Bajam se kao i drugi orašasti plodovi smatra izuzetno zdravom hranom. Stoga su u ekološkim uvjetima Ravnih kotara provedena istraživanja prisustva ostataka pesticida i mikotoksina u jezgrama bajama ...sorti Ferragnes, Ferraduela i sjemenjaku bajama. Istraživanja su provedena u 2022. godini, pri čemu su se koristile najosjetljivije metode analize. Korištenjem GC/MS/MS i LC/MS/MS analize na rezidue 402 pesticida, nije utvrđena prisutnost ni jednog pesticida ni u jednom uzorku. Glede mikotoksina, istraženi su ukupni aflatoksini i najopasniji aflatoksin AfB1 i ni u jednom uzorku nisu detektirani. Uz sve nutritivne, intrinzične i ine prednosti ovo je velika dodana vrijednost, budući su mikotoksini utvrđeni u najproizvodnijim zemljama i brojnim trgovinama diljem svijeta. Dobiveni rezultati nam potvrđuju da se bajami bez opterećenja pesticidima i mikotoksinima mogu kategorizirati kao funkcionalna hrana, odnosno koristiti ih više, jer pojačavaju imunitet i preveniraju brojne bolesti kod ljudi. Istraživanja pridonose boljoj valorizaciji bajama proizvedenih u ekološkim uvjetima Ravnih kotara, cjenovnoj stimulaciji za proizvođače i zdravstvenoj dobrobiti za konzumente.
Similary to other nuts, almond is considered to be extremely healthy. In this context, the research was conducted in the ecological conditions of the Ravni Kotari region on the presence of pesticide residues and mycotoxins in the seeds of the Ferragnes and Ferraduela almond varieties, as well as in the almond seedling. The study was done in 2022 and it used the most sensitive analytical methods. Following the GC/MS/MS and LC/MS/MS analysis for 402 pesticide residues, the results showed that no pesticide was detected in any of the samples. As far as mycotoxins are concerned, the analysis was carried out for total aflatoxins and the most dangerous aflatoxin AfB1, none of which were ultimately detected in any sample. In addition to all the nutritional, intrinsic and other advantages, this represents a great added value, since mycotoxins have been found in the most productive countries and in numerous stores around the world. The obtained results confirm that almonds can be categorized as functional food in the absence of pesticides and mycotoxins, i.e., the increased intake should be encouraged, since they strengthen immunity and prevent numerous diseases in humans. The research helps create better valorisation of almonds produced in the ecological conditions of Ravni Kotari region, at the same time benefiting manufacturers through price stimulation and consumers through the suggested health benefits.
Prije sedam godina (2016. godine) u Republici Hrvatskoj uvedeno je obavezno testiranje uređaja i strojeva za aplikaciju pesticida. Ispitivanje tehničke ispravnosti uređaja i strojeva provodi se svake ...3 godine u ovlaštenim ispitnim stanicama. Prema dosadašnjim podacima stanje tehničke ispravnosti uređaja i strojeva u RH prije sedam godina bilo je nezadovoljavajuće (loše). Međutim 2022. godine utvrđeno je da je prilikom testiranja bilo preko 88% ispravnih strojeva, bez obzira što je prosječna starost strojeva preko 21 godinu. U radu su putem Fitosanitarnog informacijskog sustava i analizom rezultata testiranja prikazani podaci o broju orošivača, prosječnoj starosti, proizvođaču, tipu stroja i najčešćim kvarovima.
Seven years ago (in 2016), compulsory testing of machines for pesticide application was introduced in the Republic of Croatia. Testing of the technical correctness of machines is carried out every 3 years in authorized testing stations. According to the data so far, the technical condition of machines in the Republic of Croatia seven years ago was unsatisfactory. However, in 2022, it was determined that during the testing, over 88% of the machines were technical in order, regardless of the fact that the average age of the machines is over 21 years. In the paper, data on the number of mist-blowers, average age, manufacturer, type of machine and the most common malfunctions is obtained through the Phytosanitary Information System and the analysis of test results.
