Used cooking oil is cooking oil that has been heated repeatedly, so that it can cause the formation of free radical compounds. Free radicals are toxic kidneys that generate cell injury via lipid ...peroxidation, DNA damage, and protein peroxidation. Black tea (Camellia sinensis) infusion has a strong polyphenol group, namely epigallocatechin gallate, thearubigin, theaflavin, the amino acid L-theanine, flavonols, and catechins that can inhibit free radicals and protect organs from oxidative stress. This study was a post-only control group design experiment. The research subjects used were 24 Sprague Dawley male rats which were divided into six groups. The first group was the control group (K0). Treatment group 1 was given distilled water and used cooking oil after 12 times heating (K1), treatment group 2 was given black tea at a dose of 2.5g/ kg bw (body weight) and distilled water (K2), and treatment group 3 was given black tea at a dose of 3.75 g/kg bw and distilled water (K3). Treatment group 4 was given used cooking oil after 12 times heating and black tea with a dose of 0.50 gr/200 gr bw (K4), treatment group 5 was given used cooking oil after 12 times heating and black tea with a dose of 3.75 g/kg bw (K5). All groups were treated for 42 days. Then, the rats' kidney was collected, and data were analyzed by Kruskal Wallis and One Way ANOVA test. The results of the Kruskal Wallis and One Way ANOVA test showed a decrease in glomerular and tubular damage after the rats orally induced with black tea were given 12x heating used cooking oil (p<0.05). The mean histopathological score in the administration of black tea at a dose of 3.75 g/kg bw was lower than at a dose of 2.5 g/kg bw. This study shows that infusion of black tea (Camellia sinensis) can prevent glomerular and tubular damage induced by used cooking oil.
Demam Berdarah Dengue (DBD) merupakan masalah kesehatan yang serius. Pengendalian vektor adalah strategi untuk mengurangi insiden infeksi dan mencegah terjadinya wabah. Penularan DBD dapat terjadi di ...lingkungan sekolah, karena aktivitas menggigit nyamuk vektor DBD adalah siang hari. Data Dinas Kesehatan Kota Bengkulu Tahun 2017 menunjukkan DBD Kecamatan Muara Bangkahulu Kota Bengkulu yang merupakan daerah endemis DBD dan lingkungan kampus Universitas Bengkulu (UNIB) yang memiliki angka kesakitan yang tinggi yaitu 143 kasus per 100.000 penduduk dan memiliki angka Case Fatality Rate (CFR) atau yang meninggal sebesar 15,7% terutama penderita adalah usia sekolah. Sosialisasi ini menerapkan berbagai metode belajar, yaitu kuliah interaktif dan praktik survey entomologi. Penyuluhan diikuti oleh 24 orang guru dari 13 sekolah di sekitar lingkungan UNIB dengan latar belakang pendidikan terakhir terbanyak Sekolah Menengah Atas (SMA) yaitu 87,5%. Hasil dari kegiatan ini guru dapat menjadi duta di sekolah untuk program pengendalian vektor penyakit DBD untuk mengurangi angka kejadian infeksi dan tingkat keparahan DBD. Kontrol vektor tetap menjadi satu-satunya intervensi yang tersedia untuk mencegah dan mengontrol penularan DBD.
Extraction of a plant in traditional medicine is a very crucial stage for the success of the treatment. For example, nangka kuning (Vincetoxicum villosum (Blume) Kuntze) which has been scientifically ...researched, its leaves are extracted with ethanol solvent using the maceration method. Meanwhile, by local people,nangka kuning leaves are processed by boiling using water. This attracted the attention of researchers to re-analyze the content of secondary metabolites in nangka kuning leaf extract made with different solvents and methods. Researchers carried out the extraction using water with heating (infusion), ethanol without heating (maceration) and chloroform without heating (maceration). The results obtained from the three types of extracts contained secondary metabolites of alkaloids in the three extracts. While steroids are only found in extracts with a water solvent. Then the tannins are found in the extract with water and ethanol as solvents. Negative results from the three extracts were shown for secondary metabolites of flavonoids and saponins. So it can be concluded that nangka kuning leaf extract which has the most optimal secondary metabolite is the extract using water as a solvent by heating.
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