Existing studies have shown a correlation between leisure activities and depressive symptoms in older adults, but the direction of the longitudinal relationship is inconsistent. This study used an ...autoregressive cross-lagged model to examine the longitudinal relationship between leisure activity participation and geriatric depression.
A total of 7,138 participants aged 60 years or older from the 2nd to the 4th wave of the China Health and Retirement Longitudinal Study (CHARLS) were analysed.
First, present depressive symptoms were significantly associated with future depressive symptoms (β
= .893, p < .001; β
= .946, p < .001), and the same rule applied to leisure activities (β
= .402, p < .001; β
= .404, p < .001). Second, current depressive symptoms negatively predicted future leisure activities (β
= -.071, p < .001; β
= -.085, p < .001), but the inverse relationship was not statistically significant (β
= -.003, p > .05; β
= -.003, p > .05).
These findings underscore the importance of interventions targeting depressive symptoms to potentially enhance engagement in leisure activities among older adults. The results contribute to the understanding of the complex dynamics between mental health and lifestyle choices in older populations, highlighting the potential of proactive mental health interventions to improve overall well-being.
Excessive application of chemical fertilizer has exerted a great threat to soil quality and the environment. The inoculation of plants with plant-growth-promoting rhizobacteria (PGPR) has emerged as ...a great prospect for ecosystem recovery. The aim of this work to isolate PGPRs and highlights the effect of bacterial inoculants on available N/P/K content in soil and on the growth of wheat under conditions of reduced fertilizer application.
Thirty-nine PGPRs were isolated and tested for their growth-promoting potential. Thirteen isolates had nitrogen fixation ability, of which N9 (Azotobacter chroococcum) had the highest acetylene reduction activity of 156.26 nmol/gh. Eleven isolates had efficient phosphate solubilizing ability, of which P5 (Klebsiella variicola) released the most available phosphorus in liquid medium (231.68 mg/L). Fifteen isolates had efficient potassium solubilizing ability, of which K13 (Rhizobium larrymoorei) released the most available potassium in liquid medium (224.66 mg/L). In culture medium supplemented with tryptophan, P9 (Klebsiella pneumoniae) produced the greatest amount of IAA. Inoculation with the bacterial combination K14 + 176 + P9 + N8 + P5 increased the alkali-hydrolysed nitrogen, available phosphorus and available potassium in the soil by 49.46, 99.51 and 19.38%, respectively, and enhanced the N, P, and K content of wheat by 97.7, 96.4 and 42.1%, respectively. Moreover, reducing fertilizer application by 25% did not decrease the available nitrogen, phosphorus, and potassium in the soil and N/P/K content, plant height, and dry weight of wheat.
The bacterial combination K14 + 176 + P9 + N8 + P5 is superior candidates for biofertilizers that may reduce chemical fertilizer application without influencing the normal growth of wheat.
A lysosome-targeting and polarity-specific fluorescent probe CPM has been rationally designed for cancer diagnosis and imaging. We have successfully shown that lysosome polarity may serve as an ...ubiquitious marker for cancer detection. The potential of CPM for cancer diagnosis has also been demonstrated at the levels of live cells, organs, whole animal, and clinical patient tissue samples.
Developing cost-effective electrocatalysts operated in the same electrolyte for water splitting, including oxygen and hydrogen evolution reactions, is important for clean energy technology and ...devices. Defects in electrocatalysts strongly influence their chemical properties and electronic structures, and can dramatically improve electrocatalytic performance. However, the development of defect-activated electrocatalyst with an efficient and stable water electrolysis activity in alkaline medium remains a challenge, and the understanding of catalytic origin is still limited. Here, we highlight defect-enriched bifunctional eletrocatalyst, namely, three-dimensional iron fluoride-oxide nanoporous films, fabricated by anodization/fluorination process. The heterogeneous films with high electrical conductivity possess embedded disorder phases in crystalline lattices, and contain numerous scattered defects, including interphase boundaries, stacking faults, oxygen vacancies, and dislocations on the surfaces/interface. The heterocatalysts efficiently catalyze water splitting in basic electrolyte with remarkable stability. Experimental studies and first-principle calculations suggest that the surface/edge defects contribute significantly to their high performance.
A focused PROTAC library hijacking cancer therapeutic target CDK6 was developed. A design principle as “match/mismatch” was proposed for understanding the degradation profile differences in these ...PROTACs. Notably, potent PROTACs with specific and remarkable CDK6 degradation potential were generated by linking CDK6 inhibitor palbociclib and E3 ligase CRBN recruiter pomalidomide. The PROTAC strongly inhibited proliferation of hematopoietic cancer cells including multiple myeloma and robustly degraded copy-amplified/mutated forms of CDK6, indicating future potential clinical applications.
