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  • Proučevanje naravnih gostiteljev virusa klopnega meningoencefalitisa v aktivnih in latentnih žariščih klopnega meningoencefalitisa v Sloveniji = Examination of tick-borne encephalits virus natural reservoirs in active and latent tick-borne encephalitis foci in Slovenia
    Malovrh, Tomaž ; Marc-Malovrh, Mateja
    Tick-borne encephalitis is the most important human central nervous system virus infection in Europe. The virus is maintained in nature by a cycle involving reservoirs (small mammals, deer) and ... vector (ticks). Tick-borne encephalitis occurs in endemic areas, which vary in activity. The purpose of the study was to determine the species and frequency of tick-borne encephalitis infection among small mammales caught in Gornjanci and Tenetiše endemic areas. The enzyme immunoassay was used for demonstration of specific viral antibodies, and the polymerase chain reaction for direct detection of viral genome. Seroprevalence was 8,3%, while viral genome was detected in 45,9% of the tested animals. Our study confirmed that the demonstration of viral antibodies alone cannot provide an accurate information of the incidenceof tick-borne encephalitis infection in small mammals. The yellow-necked mouse was found to be a primary reservoir of tick-borne encephalitis virus in Slovenia. No differenc ein infection rate was found between studied natural foci. Polymerase chain reaction, which was for the first time employed for the detection of tick-borne encephalitis in natural reservoirs, represents a convenient tool for determining tick-borne encephalitis natural foci.
    Source: Medicinski razgledi : [medicinski pregledni, strokovni in raziskovalni članki]. - ISSN 0025-8121 (Letn. 36, št. 4, 1997, str. 465-478)
    Type of material - article, component part
    Publish date - 1997
    Language - slovenian
    COBISS.SI-ID - 7989465

    Link(s):

    Digitalna knjižnica Slovenije - dLib.si

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