Every year, about 300,000 people die because of pesticide poisoning worldwide. The most common pesticide agents are organophosphates and phosphides, aluminium phosphide (AlP) in particular. AlP is ...known as a suicide poison that can easily be bought and has no effective antidote. Its toxicity results from the release of phosphine gas as the tablet gets into contact with moisture. Phosphine gas primarily affects the heart, lungs, gastrointestinal tract, and kidneys. Poisoning signs and symptoms include nausea, vomiting, restlessness, abdominal pain, palpitation, refractory shock, cardiac arrhythmias, pulmonary oedema, dyspnoea, cyanosis, and sensory alterations. Diagnosis is based on clinical suspicion, positive silver nitrate paper test to phosphine, and gastric aspirate and viscera biochemistry. Treatment includes early gastric lavage with potassium permanganate or a combination with coconut oil and sodium bicarbonate, administration of charcoal, and palliative care. Specific therapy includes intravenous magnesium sulphate and oral coconut oil. Moreover, acidosis can be treated with early intravenous administration of sodium bicarbonate, cardiogenic shock with fluid, vasopresor, and refractory cardiogenic shock with intra-aortic baloon pump or digoxin. Trimetazidine may also have a useful role in the treatment, because it can stop ventricular ectopic beats and bigeminy and preserve oxidative metabolism. This article reviews the epidemiological, toxicological, and clinical/pathological aspects of AlP poisoning and its management.
Sekundarni metaboliti biljaka imaju važnu ulogu u reakciji biljaka na abiotički i biotički stres. Neke od bioaktivnih komponenti imaju izražena insekticidna svojstva, pa onda govorimo o insekticidnim ...biljkama poput dalmatinskog (Tanacetum cinerariifolium /Trevir./ Sch. Bip.) i kavkaškog buhača (Tanacetum coccineum (Willd.) Grierson) (aktivne komponente - piretrini), duhana (nikotin), neema (azadirahtin) i dr. Botanički insekticidi su uglavnom kraće perzistentnosti, pa su na osnovi njihove kemijske strukture razvijeni stabilniji sintetski insekticidi – piretroidi i neonikotinoidi, S ograničavanjem primjene kemijskih insekticida, botanički insekticidi dobivaju sve značajniju ulogu i u konvencionalnoj zaštiti bilja, ne samo ekološkoj. Posebno su značajni prirodni piretrini. Zbog brze razgradnje imaju kratku karencu što je često nedostatak, ali je i prikladno za zaštitu bilja prije same berbe, što je posebno prikladno kod suzbijanja octene mušice ploda.
Plants’ secondary metabolites have an important role in the plant’s response to abiotic and biotic stress. Some of the bioactive components have pronounced insecticidal properties, so they are called insecticidal plants such as Dalmatian (Tanacetum cinerariifolium /Trevir./ Sch. Bip.) and Caucasian pyrethrum (Tanacetum coccineum (Willd.) Grierson) (active components - pyrethrins), tobacco (nicotine), neem (azadirachtin), etc. Botanical insecticides are generally having shorter persistence. Based on their chemical structures, more stable synthetic insecticides have been developed – pyrethroids and neonicotinoids. With the restrictions in use of chemical insecticides, botanical insecticides are gaining an increasingly significant role in conventional plant protection, not only ecological. Natural pyrethrins are especially important. Due to their quick decomposition, they have a short withdrawal period, which is often a shortcoming, but it is also suitable for protecting plants before harvesting, which is especially suitable for spotted wing drosophila’s control.
