Ananas comosus, conocido popularmente como piña, tiene una anatomía de planta bien definida y numerosos fitoquímicos farmacológicamente activos. Algunos de éstos son responsables del potencial ...antimicrobiano de la especie, que ha sido ampliamente estudiado dada la resistencia bacteriana a los antibióticos actualmente utilizados. Teniendo esto en cuenta, se define que la característica principal de un medicamento es la ausencia de efectos tóxicos, por lo tanto, es necesario buscar datos sobre la toxicidad de A. comosus, colaborando para su posible uso como fármaco. Comparando extractos hidroalcohólicos de las hojas de la corona, cáscara y pulpa de la infrutescencia, fue posible determinar que los tres extractos probados no son tóxicos, siendo el de menor toxicidad para Artemia salina Leach (extracto de hojas con CL50 igual a 994 μg/mL) y a sangre de cordero (extracto de pulpa con porcentaje de hemólisis igual a 0,83%). Los estudios sobre principios y metodologías similares a los utilizados aquí han encontrado resultados comparables que indican la baja toxicidad de la planta. Estos resultados aportan a las investigaciónes que promueven el uso de la piña como agente fitoterapéutico y reafirman su presencia en el Sistema Único de Salud de Brasil.
O presente estudo foi realizado com o objetivo de investigar sobre a deficiência intelectual, e o trabalho que vem sendo realizado na Educação Infantil e Anos Iniciais do Ensino Fundamental. Para ...tanto, se fez necessário abordar primeiramente sobre a história da Educação Inclusiva, descrevendo suas fases, bem como, relatando sobre a educação inclusiva no Brasil. Em seguida, foi descrito a respeito da percepção de Educação Inclusiva como forma de nortear esta pesquisa, para posteriormente discorrer sobre a deficiência intelectual, tendo como objetivo principal o processo de ensino e aprendizagem do educando com deficiência intelectual. Finalizando com o trabalho com deficiência intelectual na Educação Infantil e no ensino Fundamental I. A metodologia utilizada foi pesquisa qualitativa com enfoque bibliográfico evidenciando como vendo sendo realizado o trabalho com alunos com deficiência intelectual na Educação Infantil e Anos iniciais do Ensino Fundamental. Ao final da pesquisa pode-se concluir que a educação inclusiva somente acontecerá se houver uma escola adequada, comprometida e empenhada com os educandos com deficiência intelectual, fazendo dessa forma uma inclusão com responsabilidade.
Purpose: This work examines the role of Leadership in the Public Sector, with a focus on the leaders' interaction with their teams, aiming to build a harmonious interpersonal relationship to ensure ...successful management. This, in turn, allows for the creation of management with a predominantly democratic character, with the potential to address both local and societal needs. In this context, it is emphasized that motivation is something intrinsic to each individual, and the leader must have the potential to stimulate it. The general objective of this work is to analyse the importance of leadership in improving the performance of employees in the context of Public Health. Theoretical Framework: Leadership permeates all managerial activities and is not an isolated activity. Its importance is underestimated when judged solely in terms of the proportion of managerial activities that are strictly related to team management. Method/design/approach: This research is exploratory in nature, as it conducted a literature review on the role of leadership in public institutions, using various publicly available sources such as books, journals, theses, internet articles, and monographs. Results and conclusion: The coordinator and 10 employees from various positions out of the total of 40 were selected to participate in the research. It is noteworthy that the leader holds a degree in Pedagogy and is currently pursuing Nursing, is 34 years old, female, and has previously served as a coordinator in the same UBS for 4 years in the recent past, marking her first leadership experience at the age of 26. Currently, she leads a team of 40 people. Research implications: The research emphasizes the creation of a management with a democratic predominance. If the results indicate that leadership plays a significant role in this aspect, it may influence management practices in healthcare units and potentially in other public sector organizations. Originality/value: The research focuses on the field of Public Health, which can be considered original, as it is a specific and critical area of the public sector that is not frequently addressed in general leadership studies.
