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  • GlycA, a novel biomarker of... GlycA, a novel biomarker of systemic inflammation and cardiovascular disease risk
    Connelly, Margery A; Otvos, James D; Shalaurova, Irina ... Journal of translational medicine, 10/2017, Volume: 15, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    GlycA is a novel spectroscopic marker of systemic inflammation with low intra-individual variability and other attributes favoring its clinical use in patients with chronic inflammatory and ...
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  • TPX2 is a novel prognostic ... TPX2 is a novel prognostic marker for the growth and metastasis of colon cancer
    Wei, Ping; Zhang, Nu; Xu, Ye ... Journal of translational medicine, 12/2013, Volume: 11, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    We have previously demonstrated an aberrant overexpression of the microtubule-associated protein TPX2 in colon cancer using a genome-wide gene expression profiling analysis. Here, we aim to ...
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  • PFN2, a novel marker of unf... PFN2, a novel marker of unfavorable prognosis, is a potential therapeutic target involved in esophageal squamous cell carcinoma
    Cui, Xiao-Bin; Zhang, Shu-Mao; Xu, Yue-Xun ... Journal of translational medicine, 05/2016, Volume: 14, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Esophageal squamous cell carcinoma (ESCC) is one of the most aggressively malignant tumors with dismal prognosis. Profilin 2 (PFN2) is an actin-binding protein that regulates the dynamics of actin ...
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  • Simvastatin prevents alveol... Simvastatin prevents alveolar bone loss in an experimental rat model of periodontitis after ovariectomy
    Xu, Xin-chen; Chen, Hui; Zhang, Xi ... Journal of translational medicine, 10/2014, Volume: 12, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Periodontitis is an inflammatory disease characterized by the loss of connective tissue and alveolar bone. There is an increasing evidence that periodontitis is associated with a number of chronic ...
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  • Early decline in serum phos... Early decline in serum phospho-CSE1L levels in vemurafenib/sunitinib-treated melanoma and sorafenib/lapatinib-treated colorectal tumor xenografts
    Lee, Woan-Ruoh; Shen, Shing-Chuan; Shih, Yi-Hsien ... Journal of translational medicine, 2015-Jun-13, 2015-6-13, 20150613, Volume: 13, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    Although targeted therapies have improved the clinical outcomes of cancer treatment, tumors resistance to targeted drug are often detected too late and cause mortality. CSE1L is secreted from tumor ...
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  • Vemurafenib resistance repr... Vemurafenib resistance reprograms melanoma cells towards glutamine dependence
    Hernandez-Davies, Jenny E; Tran, Thai Q; Reid, Michael A ... Journal of translational medicine, 07/2015, Volume: 13, Issue: 1
    Journal Article
    Peer reviewed
    Open access

    (V600) BRAF mutations drive approximately 50% of metastatic melanoma which can be therapeutically targeted by BRAF inhibitors (BRAFi) and, based on resistance mechanisms, the combination of BRAF and ...
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