Fipronil je insekticid širokog spektra djelovanja koji se ubraja u skupinu fenilpirazola. Prvi je insekticid koji je djelovao ciljajući GABA (gama-aminomaslačnu kiselinu) receptor i imao povoljnu ...selektivnu toksičnost prema insektima, ali ne i sisavcima. U skladu s uredbom (EZ) br. 1107/2009. fipronil nije odobren u sredstvima za zaštitu bilja te je zabranjeno tretiranje životinja namijenjenih za prehranu ljudi u Europskoj uniji (EU). Najveća dopuštena količina (NDK) fipronila ustvrđena je prema Uredbi 396/2005. o maksimalnim razinama ostataka pesticida u i na hrani i hrani za životinje biljnog i životinjskog podrijetla te za jaja i meso peradi iznosi 0,005 mg/kg. Svjetska zdravstvena organizacija (WHO) klasificirala je fipronil kao umjereno opasan pesticid II klase. Konzumiranje malih količina fipronila izaziva mučninu, glavobolju, povraćanje, bol u želucu, slabost i vrtoglavicu. Nakon apsorpcije u ljudi distribuira se u tkiva i oslobađa aktivne metabolite koji se nakupljaju uglavnom u masnom tkivu. Eksperimenti na miševima pokazali su da produljena izloženost visokim dozama fipronila prouzroči rak štitnjače u mužjaka i ženki. Pojava fipronila u jajima u EU zabilježena je 2016. godine u Belgiji. Kao posljedica ustvrđene zlouporabe fipronila na farmama pilića, države članice EU i Europska komisija dogovorile su provedbu ad-hoc monitoringa na ostatke insekticida fipronila i drugih akaricida u jajima i mesu peradi. Europska agencija za sigurnost hrane (EFSA) objavila je izvješće o rezultatima monitoringa te su u ukupnoj količini od 5439 uzoraka jaja i mesa peradi u zemljama članicama EU i Islandu u 742 uzorka (13,6 %) ustvrđene količine veće od zakonski dopuštenih. Većina nesukladnih rezultata odnosila se na fipronil u uzorcima kokošjih jaja i masnog tkiva kokoši nesilica. U uzorcima iz Republike Hrvatske nisu ustvrđeni nesukladni rezultati. Uzorci koji su prekoračili zakonsko ograničenje bili su podrijetlom iz Nizozemske, Italije, Njemačke, Poljske, Mađarske, Francuske, Slovenije i Grčke. Članice EU su u kontroli proizvoda koji se upućuju na tržište EU nesukladne rezultate fipronila prijavljivale u razdoblju 2017.-2019. putem centralnog sustava brzog uzbunjivanja za hranu i hranu za životinje - RASFF. Ukupno je prijavljeno 128 različitih proizvoda s nesukladnim koncentracijama fipronila, a najviše se obavijesti odnosilo na jaja i proizvode od jaja. Pri tome je u okviru poduzetih mjera za čak 45 prijava provedeno povlačenje kontaminiranih jaja s tržišta, obavljeno je po 9 zapljena i 9 službenih pritvora. Na temelju ustvrđenih nesukladnih nalaza fipronila Europska komisija je prema Provedbenoj Uredbi Komisije (EU) 2019/533 uvrstila njegovu kontrolu u okviru koordiniranog višegodišnjeg programa kontrole EU za razdoblje 2020.-2022.
Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole group. It is an insecticide that acts by targeting the GABA (gamma aminobutyric acid) receptor and has favourable selective toxicity to insects rather than mammals. Pursuant to Regulation (EC) No. 1107/2009, fipronil is not authorized in plant protection products and it is forbidden to treat animals intended for human consumption in the European Union (EU). The maximum permitted residue level (MRL) of fipronil is 0.005 mg/ kg for eggs and poultry, as established under Regulation 396/2005 on maximum levels of pesticide residues in and on food and feed of plant and animal origin. The World Health Organization (WHO) has classified fipronil as a mildly dangerous class II pesticide. Consuming small amounts of fipronil causes nausea, headache, vomiting, stomach pain, weakness and dizziness. After absorption in humans, it is distributed into tissues and releases active metabolites that accumulate mainly in adipose tissue. Experiments in mice have shown that prolonged exposure to high doses of fipronil causes thyroid cancer in males and females. The occurrence of fipronil in eggs in the EU was reported in Belgium in 2016. As a consequence of the identified misuse of fipronil found on chicken farms, EU Member States and the European Commission have agreed to carry out ad-hoc monitoring of fipronil insecticides and other acaricides in eggs and poultry meat. In a monitoring report published by the European Food Safety Authority (EFSA), 742 samples (13.6%) of a total of 5439 eggs and poultry samples in EU Member States and Iceland exceeded the legal limits. Most inconsistent results were related to fipronil in chicken eggs and fat of laying hens. No non-compliant results were found in samples from the Republic of Croatia. Samples exceeding the legal limit originated from the Netherlands, Italy, Germany, Poland, Hungary, France, Slovenia and Greece. EU Member States reported non-compliant fipronil results in the control of products marketed in the EU during 2017-2019 via the Central Rapid Alert System for Food and Feed (RASFF). In total, 128 different products with non-compliant fipronil concentrations were reported, with the most reports regarding eggs and egg products. In the framework of the measures taken, as many as 45 complaints were filed to withdraw contaminated eggs from the market, and nine confiscations and nine official detentions were carried out. Based on the identified non-compliant findings of fipronil, the European Commission has listed its control under Commission Coordinated Implementing Regulation (EU) 2019/533 under the coordinated multi-annual EU control program for the period 2020-2022.