The aims were to evaluate the effect of breed on the genetic polymorphism kappa-casein, physicochemical composition of milk and Coalho cheese, and on cheese yield; and to evaluate the effect of ...different periods of storage on sensorial acceptance of the Coalho cheese obtained from milk of Guzerat, Gyr and Sindi cows. Twenty (20) cows of Zebu breeds were selected, from which it was obtained the frequency values of the genetic polymorphism kappa-casein. Milk were submitted to fat, protein, lactose, non-fat solids and total solids, electrical conductivity analysis and somatic cell count. Cheeses were submitted to fat, protein, total solids, pH, moisture and yield (g TS/L) analysis. Attributes appearance, aroma, texture and flavor were judged at the 1st, 25th and 46th day of storage. There was a total frequency of 0.70 for genotype AA, 0.30 for genotype AB. There was no significant difference in milk composition among the studied breeds. However, there were differences in the physicochemical composition (with the exception of the protein) and the yield of the cheeses, but all the breeds showed a similar real yield. It was found effect of the storage period on the cheeses sensory attributes in the different breeds, with the exception of the appearance. The milk of the Guzerat, Gyr and Sindi breeds constitute an excellent raw material for the production of curd cheese and ensures a satisfactory sensorial acceptance of the product at the 1st, 25th and 46th days of storage.
Objetivo: Este trabalho analisa o papel da Liderança no Setor Público, com destaque para a atuaçâo dos líderes frente à sua equipe, buscando construir urna relaçâo interpessoal hannoniosa para que a ...gestâo seja exitosa, o que pennitirá que se crie urna gestâo com predominância democrática, com potencial para atender os anseios tanto local quanto social. Neste contexto, ressalta-se que a motivaçâo é algo que já está no íntimo de cada pessoa, sendo que o líder deve ter potencial para estimulá-la. O objetivo geral deste trabalho é analisar a importáncia da liderança na melhoria do desempenho dos colaboradores no contexto da Saúde Pública. Referencial teórico: A liderança penneia todas as atividades gerenciais e nâo é urna atividade isolada. Sua importáncia é subestimada quando julgada apenas em tenno da proporçâo das atividades gerenciais que estáo estritamente relacionadas coin a conduçâo da equipe de trabalho. Método: Esta pesquisa apresenta-se como exploratoria, pois fez um levantamento bibliográfico sobre o papel da liderança nas repartiçôes públicas, utilizando como instrumentos várias bibliografías encontradas em dominio público como: livros, revistas, monografías, teses, artigos de internet. Resultados e conclusâo: Forain escollados a coordenadora e 10 funcionários de cargos diversos do total geral de 40, para participarem da pesquisa. Ressalta-se que a líder tem fonnaçâo superior em Pedagogía e está cursando Enfermagem, tem 34 anos, do sexo feminino, e já foi coordenadora da mesma UBS durante 4 anos em passado próximo, a sua primeira experiéncia como líder, coma idade de 26 anos. Atualmente, lidera 40 pessoas. Implicaçôes da pesquisa: A pesquisa enfatiza a criaçâo de urna gestâo com predominância democrática. Se os resultados indicarem que a liderança desempenha um papel significativo nesse aspecto, isso pode influenciar as práticas de gestâo em unidades de saúde e, potencialmente, em outras organizaçôes do setor público. Originalidade/valor: A pesquisa se concentra na área da Saúde Pública, o que pode ser considerado original, urna vez que esse é um campo específico e crítico do setor público que nâo é frequentemente abordado em estudos gérais de liderança.
