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Low prevalence of active COVID-19 in Slovenia : a nationwide population study on a probability-based sampleMaver Vodičar, Polona ...Objectives Accurate population-level assessment of the COVID-19 burden is fundamental for navigating the path forward during the ongoing pandemic, but current knowledge is scant. We conducted the ... first nationwide population study using a probability-based sample to assess active SARS-CoV-2 infection, combined with a longitudinal follow-up of the entire cohort over the next 6 months. Baseline SARS-CoV-2 RNA testing results and the first 3-week follow-up results are presented. Methods A probability-based sample of the Slovenian population (N = 2.1 million) was selected from the Central Population Register (n = 3,000). SARS-CoV-2 RNA was detected in nasopharyngeal samples using the cobas 6800 SARS-CoV-2 assay. Each participant filled in a detailed baseline questionnaire with basic sociodemographic data and current and past medical history compatible with COVID-19. After 3 weeks participants were interviewed for the presence of COVID-19-compatible clinical symptoms and signs, including in household members, and offered immediate testing for SARS-CoV-2 RNA if indicated. Results 1,368 (46%) individuals consented to participate and completed the questionnaire. Two of 1,366 participants tested positive for SARS-CoV-2 RNA (prevalence 0.15%; posterior mean 0.18%, 95% Bayesian CI 0.03-0.47%; 95% HDR 0.01-0.41%). No newly diagnosed infections occurred in the cohort during the first 3-week follow-up round. Conclusions The low prevalence of active COVID-19 infections found in this study accurately predicted the dynamic of the epidemic in Slovenia over the subsequent month. Properly designed and timely executed studies using probability-based samples combined with routine target-testing figures provide reliable data for informed decisions on relaxing or strengthening mitigation strategies.Source: Clinical microbiology and infection : the official publication of the European society of clinical microbiology and infectious dieseases. - ISSN 1198-743X (Vol. 26, iss. 11, Nov. 2020, str. 1514-1519)Type of material - article, component part ; adult, seriousPublish date - 2020Language - englishCOBISS.SI-ID - 23262211
Author
Maver Vodičar, Polona |
Oštrbenk Valenčak, Anja |
Zupan, Blaž, računalništvo |
Avšič-Županc, Tatjana |
Kurdija, Slavko |
Korva, Miša |
Petrovec, Miroslav |
Demšar, Janez, računalništvo |
Knap, Nataša, 1978- |
Štrumbelj, Erik |
Vehovar, Vasja |
Poljak, Mario, 1965-
Topics
COVID-19 |
SARS-CoV-2 |
serology |
COVID-19 |
SARS-CoV-2 |
serologija
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source: Clinical microbiology and infection : the official publication of the European society of clinical microbiology and infectious dieseases. - ISSN 1198-743X (Vol. 26, iss. 11, Nov. 2020, str. 1514-1519)
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Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Maver Vodičar, Polona | 36669 |
Oštrbenk Valenčak, Anja | 35359 |
Zupan, Blaž, računalništvo | 12536 |
Avšič-Županc, Tatjana | 10331 |
Kurdija, Slavko | 12527 |
Korva, Miša | 30696 |
Petrovec, Miroslav | 15902 |
Demšar, Janez, računalništvo | 16324 |
Knap, Nataša, 1978- | 28601 |
Štrumbelj, Erik | 29486 |
Vehovar, Vasja | 10155 |
Poljak, Mario, 1965- | 11622 |
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