Highlights
The role of electron transport characteristics in electromagnetic (EM) attenuation can be generalized to other EM functional materials.
The integrated functions of efficient EM absorption ...and green shielding open the view of EM multifunctional materials.
A novel sensing mechanism based on intrinsic EM attenuation performance and EM resonance coupling effect is revealed.
It is extremely unattainable for a material to simultaneously obtain efficient electromagnetic (EM) absorption and green shielding performance, which has not been reported due to the competition between conduction loss and reflection. Herein, by tailoring the internal structure through nano-micro engineering, a NiCo
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nanofiber with integrated EM absorbing and green shielding as well as strain sensing functions is obtained. With the improvement of charge transport capability of the nanofiber, the performance can be converted from EM absorption to shielding, or even coexist. Particularly, as the conductivity rising, the reflection loss declines from − 52.72 to − 10.5 dB, while the EM interference shielding effectiveness increases to 13.4 dB, suggesting the coexistence of the two EM functions. Furthermore, based on the high EM absorption, a strain sensor is designed through the resonance coupling of the patterned NiCo
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structure. These strategies for tuning EM performance and constructing devices can be extended to other EM functional materials to promote the development of electromagnetic driven devices.
Graphic Abstract
STAT3 is both a transcription activator and an oncogene that is tightly regulated under normal physiological conditions. However, abundant evidence indicates that STAT3 is persistently activated in ...several cancers, with a crucial position in tumor onset and progression. In addition to its traditional role in cancer cell proliferation, invasion, and migration, STAT3 also promotes cancer through altering gene expression via epigenetic modification, inducing epithelial-mesenchymal transition (EMT) phenotypes in cancer cells, regulating the tumor microenvironment, and promoting cancer stem cells (CSCs) self-renewal and differentiation. STAT3 is regulated not only by the canonical cytokines and growth factors, but also by the G-protein-coupled receptors, cadherin engagement, Toll-like receptors (TLRs), and microRNA (miRNA). Despite the presence of diverse regulators and pivotal biological functions in cancer, no effective therapeutic inventions are available for inhibiting STAT3 and acquiring potent antitumor effects in the clinic. An improved understanding of the complex roles of STAT3 in cancer is required to achieve optimal therapeutic effects.
Smart devices, nowadays, are inspiring the infinite vitality and possibilities of intelligent life, such as self‐power electromagnetic (EM) nanogenerator and microsensor, smart window, ...thermally‐driven EM absorber, interstellar energy deliverer, and so on. Herein, the latest and most impressive works of 3D nano–micro architectures and their smart EM devices are highly focused on. The most key information, including assembly strategy and mechanism, EM response, and approach‐structure‐function relationship, is extracted and well‐organized with profundity and easy‐to‐understand approach. The merit and demerit are revealed by comparison. What’s more, the brightest and most cutting‐edge smart EM devices constructed by 3D nano–micro architectures are reported as highlights, and the device principles are deeply dissected. Finally, a profound and top comment on the fast‐growing field as well as challenges are proposed, and the future directions are predicted intelligently.
3D nano–micro architectures and smart devices are “breaking new ground” to open a new chapter of the world—an intelligent world. New science and new technologies, new products, new industries, and new patterns, etc., are ever‐spawning, pushing new‐era scientific and technological revolution and industrial transformation. This is a great challenge, but even, a rare opportunity nowadays and in the future.
The integration of Internet of Things (IoT) and edge computing is currently a new research hotspot. However, the lack of trust between IoT edge devices has hindered the universal acceptance of IoT ...edge computing as outsourced computing services. In order to increase the adoption of IoT edge computing applications, first, IoT edge computing architecture should establish efficient trust calculation mechanism to alleviate the concerns of numerous users. In this paper, a reliable and lightweight trust mechanism is originally proposed for IoT edge devices based on multi-source feedback information fusion. First, due to the multi-source feedback mechanism is used for global trust calculation, our trust calculation mechanism is more reliable against bad-mouthing attacks caused by malicious feedback providers. Then, we adopt lightweight trust evaluating mechanism for cooperations of IoT edge devices, which is suitable for large-scale IoT edge computing because it facilitates low-overhead trust computing algorithms. At the same time, we adopt a feedback information fusion algorithm based on objective information entropy theory, which can overcome the limitations of traditional trust schemes, whereby the trust factors are weighted manually or subjectively. And the experimental results show that the proposed trust calculation scheme significantly outperforms existing approaches in both computational efficiency and reliability.
Ghrelin, a 28-aminoacid peptide, was isolated from the human and rat stomach and identified in 1999 as an endogenous ligand for the growth hormone secretagogue-receptor (GHS-R). In addition to ...stimulating appetite and regulating energy balance, ghrelin and its receptor GHS-R1a have a direct effect on the cardiovascular system. In recent years, it has been shown that ghrelin exerts cardioprotective effects, including the modulation of sympathetic activity and hypertension, enhancement of the vascular activity and angiogenesis, inhibition of arrhythmias, reduction in heart failure and inhibition of cardiac remodeling after myocardial infarction (MI). The cardiovascular protective effect of ghrelin may be associated with anti-inflammation, anti-apoptosis, inhibited sympathetic nerve activation, regulated autophagy, and endothelial dysfunction. However, the molecular mechanisms underlying the effects of ghrelin on the cardiovascular system have not been fully elucidated, and no specific therapeutic agent has been established. It is important to further explore the pharmacological potential of ghrelin pathway modulation for the treatment of cardiovascular diseases.
