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Genetic analysis reveals multiple intergenic region and central variable region in the African swine fever virus variants circulating in Serbia [Elektronski vir]Glišić, Dimitrije ...This study provides the first comprehensive report on the molecular characteristics of African swine fever virus (ASFV) variants in Serbia between 2019 and 2022. Since its first observation in July ... 2019, the disease has been found in wild boar and domestic swine. The study involved the analysis of 95 ASFV-positive samples collected from 12 infected administrative districts in Serbia. Partial four genomic regions were genetically characterized, including B646L, E183L, B602L, and the intergenic region (IGR) between the I73R-I329L genes. The results of the study suggest that multiple ASFV strains belonging to genotype II are circulating in Serbia, as evidenced by the analysis of the IGR between I73R-I329L genes that showed the most differences. Furthermore, the phylogenetic analysis of the B602L gene showed three different clades within the CVR I group of ASFV strains. Regarding the IGR, 98.4% were grouped into IGR II, with only one positive sample grouped into the IGR III group. These findings provide essential insights into the molecular characteristics of ASFV variants in Serbia and contribute to the knowledge of circulating strains of ASFV in Europe. However, further research is necessary to gain a better understanding of ASFV spread and evolution.Source: Veterinary research communications [Elektronski vir]. - ISSN 1573-7446 (Vol. , 2023, str. 1-12)Type of material - e-article ; adult, seriousPublish date - 2023Language - englishCOBISS.SI-ID - 154238467
Author
Glišić, Dimitrije |
Milićević, Vesna, 1980- |
Krnjaić, Dejan |
Toplak, Ivan, 1972- |
Prodanović, Radiša |
Gallardo, Carmina |
Radojičić, Sonja
Topics
Viruses |
African Swine Fever |
Genotype |
DNA, Intergenic |
Swine
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Glišić, Dimitrije | ![]() |
Milićević, Vesna, 1980- | ![]() |
Krnjaić, Dejan | ![]() |
Toplak, Ivan, 1972- | 20040 |
Prodanović, Radiša | ![]() |
Gallardo, Carmina | ![]() |
Radojičić, Sonja | ![]() |
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and: SICRIS
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