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Paptid uroaktivin, kot aktivator encima urokinaze : SI 22865 (A), 2010-03-31Obermajer, Nataša ; Doljak, Bojan ; Kos, Janko, 1959-In the course of intense studies that brought to the present invention, the inventors discovered, that the peptide uroaktivin with the amino acid sequenceSEQ ID NO: 1 binds to and increases the ... activity of urokinase type plasminogen activator (urokinase, uPA) and tissue type plasminogen activator (tPA). The present invention in the first place provides the amino acid sequence of the peptide uroaktivin - SEQ ID NO: 1. The present invention also provides the use of peptide uroaktivin for a more efficient therapy of diseases or conditions for which thrombolytic medicines are indicated. These conditions are especially the following: acute coronary thrombosis (acute myocardial infarction), acute ischemic brain infarction, acute lung thrombo embolism, deep venous thrombosis, acute arterial thromboembolism, acute arterial thrombosis. The peptide uroaktivin would as well be used for assurance of permeability of arteriovenous cannulas and intravenous catheters.Type of material - patent ; adult, seriousPublication and manufacture - Ljubljana : Urad RS za intelektualno lastnino, 2010Language - slovenianCOBISS.SI-ID - 2788721
Author
Obermajer, Nataša |
Doljak, Bojan |
Kos, Janko, 1959-
Other authors
Univerza v Ljubljani |
Fakulteta za farmacijo
Topics
patenti |
urokinaze |
peptid uroaktivin |
farmacija
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Database name | Field | Year |
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Obermajer, Nataša | 25494 |
Doljak, Bojan | 19785 |
Kos, Janko, 1959- | 04648 |
Source: Personal bibliographies
and: SICRIS
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