Los objetivos fueron evaluar el efecto de la raza sobre el polimorfismo genético de la kappa-caseína, la composición fisicoquímica de la leche y del queso Coalho, y el rendimiento del queso, así como ...evaluar el efecto de diferentes periodos de almacenamiento sobre la aceptación sensorial del queso Coalho obtenido a partir de leche de vacas Guzerat, Gyr y Sindi. Se seleccionaron veinte (20) vacas de razas cebú y se obtuvieron sus valores de frecuencia del polimorfismo genético de la kappa-caseína. La leche se sometió a un análisis de grasa, proteína, lactosa, sólidos no grasos y sólidos totales, conductividad eléctrica y cuenta de células somáticas. Los quesos se sometieron a análisis de grasa, proteína, sólidos totales, pH, humedad y rendimiento (g ST/L). Se evaluaron los atributos apariencia, aroma, textura y sabor en los días 1, 25 y 46 de almacenamiento. La frecuencia total fue de 0.70 para el genotipo AA y 0.30 para el genotipo AB. No hubo diferencias significativas en la composición de la leche entre las razas estudiadas. Sin embargo, hubo diferencias en la composición fisicoquímica (exceptuando la proteína) y el rendimiento de los quesos; pero todas las razas mostraron un rendimiento real similar. El periodo de almacenamiento tuvo efectos observables sobre los atributos sensoriales de los quesos en las diferentes razas, con la excepción de su apariencia. La leche de las razas Guzerat, Gyr y Sindi constituye una excelente materia prima para la producción de cuajada y garantiza una aceptación sensorial satisfactoria del producto a los días 1, 25 y 46 de almacenamiento.
The nutraceutical properties of colostrum have stimulated interest in its use in the production of functional foods and supplements that benefit human health. This study investigated the fatty acid ...profile of Greek yogurt formulations added with bovine colostrum. Four formulations of Greek yogurt were developed with different colostrum levels: 0, 10, 20, and 30%. Next, fat extraction and esterification were performed to determine the fatty acid profile. Then, the concentrations of fatty acid methyl esters were determined by gas chromatography. No effect was observed for the C14:0, C16:0, and C18:0 concentrations with the addition of colostrum. Although the C18:1c9, C18:2n6, C18:3n3, and C20:4n6 concentrations were not affected by colostrum, the C16:1c9, polyunsaturated fatty acids, and n-6 fatty acid contents increased, without changes in the n-6 to n-3 ratio. C18:1t9 was the only monounsaturated fatty acid that differed among formulations and it increased with colostrum addition. There was no effect of the colostrum increase on the total saturated, unsaturated, and monounsaturated fatty acid concentrations. The bovine colostrum used as an ingredient in Greek yogurt showed slight changes in the fatty acid profile. The use of colostrum is an alternative to reduce costs and maintain health benefits.
Sepsis is a serious health condition caused by the body's exaggerated response to an infection that influences organ failure and death of individuals, accounting for about 20% of global mortality. ...Early detection of sepsis remains a medical challenge due to heterogeneity in the source of infection. The lack of a specific diagnosis and early predictions make adequate clinical treatment unfeasible and thus leads to a mortality rate. The prediction of sepsis through machine learning models has gained special attention due to the abundance of available data. It is in this context that the present research proposes a hybrid model, composed of a committee of classifiers for the detection of sepsis. For this, we use the PhysioNet database, where we apply the Gaussian distribution to deal with missing data and the SMOTE method for class balancing. We started our experiment in an exploratory way, seeking to identify among nine algorithms which were the most promising to perform the classification tasks. Then, we developed our hybrid model composed of a Light Gradient Boosting, Multilayer Perceptron, Logistic Regression and Random Forest, both acting on a classification committee that reached an accuracy of 95.08%, Kappa of 0.1512, Sensitivity of 0.2868, Specificity of 0.9629 and AUC of 0.7434. Finally, it is worth mentioning that the results obtained are promising and open a range of possibilities for future work.
Indiscriminate use of antimicrobials Silva, Lívia Maria Lucena; Ramos, Vanessa Pauline Rodrigues da Silva; Silva, Lídia Maria Gomes da ...
IJS - International Journal of Sciences,
2022, Volume:
4, Issue:
2
Journal Article
PDF