Overuse of chemical fertilizer and pesticides in agricultural activity is frequently damaging to soil health and can accumulate heavy metals in the soil environment, causing harm to plants, humans, ...and the ecosystem. This study was done to evaluate the effectiveness of biofertilizers in reducing heavy metal levels in contaminated soil and enhancing the activity of soil enzymes that are crucial to plant growth and development. Two bacteria strains, Pseudomonas aeruginosa. and Bacillus firmus, were chosen to develop biofertilizers based on molasses. The pot experiment was setup using a completely randomized design with four treatments and five levels; Bacillus firmus and Pseudomonas aeruginosa were used separately, and they were combined for the biofertilizer dose (20, 40, 60, 80, and 100 mL). Utilizing contaminated soils taken from a greenhouse farm the effect of biofertilizer on heavy metal bioremediation and soil enzyme activity was examined. Methods of soil agrochemical analysis were used to determine the soil physiochemical properties and the concentrations of heavy metals Cu, Fe, Zn, Cd, Mo, Mn, were determined by inductively coupled plasma-mass spectrometry ICP-MS, following DTPA extraction methods. In results, soil pH decreased from 8.28 to 7.39, Ec increased from 0.91 to 1.12, organic matter increased from 18.88 to 20.63 g/kg, N increased gradually from 16.7 to 24.4 mg/kg, and K increased from 145.25 to 201.4 mg/kg. The effect of biofertilizer treatment on soil physiochemical characteristics was significantly positive. Application of biofertilizer significantly increased the heavy metal bioavailability and the activities of soil enzymes. Soil pH were positively correlated with soil Zn (0.99819*), APK (0.95869*) activity and negatively correlated with Fe (0.96759*) also statistically significant at (p < 0.05). The soil Cu positively correlated with Fe (0.99645*), Cd (0.97866*), β.D.GLU (0.99769*) and negatively correlated with PAK (- 0.9624*). Soil ARY had positive correlation with soil Mn (0.99683*), Cd (0.95695*), and negative correlation with PAK (- 0.99424*) at (p < 0.05). Soil enzyme activities were negatively correlated to heavy metals at a significant level. Collectively, the study highlights the potential of biofertilizers as a sustainable and effective approach to enhance soil health and remediate heavy metal-contaminated soils in greenhouses.
Industrial static VAr compensators (SVCs) are typically applied at or near the load center to mitigate voltage fluctuations, flicker, phase unbalance, or other load-related disturbances. In this ...paper, a phase-to-phase "open + close" control scheme for industrial SVC is proposed. The forward loop is to guarantee short response time, while the feedback loop is to ensure good dynamics and steady characteristics of SVC. The fast compensation algorithm for asymmetric industrial loads based on instantaneous reactive power theory is used in the forward loop, while a fuzzy proportional-integral-differential control strategy is applied to the close loop. The hardware and software of this SVC control system is developed based on SIMATIC-TDC and WinCC; the former is the most modern but well-proven industrial controller, while the latter is the globally used human machine interface system. Many industrial applications show that this kind of control system can meet the strict performance and reliability requirements of industrial SVCs.
The depth extent of low velocity fault zones is still a matter of debate due to the lack of vertical resolution for most seismic methods. Autocorrelations and cross-correlations of seismic ambient ...noise provide us new constraints on this issue by obtaining the shallow subsurface reflections without the need of active sources or earthquakes. The horizontal-to-vertical spectral ratio (HVSR) method can also give constraints on this interface and does not need any extra cost of data collection. In this study, we used one-month continuous seismic data from a dense linear array deployed crossing the Chenghai Fault (CHF) in Yunnan, southwest China. Single station autocorrelation and adjacent station pair cross-correlation methods were used to retrieve body wave reflections from the interface of the shallow crustal low-velocity zone (LVZ). The HVSR method was also performed to delineate the shape of the LVZ. Results show an inverted trapezoidal LVZ which extends to ~1.0 km depth across the fault zone with a lateral extent of ~3 km. Previous studies based on ambient noise surface-wave tomography and teleseismic travel time analysis in the same area show similar characteristics, consistent with the interpretation of our results.
•The depth extent of low velocity fault zones is well constrained.•P wave reflections from the interface are retrieved by ambient noise interferometry.•Horizontal-to-vertical spectral ratio are used to co-constrain the interface.•Dense station deployment provides high lateral resolution of the interface.
Periodic wrinkling across different scales has received considerable attention because it not only represents structure failure but also finds wide applications. How to prevent wrinkling or create ...desired wrinkling patterns is non‐trivial because the dynamic evolution of wrinkles is a highly nonlinear problem. Herein, we report a simple yet powerful method to dynamically tune and/or erase wrinkling patterns with visible light. The light‐induced photoisomerization of azobenzene units in azopolymer films leads to stress release and consequently to the erasure of the wrinkles. The wrinkles in unexposed regions are also affected and oriented perpendicular to the exposed boundary during the stress reorganization. Theoretical models were developed to understand the dynamics of the reversible photoisomerization‐induced wrinkle evolution. This method can be applied for designing functional materials/devices, for example, for the reversible optical writing/erasure of information as demonstrated here.
Surface wrinkles on azopolymer films can be optically erased by visible‐light irradiation. The rapid reversible photoisomerization of the azobenzene units generates a significant local nanoscale force throughout the film, which leads to stress release and erasure of the wrinkles. Highly ordered wrinkling patterns with well‐defined microstructures were fabricated by selective light exposure.
Developing a simple and efficient method for removing organic micropollutants from aqueous systems is crucial. The present study describes the preparation and application, for the first time, of ...novel MXene-decorated bismuth ferrite nanocomposites (BiFeO
/MXene) for the removal of six sulfonamides including sulfadiazine (SDZ), sulfathiazole (STZ), sulfamerazine (SMZ), sulfamethazine (SMTZ), sulfamethoxazole (SMXZ) and sulfisoxazole (SXZ). The properties of BiFeO
/MXene are enhanced by the presence of BiFeO
nanoparticles, which provide a large surface area to facilitate the removal of sulfonamides. More importantly, BiFeO
/MXene composites demonstrated remarkable sulfonamide adsorption capabilities compared to pristine MXene, which is due to the synergistic effect between BiFeO
and MXene. The kinetics and isotherm models of sulfonamide adsorption on BiFeO
/MXene are consistent with a pseudo-second-order kinetics and Langmuir model. BiFeO
/MXene had appreciable reusability after five adsorption-desorption cycles. Furthermore, BiFeO
/MXene is stable and retains its original properties upon desorption. The present work provides an effective method for eliminating sulfonamides from water by exploiting the excellent texture properties of BiFeO
/MXene.
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