Porast slučajeva muške neplodnosti tijekom posljednja dva desetljeća, vjerojatno i zbog izloženosti okolišnim čimbenicima, izazvao je značajan interes. Izvješća klinika za neplodnost pokazala su da ...kronične bolesti i nasljedni čimbenici ili neke zdravstvene smetnje mogu samo djelomično objasniti trenutačnu incidenciju muške neplodnosti. Životni okoliš i radna okolina mogu imati značajnu ulogu u izlaganju složenim smjesama spojeva s endokrinim djelovanjem (ED), koji su povezani s raznim poremećajima plodnosti. Cilj je ovoga preglednog rada dati uvid u trenutačno znanje o tipovima izloženosti koji mogu biti povezani s muškom neplodnošću. Naše se istraživanje oslanjalo na sustavnu pretragu PubMeda, Scopusa i Web of Sciencea za članke objavljene od siječnja 2000. do rujna 2020. Rezultati su pokazali da je za neke čimbenike dobro dokumentirana povezanost s muškom neplodnošću, što uključuje pušenje, neke fiziološke poremećaje te kronične bolesti poput pretilosti i dijabetesa, koji sami po sebi mogu odražavati životne navike i izloženost okolišu, posebice spojevima s ED-om poput ftalata, bisfenola, pesticida i protupožarnih zaštita. Međutim, broj studija o etiologiji muške neplodnosti još je uvijek premalen u usporedbi s veličinom zahvaćene populacije. Medicina rada tijekom sistematskih pregleda ne prikuplja podatke o muškoj neplodnosti premda su spojevi s ED-om prisutni u mnogim tehnološkim procesima.
The upsurge in male infertility over the last two decades, possibly due to environmental exposure, has raised significant interest, particularly boosted by reports from fertility clinics, which ...showed that chronic diseases and hereditary or other medical conditions might only partially explain current incidence of male infertility. Both environmental and occupational settings may have a significant role in exposure to complex mixtures of endocrine disruptors (ED), which play a major role in fertility disorders. The aim of this review is to give an insight into the current knowledge on exposure settings which may be associated with male infertility. Our study relied on a systematic search of PubMed, Scopus, and Web of Science for articles published between January 2000 and September 2020. It showed that some well documented factors associated with male infertility include smoking, and physiological disturbances or chronic diseases such as obesity and diabetes, which in turn, may also reflect lifestyle choices and environmental exposures, especially to EDs such as phthalates, bisphenols, pesticides, and flame retardants. However, the number of studies on the aetiology of male infertility is still too low in comparison with the size of affected population. Occupational health follow-ups and medical surveillance do not collect any data on male infertility, even though ED chemicals are part of many technological processes.
Contaminants of Medicinal Herbs and Herbal Products Kosalec, Ivan (Faculty of Pharmacy and Biochemistry, University of Zagreb, Zagreb, Croatia); Cvek, Josipa (Agency for Medicinal Products and Medical Devices, Zagreb, Croatia); Tomić, Siniša (Agency for Medicinal Products and Medical Devices, Zagreb, Croatia)
Arhiv za higijenu rada i toksikologiju,
12/2009, Volume:
60, Issue:
4
Journal Article
Peer reviewed
Open access
Medicinal plants have a long history of use in therapy throughout the world and still make an important part of traditional medicine. Thus, medicinal plants and herbal products must be safe for the ...patient (consumer). This review addresses biological contaminants (microbes and other organisms) and chemical contaminants (mycotoxins, toxic elements such as heavy metals, and pesticide residues) as major common contaminants of medicinal herbs and herbal products. To prevent and screen for contamination and ensure safety and conformity to quality standards, medicinal herbs and herbal products should be included in appropriate regulatory framework.
