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  • Endokrini tumorji trebušne slinavke - naša kazuistika in kirurški problemi = Endocrine tumours of the pancreas - own experience and surgical problems
    Repše, Stanislav
    Background. Due to small size, heterogeneous entities and sometimes unrealiable or even unsuccessfoul preoperative localisation endocrine pancreastumours (EPT) represent a serious surgical problem. ... Patients and methods. Retrospective analysis of our-own series of 31 EPT patients: 24 insulinomas, 3 carcinods, 2 gastrinoma, 1 glucagonoma and 1 somatostatinoma. Type of surgery performed: insulinoma enucleation 15-times, left pancreatectomy 10times, pancreatoduadenectomy twice, segmental (central) pancreas resection once, tumor resection without pancreas resection (gastrinoma and glukagonoma) twice, right hepatectomy (metastases of gastrinoma) once. In four patients with malignant insulinomas and a female patient with carcinoid liver metastases were resected simultaneously. Results.There was no case of postoperative death. In 3 patients with enucleation of insulinoma from the head of pancreas secretion with excessive amylase values persisted in the side of drainage for a longer time; but it stopped spontaneously. In 3 patients percutaneous drainage of intraabdominal collection was necessary. One female patient developped pulmonary embolism. In4 EIT patients recurency occurred one to 8 years after the first operation. All 4 patients underwent several operations and died due to tumour progression. There is no follow-up for 3 patients with malignant insulinoma with liver metastases (not Slovene residents). Conclusions: Accurate preoperative EPT localisation is the bases for successful surgery. Benign endocrine tumours should be enucleated; malignant ones require resection in the healthy tissue and removal of the metastases.
    Type of material - article, component part
    Publish date - 2001
    Language - slovenian
    COBISS.SI-ID - 13171161