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Mechanical properties and drug permeability of the PA6 membranes prepared by immersion precipitation from PA6 - formic acid - water systemAulova, Alexandra ...The paper presents the effect of polymer solution composition on the morphology, mechanical properties and drug permeability of the asymmetric polyamide 6 (PA6) membranes prepared by immersion ... precipitation. The effect of polymer solution composition on morphology, mechanical properties and permeability of the produced membrane is considered, since these properties are of relevance for drug delivery applications. PA6-formic acid-deionized water solutions were used to prepare membranes for further characterization with differential scanning calorimetry and scanning electron microscopy for morphology analysis, tensile testing and drug permeability tests. The results show that the amount of PA6 does not significantly affect morphology of the membrane, while having pronounced effect on tensile elastic modulus (50% increase). On the other hand, the concentration of formic acid in solution (dissolution intensity) influences crystallization dynamics and significantly changes the morphology of membrane (in the range of approximately 75-100 wt% of formic acid concentrations), consequently having effect on drug permeability.Source: Journal of membrane science. - ISSN 0376-7388 (Vol. 562, Sep. 2018, str. 67-75)Type of material - article, component part ; adult, seriousPublish date - 2018Language - englishCOBISS.SI-ID - 16094747
Author
Aulova, Alexandra |
Cvenkel, Anže |
Žakelj, Simon |
Planinšek, Odon |
Kristl, Albin |
Emri, Igor
Topics
polyamide 6 |
formic acid |
immersion precipitation |
tensile test |
drug permeability |
poliamid 6 |
mravljična kislina |
precipitacija pri potapljanju |
natezni preizkus |
prepustnost zdravil
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DRS, in which the journal is indexed
Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Aulova, Alexandra | 33907 |
Cvenkel, Anže | ![]() |
Žakelj, Simon | 22659 |
Planinšek, Odon | 14935 |
Kristl, Albin | 11122 |
Emri, Igor | 04316 |
Source: Personal bibliographies
and: SICRIS
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