ObjectiveA comprehensive immune landscape for HBV infection is pivotal to achieve HBV cure.DesignWe performed single-cell RNA sequencing of 2 43 000 cells from 46 paired liver and blood samples of 23 ...individuals, including six immune tolerant, 5 immune active (IA), 3 acute recovery (AR), 3 chronic resolved and 6 HBV-free healthy controls (HCs). Flow cytometry and histological assays were applied in a second HBV cohort for validation.ResultsBoth IA and AR were characterised by high levels of intrahepatic exhausted CD8+ T (Tex) cells. In IA, Tex cells were mainly derived from liver-resident GZMK+ effector memory T cells and self-expansion. By contrast, peripheral CX3CR1+ effector T cells and GZMK+ effector memory T cells were the main source of Tex cells in AR. In IA but not AR, significant cell–cell interactions were observed between Tex cells and regulatory CD4+ T cells, as well as between Tex and FCGR3A+ macrophages. Such interactions were potentially mediated through human leukocyte antigen class I molecules together with their receptors CANX and LILRBs, respectively, contributing to the dysfunction of antiviral immune responses. By contrast, CX3CR1+GNLY+ central memory CD8+ T cells were concurrently expanded in both liver and blood of AR, providing a potential surrogate marker for viral resolution. In clinic, intrahepatic Tex cells were positively correlated with serum alanine aminotransferase levels and histological grading scores.ConclusionOur study dissects the coordinated immune responses for different HBV infection phases and provides a rich resource for fully understanding immunopathogenesis and developing effective therapeutic strategies.
Geodetic observations and seismic inversions suggest that the 2021 Mw7.4 Maduo earthquake's rupture velocity differs in two directions. However, the dynamic mechanisms underlying these differences ...remain unclear. To address this issue, we constructed a three-dimensional finite element model implementing heterogeneous fault geometry and real topography and simulated the Maduo earthquake's dynamic rupture process, with the tectonic stress field varying with depth. The results show that the uneven distribution of normal and shear stresses on the fault plane, due to the complex geometry of the seismogenic fault, is the primary factor controlling rupture velocity and slips on the fault plane of the Maduo earthquake. The modelled results reproduced basic kinematic characteristics as indicated by the observation and inversion results of the Maduo earthquake. Our study also suggests that if an earthquake occurs in a region without significant changes in velocity structure and stress field distribution, the complex geometry of the seismogenic fault is responsible for the dynamic rupture process. These findings provide important insights into the rupture behaviour of geometrically complex faults and have important implications for seismic hazard assessments of these complicated fault systems.
•The dynamics rupture process of the 2021 Maduo earthquake was modelled.•The modelled results reproduced the rupture process indicated by the geodetic observations and seismic inversions.•Stress heterogeneity due to the complex fault geometry is responsible for the asymmetric and uneven rupture process.
Highlights
The industrial application and foundational research of MXenes at gigahertz frequency are systematically reviewed.
The design principles of “lightweight, wide, and strong” are specifically ...highlighted.
Current challenges and future directions for MXenes in wireless communication and electromagnetic attenuation are outlined.
There is an urgent global need for wireless communication utilizing materials that can provide simultaneous flexibility and high conductivity. Avoiding the harmful effects of electromagnetic (EM) radiation from wireless communication is a persistent research hot spot. Two-dimensional (2D) materials are the preferred choice as wireless communication and EM attenuation materials as they are lightweight with high aspect ratios and possess distinguished electronic properties. MXenes, as a novel family of 2D materials, have shown excellent properties in various fields, owing to their excellent electrical conductivity, mechanical stability, high flexibility, and ease of processability. To date, research on the utility of MXenes for wireless communication has been actively pursued. Moreover, MXenes have become the leading materials for EM attenuation. Herein, we systematically review the recent advances in MXene-based materials with different structural designs for wireless communication, electromagnetic interference (EMI) shielding, and EM wave absorption. The relationship governing the structural design and the effectiveness for wireless communication, EMI shielding, and EM wave absorption is clearly revealed. Furthermore, our review mainly focuses on future challenges and guidelines for designing MXene-based materials for industrial application and foundational research.
Abstract In order to obtain an understanding of the relationship between the optical absorption and the transverse relaxation, the influences of linearly polarized light respectively at 133 Cs D1 and ...D2 lines on the transverse relaxation of ground-state 133 Cs atoms are studied. Under different vapor temperatures, light intensities and light frequencies, transverse spin relaxation times are separately measured for 133 Cs atoms in different hyperfine levels. For theoretically analyzing the measuring results, especially for an unusual trend that the transverse spin relaxation time rises with the increase of light intensity, photon absorption cross-sections of linearly polarized light by 133 Cs atoms are simulated. The experimental results show that through influencing the optical absorption and spin-exchange collisions, the linearly polarized light plays a remarkable role in the transverse spin relaxation. The results obtained by this paper can provide a guide to find the optimal intensity and frequency of linearly polarized light in practical applications for decreasing the influences of linearly polarized light on the transverse relaxation.
The transformation and upgrading of China's manufacturing industry is supported by smart and green manufacturing, which have great potential to empower the nation's green development. This study ...examines the impact of the Made in China 2025 industrial policy on urban green economic growth. This study applies the super-slacks-based measure model to measure cities' green economic growth, using the double machine learning model, which overcomes the limitations of the linear setting of traditional causal inference models and maintains estimation accuracy under high-dimensional control variables, to conduct an empirical analysis based on panel data of 281 Chinese cities from 2006 to 2021. The results reveal that the Made in China 2025 strategy significantly drives urban green economic growth, and this finding holds after a series of robustness tests. A mechanism analysis indicates that the Made in China 2025 strategy promotes green economic growth through green technology progress, optimizing energy consumption structure, upgrading industrial structure, and strengthening environmental supervision. In addition, the policy has a stronger driving effect for cities with high manufacturing concentration, industrial intelligence, and digital finance development. This study provides valuable theoretical insights and policy implications for government planning to promote high-quality development through industrial policy.
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