Značajke upale pluća dobivene u domaćem okolišu koju prouzročuje Chlamydia pneumoniae kod hospitaliziranih bolesnika
Sočan, Maja
211 adult patients hospitalised in Department for Infectious Diseases in Ljubljana with community-acquired pneumonia were studied prospectively to determine the microbial etiology of pneumonia in ...period between April 1996 andMarch 1997. Blood culture was positive in 23 patients. Streptococcus pneumoniae was the most frequently isolated bacteria Chlamydia pneumoniae pneumonia was confirmed serologically in 18% patients. Antibodies confirming acute Mycoplasma pneumoniae, Legionella, Chlamydia psittaci and Coxiella burnetii infection were found in lower number of patients. Acute viral infection was confirmed in 51 (24.1%) patients, influenza A virus was most frequently identified. Viral infections were most often found during the winter and early spring. In the same period, the highest number of pneumonia patients were treated in the hospital. Two serological methods (complement fixation test and enzyme-immune assay) used for diagnosing viral infection, were compared. Specificity was found to be good, but sensitivity quite low. Different microbiological methods used for identification of C. pneumoniae infection were compared. The comparison of the microimmunofluorescence test and enyme-immune assay revealed low sensitivity and better specificity of the latter test. The was no correlation good between direct immunofluorescence test, proceded in a throat swab and microimmunofluorescence test. Polymerase chain reaction was proceeded only on throat specimens of patients with C. pneumoniae pneumonia. Less than half of the specimen were found to be positive. (Abstract truncated at 2000 characters).
Type of material - dissertation
Publication and manufacture - Zagreb : [M. Sočan], 2002
doktorske disertacije SOČAN Maja Značajke IN: 020031023
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