-
Treatment challenges and delivery systems in immunomodulation and probiotic therapies for periodontitis : an expert reviewZidar, Anže ...Introduction: Periodontitis is a widespread illness that arises due to disrupted interplay between the oral microbiota and the host immune response. In some cases, conventional therapies can provide ... temporary remission, although this is often followed by disease relapse. Recent studies of periodontitis pathology have promoted the development of new therapeutics to improve treatment options, together with local application using advanced drug delivery systems. Areas covered: This paper provides a critical review of the status of current treatment approaches to periodontitis, with a focus on promising immunomodulation and probiotic therapies. These are based on delivery of small molecules, peptides, proteins, DNA or RNA, and probiotics. The key findings on novel treatment strategies and formulation of advanced delivery systems, such as nanoparticles and nanofibers, are highlighted. Expert opinion: Multitarget therapy based on antimicrobial, immunomodulatory, and probiotic active ingredients incorporated into advanced delivery systems for application to the periodontal pocket can improve periodontitis treatment outcomes. Translation of such adjuvant therapy from laboratory to patient is expected in the future.Source: Expert opinion on drug delivery. - ISSN 1742-5247 (Vol. 18, iss. 9, 2021, str. 1229-1244)Type of material - article, component partPublish date - 2021Language - englishCOBISS.SI-ID - 57179139
Author
Zidar, Anže |
Kristl, Julijana |
Kocbek, Petra, farmacevtka |
Zupančič, Špela, farmacevtka
Topics
Dostavni sistemi |
Nanotehnologija |
Nanomateriali |
Parodontitis |
Zdravljenje |
Imunomodulacija |
Probiotiki |
nanovlakna |
periodontal disease |
periodontitis |
adjuvant therapy |
immunomodulation |
probiotics |
vaccination |
immunization |
nanotechnology |
nanofibers |
local drug delivery
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Shelf entry
Permalink
- URL:
Impact factor
Access to the JCR database is permitted only to users from Slovenia. Your current IP address is not on the list of IP addresses with access permission, and authentication with the relevant AAI accout is required.
Year | Impact factor | Edition | Category | Classification | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Select the library membership card:
DRS, in which the journal is indexed
Database name | Field | Year |
---|
Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
---|---|
Zidar, Anže | 53870 |
Kristl, Julijana | 09032 |
Kocbek, Petra, farmacevtka | 24402 |
Zupančič, Špela, farmacevtka | 36439 |
Select pickup location:
Material pickup by post
Notification
Subject headings in COBISS General List of Subject Headings
Select pickup location
Pickup location | Material status | Reservation |
---|
Please wait a moment.