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Sparking signals [Elektronski vir] : kinases as molecular signatransducers and pharmacological drug targets in inflammation"Protein phosphorylation is an essential post-translational modification that modulates cell-cell communication. Substrate phosphorylation by protein kinases controls intracellular signal ... transduction pathways that mediate cell proliferation, migration, differentiation, and metabolism. The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. Inhibitors that target protein kinases have proven efficacious in clinical settings and their continued development is the current focus of many drug discovery groups."--JacketType of material - e-bookPublication and manufacture - Berlin ; New York : Springer, 2008Language - englishISBN - 978-3-540-73501-4; 3-540-73501-1; 978-3-540-73500-7; 3-540-73500-3COBISS.SI-ID - 1540640479
Link(s):
SpringerLink e-books 2008-2012Celotno besedilo dostopno za uporabnike SpringerLink slovenskega konzorcija neprofitnih institucij
Full text accessible to the users of SpringerLink Slovenian Consortium of Non-Profit Institutions
DOI
Other authors
Baier, Gottfried |
Ernst Schering Research Foundation
Collection
Ernst Schering Foundation symposium proceedings
Topics
Pharmacokinetics |
Congresses |
Protein kinases |
Congresses |
Drug targeting |
Congresses |
Cellular signal transduction |
Congresses |
Anti-inflammatory agents |
Pharmacokinetics |
Congresses |
Inflammation |
drug therapy |
Congresses |
Anti-Inflammatory Agents |
therapeutic use |
Congresses |
Protein Kinase Inhibitors |
therapeutic use |
Congresses |
Protein Kinases |
drug effects |
Congresses |
Medicine |
MEDICAL |
Pharmacology |
Biomédecine |
Sciences de la vie |
Anti-Inflammatory Agents |
therapeutic use |
Protein Kinase Inhibitors |
therapeutic use |
Protein Kinases |
drug effects |
Pharmacokinetics |
Protein kinases |
Drug targeting |
Cellular signal transduction |
Anti-Inflammatory Agents |
pharmacokinetics |
Electronic books |
Medicine |
Inflammation |
drug therapy |
Electronic books
Shelf entry
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