Ljekovito bilje i biljni proizvodi već tisućljećima nalaze široku primjenu u razli _itim sustavima tradicionalnog lije _enja. Stoga je njihova neškodljivost, ponajprije uvjetovana kakvoćom biljne sirovine, od izuzetne važnosti za javno zdravstvo. Od mogućih _imbenika koji utje _u na kakvoću ljekovitog bilja i biljnih proizvoda ovaj pregledni rad osvrće se na naj _ešće prisutna biološka (mikroorganizmi) i kemijska one _išćenja (mikotoksini, toksi _ni elementi poput teških metala te ostaci pesticida). S ciljem postizanja ujedna _enih standarda kakvoće te osiguranja sigurnosti primjene biljnih proizvoda od vitalne su važnosti zakonski propisi koji moraju u odgovarajućim regulatornim okvirima obuhvatiti ovu skupinu proizvoda s naglaskom na sprje _avanju i ispitivanju njihovih mogućih one _išćenja.
Alta Valle del Tevere, in Central Italy, is one of the European areas where tobacco farming is most developed. But Alta Valle del Tevere is also one of the areas where the incidence and the death ...rate of stomach cancer are higher than the regional and national average rate. According to many local citizens, this double feature intersects in the supposed dangerousness of the chemical products used for tobacco farming. This article focuses on the genealogy, the political management and the effects of this “rumour”. Taking into consideration local business, political and healthcare management, this paper analyses the elements determining the moral economy of the “tolerance threshold” about the supposed link between tobacco farming and oncological incidence.
Neupitna je iznimno važna uloga koju pčele imaju u prirodi kao oprašivači biljaka i proizvođači određenih nezamjenjivih prirodnih proizvoda. No, u posljednje vrijeme sve se češće pčele spominju kao ...žrtve onečišćenja okoliša koje predstavlja stvarnu prijetnju njihovom opstanku. Pčele su opnokrilasti kukci koji broje oko 20 000 poznatih vrsta, a nama najpoznatija i najbliža je medonosna pčela, odnosno siva kranjska pčela (Apis mellifera carnica). Pčele su zaslužne za 87,5 % oprašivanja kod biljaka cvjetnjača, što je posebno važno u poljoprivrednoj proizvodnji, dok se direktna korist od medonosnih pčela očituje i u pčelinjim proizvodima kao što su: med, vosak, propolis, pelud, otrov, matična mliječ. Stoga je ključno otkriti i pratiti na koji način i u kojoj mjeri onečišćivala poput teških metala i pesticida, iz vode, tla i zraka dospijevaju u biljke i njihove produkte kao i u same pčele. Sve se ono što pčele proizvode za sebe i ljudsku uporabu može odraziti na njihovo i na ljudsko zdravlje. Ovdje je potrebno sagledati cjelokupnu povezanost između, uvjetno rečeno, nežive prirode, tvari u vodi, tlu i zraku, s okolišnim uvjetima poput sve izraženije promjene staništa i klimatskih promjena te cjelokupni utjecaj na pčelinje populacije koje su se pokazale kao neprocjenjivi biopokazatelji u biomonitoringu onečišćenja okoliša.
The role of bees in nature as plant pollinators and producers of certain irreplaceable natural products is indisputably crucial. However, recently, bees are increasingly being referred to as victims of environmental contamination, which poses a real threat to their survival. Bees are insects of the order Hymenoptera, with around 20,000 known species. The most common in this region is the honey bee or grey honey bee (Apis mellifera carnica). Bees are responsible for 87.5% pollination of flowering plants, which is especially important in agricultural production, while direct benefits of honey bees are seen in bee products, such as honey, bees wax, propolis, pollen, bee poison, and royal jelly. It is crucial to identify how and to what extent contaminants, such as heavy metals and pesticides from water, soil and air, reach plants and their products, and the bees and their products, since this can affect both bee health and human health. The overall links between inanimate nature, such as substances in water, soil and air, with external conditions, such as changes in habitats and climate changes should be considered, and their impacts on bee populations determined, as they are invaluable bio-indicators for biomonitoring of environmental contamination.
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