A
bstract
A search for high-mass dimuon resonance production in association with one or more b quark jets is presented. The study uses proton-proton collision data collected with the CMS detector at ...the LHC corresponding to an integrated luminosity of 138 fb
−
1
at a center-of-mass energy of 13 TeV. Model-independent limits are derived on the number of signal events with exactly one or more than one b quark jet. Results are also interpreted in a lepton-flavor-universal model with Z′ boson couplings to a bb quark pair (
g
b
), an sb quark pair (
g
b
δ
bs
), and any same-flavor charged lepton (
g
ℓ
) or neutrino pair (
g
ν
), with
|g
ν
|
=
|g
ℓ
|
. For a Z′ boson with a mass
m
Z
′
= 350 GeV (2 TeV) and
|δ
bs
|
< 0.25, the majority of the parameter space with 0.0057 <
|g
ℓ
|
< 0.35 (0.25 <
|g
ℓ
|
< 0.43) and 0.0079 < |
g
b
| < 0.46 (0.34 < |
g
b
| < 0.57) is excluded at 95% confidence level. Finally, constraints are set on a Z′ model with parameters consistent with low-energy b → s
ℓℓ
measurements. In this scenario, most of the allowed parameter space is excluded for a Z′ boson with 350 <
m
Z
′
< 500 GeV, while the constraints are less stringent for higher
m
Z
′
hypotheses. This is the first dedicated search at the LHC for a high-mass dimuon resonance produced in association with multiple b quark jets, and the constraints obtained on models with this signature are the most stringent to date.
Ce 140 ( n , γ ) is a key reaction for slow neutron-capture ( s -process) nucleosynthesis due to being a bottleneck in the reaction flow. For this reason, it was measured with high accuracy ...(uncertainty ≈ 5 % ) at the n_TOF facility, with an unprecedented combination of a high purity sample and low neutron-sensitivity detectors. The measured Maxwellian averaged cross section is up to 40% higher than previously accepted values. Stellar model calculations indicate a reduction around 20% of the s -process contribution to the Galactic cerium abundance and smaller sizeable differences for most of the heavier elements. No variations are found in the nucleosynthesis from massive stars. Published by the American Physical Society 2024
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Cyclosporine and tacrolimus, two calcineurin inhibitors, show different side effects and toxicities. The data concerning their nephrotoxicity are few and conflicting. A retrospective study was ...performed in 2 groups of renal transplant recipients treated with cyclosporine or tacrolimus to evaluate graft function and side effects. All patients had completed at least 6 months of follow-up before inclusion in the study. Group I included 10 patients who were converted from cyclosporine to tacrolimus, due to cosmetic problems or due to chronic graft dysfunction with creatinine values <3 mg/dL. After conversion, there was a significant reduction in creatinine values (from 2.43 ± 1.21 to 1.86 ± 0.72 mg/dL;
P = .023) and an improvement in creatinine clearance (from 47.5 ± 19.2 to 56.1 ± 18.9 mL/min;
P = .047). The lipid profile did not change, but there was a trend to better blood pressure control with less antihypertensive drugs. Group II compared 2 subgroups of patients receiving kidneys from the same donor, one treated with cyclosporine and the other with tacrolimus. Tacrolimus patients showed better renal function; namely, creatinine was 1.15 ± 0.27 versus 1.44 ± 0.33 mg/dL (
P = .029) and creatinine clearance was 87.7 ± 27.1 versus 60.3 ± 25.9 mL/min (
P = .043). Lipid and blood pressure values were not different between the 2 subgroups, but tacrolimus patients tended to need a lower number of antihypertensive medications. The incidence of de novo diabetes mellitus was approximately 20% among patients using tacrolimus. We concluded that tacrolimus may be less nephrotoxic than cyclosporine. Tacrolimus patients showed better graft function and easier blood pressure control, but a high incidence of posttransplantation diabetes mellitus.
A
bstract
A search for the production of pairs of heavy Majorana neutrinos (N
ℓ
) from the decays of Z′ bosons is performed using the CMS detector at the LHC. The data were collected in proton-proton ...collisions at a center-of-mass energy of
s
= 13 TeV, with an integrated luminosity of 138 fb
−
1
. The signature for the search is an excess in the invariant mass distribution of the final-state objects, two same-flavor leptons (e or
μ
) and at least two jets. No significant excess of events beyond the expected background is observed. Upper limits at 95% confidence level are set on the product of the Z′ production cross section and its branching fraction to a pair of N
ℓ
, as functions of N
ℓ
and Z′ boson masses (
m
N
ℓ
and
m
Z
′
, respectively) for
m
Z
′
from 0.4 to 4.6 TeV and
m
N
ℓ
from 0.1 TeV to
m
Z
′
/
2. In the theoretical framework of a left-right symmetric model, exclusion bounds in the
m
N
ℓ
-
m
Z
′
plane are presented in both the electron and muon channels. The observed upper limit on
m
Z
′
reaches up to 4.42 TeV. These are the most restrictive limits to date on the mass of N
ℓ
as a function of the Z′ boson mass.
Ischemic heart disease is a clinically relevant entity in both men and women. However, differences have been observed in the pathophysiological mechanism in women, which determine a clinical ...presentation, risk factors and therapeutic treatments that may vary with respect to men. A narrative review has been carried out that reveals these differences in order to carry out a more optimal approach to ischemic cardiomyopathy in women.
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