organ damage predict higher costs for South Korean SLE patients. Major organ involvement such as renal disorder and hematologic involvement also predicts higher costs, whereas longer duration of disease predicts lower costs.
Objectives The object of this study was to introduce the KORean Observational study Network for Arthritis (KORONA) registry with an emphasis on the design of the Korean rheumatoid arthritis (RA) ...national database, as well as to provide an overview of the RA patients who are currently registered in KORONA. Methods The KORONA was established in July 2009 by the Clinical Research Center for Rheumatoid Arthritis (CRCRA) in South Korea. KORONA is based on a prospective protocol and standard, defined data collection instruments. Demographic and clinical features, laboratory and radiologic data, health-related outcomes, treatment side effects, resource utilization, and health behaviors of the RA cohort patients are recorded in a database. Results A total of 23 institutions, which are about 38% of the rheumatologic departments at tertiary academic hospitals across South Korea, are part of KORONA. The quality control of data collection and management has been performed through annual monitoring and auditing, staff training, and providing standard operation protocol by the executive committee of CRCRA. As of 31 December 2010, 4721 patients with established RA were included in KORONA, because an annual survey had started to be performed in July 2010. Conclusions KORONA is the first nationwide Korean RA-specific cohort and it will provide valuable “real-world” information for Korean RA patients.
Objective: To identify the level of agreement between patients with rheumatoid arthritis (RA) and physicians in the global assessment of disease activity and to explore factors influencing their ...discordance.
Methods: A total of 4368 patients with RA were analyzed from the KORean Observational study Network for Arthritis (KORONA) database. Patients were divided into four subgroups according to difference from their physicians in the assessment of disease activity by substracting physician's visual analog scale (VAS) from patient's VAS as follows: positive discordance group I (10 mm ≤ discordance <25 mm), positive discordance group II (≥25 mm), concordance (<|10| mm), and negative discordance (≤ −10mm). Multinomial logistic regression analysis was performed to identify factors associated with discordance.
Results: Only 1350 (29.2%) patients were classified in the concordance group. Positive discordance was found in 52.3% of the patients (n = 2425), with 33.7% (n = 1563) showing marked discordance (≥25 mm). The high disease activity (OR =1.41), gastrointestinal (GI) disease (OR =1.28), pain (OR =1.12), fatigue (OR =1.07) were consistently associated with positive discordance.
Conclusion: More than half of patients with RA thought their disease more severe than their physicians. In addition to high disease activity, pain, fatigue, and sleep disturbance or GI disease were associated with the discordance between physicians and patients with RA.
The Assessment for Nutrient Intakes of Korean Patients with Heart Failure Lee, H.R., Korea University, Seoul, Republic of Korea; Kang, B.R., Korea University, Seoul, Republic of Korea; Chung, H.K., Youngdong Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea ...
Hanʼguk yongyang hakhoe chi,
(Jun 2010), Volume:
43, Issue:
3
Journal Article
The prevalence of heart failure (HF) is increasing globally and growing evidence has shown that dietary factors play an important role in preventing and improving prognosis of HF. However, little ...data on nutrient intake in Korean HF patients which are available to develop dietary guidelines for HF. The aims of this study were to estimate nutrient intake in 78 HF patients and evaluate whether the estimated nutrient intake is appropriate compared to dietary reference intake for Koreans. Data are presented as the ratio of actual intake and estimated average requirement (EAR) for each nutrient. The result showed that the average nutrient intakes including total energy and protein met EAR in total patients. However, the deficiencies in mineral and vitamin intakes were found. Moreover, the proportion of subjects with lower intake than EAR was substantial. The results showed that the proportion of male HF patients with inferior intakes to EAR in calcium, potassium (compared to adequate intake: AI), folate and vitamin B∧12 were 38%, 79%, 38%, and 65%, respectively. Also, the proportion of female HF patients with inferior intakes to EAR in calcium, potassium (compared to AI), folate and vitamin B∧12 were 35%, 88%, 38% and 40%, respectively. In particular, the elderly with HF (greater-than or equal to 70 yrs, n = 28) showed more serious deficiencies in calcium, potassium (compared to AI), folate and vitamin B∧12. In summary, the intakes of potassium, calcium, folate, and vitamin B∧12 were not sufficient to meet EAR in HF patients. Furthermore, the proportions of subjects with lower intake than EAR in these nutrients were substantial, raising the possibility that these micronutrients may be involved in the pathogenesis of HF. Practical dietary guideline for HF patients is needed to improve prognosis of HF.
가계금융조사를 활용한 단위무응답 조정효과 분석 백지선; Jeeseon Baeka; 심규호 ...
Ŭngyong tʻonggye yŏnʼgu,
2013, Volume:
26, Issue:
3
Journal Article
Open access
통계조사에서 단위 무응답은 표본크기를 축소시켜 추정값의 효율을 떨어뜨릴 뿐만 아니라, 주요 관심변수에 대해 응답자와 무응답자간의 차이가 존재하는 경우 무응답 편향(bias)을 발생시키는 요인으로 일반적으로 가중값 조정방법을 이용하여 보정한다. 대부분의 조사에서 무응답 표본에 대한 정보를 얻는 것은 현실적으로 매우 어려우며, 무응답으로 인한 추정값의 편향 ...정도를 파악하는 것 또한 쉽지 않다. 통계청에서는 2010년, 2011년 가구패널조사인 가계 금융조사를 실시하였다. 2010년 1차 웨이브는 1만 가구에 대해 모두 응답한 정보를 가지고 있으며, 2011년 2차 웨이브에는 부재, 거부 등으로 인한 무응답 표본(약 10%)이 존재한다. 본 연구에서는 2차 웨이브의 무응답 표본들을 무응답 성향이 강한 표본으로 가정하고 1차 웨이브에서 무응답가구로 분류한 후 무응답 가구의 특성과 무응답 편향 정도 및 무응답 조정 효과를 분석하였다.
Unit non-response of surveys reduces the efficiency of the estimates and also causes non-response bias especially when there is large difference between respondents and non-respondents. Non-response weighting adjustments have usually been used to compensate for non-response. It is not easy to examine the nonresponse bias as well as to obtain information on the non-respondents in sample surveys. A household panel survey, called The Survey of Household Finances, was conducted in both 2010 and 2011. In this paper, we assume that non-response households in Wave 2 have strong non-response (non-cooperative) tendency. We classify those households into non-response households in Wave 1. Under this assumption, the characteristics of non-response households, the non-response bias and the effect of non-response adjustments are investigated.