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Multi-parameter risk assessment of forty-one selected substances with endocrine disruptive properties in surface waters worldwideGrobin, Andrej ; Roškar, Robert, 1975- ; Trontelj, JurijThe increasing use of substances with endocrine disruptive properties (EDs) not only impacts aquatic organisms but can also have a direct negative effect on human health. In this comprehensive ... worldwide review, we collected ecotoxicology and concentration data observed in surface water for 53 high-potency EDs and performed a risk assessment. The compounds were selected from the EU watchlist of priority substances, expanded with new compounds of emerging concern (total 41), where quantifiable data were available for the past three years (2018-2020). The risk quotients ranged from <0.01 for 22 substances to 1974 for tamoxifen. The frequency of samples in which the predicted no-effect concentrations were exceeded also varied, from 1.8% to 92.7%. By using the comprehensive multi-parameter risk assessment in our study, the most current to date, we determined that tamoxifen, imidacloprid, clothianidin, four bisphenols (BPA, BPF, BPS, and BPAF), PFOA, amoxicillin, and three steroid hormones (estriol, estrone, and cyproterone) pose significant risks in the environment. Comparing two structurally very similar bisphenols, BPA and BPB, suggested that the risk from BPB is currently underestimated by at least four orders of magnitude due to the lack of ecotoxicological data availability. The methodological limitations encountered suggest that a standardized methodology for data selection and assessment is necessary, highlighting the fact that some substances are currently under-represented in the field of ecotoxicological research. A new prioritization system is therefore presented, which provides a potential basis for new substances to be included in environmental monitoring lists.Source: Chemosphere. - ISSN 0045-6535 (Vol. 287, part 2, 2022, str. 1-14)Type of material - article, component partPublish date - 2022Language - englishCOBISS.SI-ID - 83326467
Author
Grobin, Andrej |
Roškar, Robert, 1975- |
Trontelj, Jurij
Topics
Endokrinologija |
Ekotoksikologija |
endocrine disruptors |
ecotoxicology |
multi-parameter risk assessment |
priority index |
surface water |
endokrine motilne lastnosti |
ekotoksikologija |
večparametrska ocena tveganja |
prednostni indeks |
površinska voda
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Author | Grobin, Andrej ; Roškar, Robert, 1975- ; Trontelj, Jurij |
Title | Multi-parameter risk assessment of forty-one selected substances with endocrine disruptive properties in surface waters worldwide |
Publication date | 2022-01-28 |
COBISS.SI-ID | 83326467 |
Publication version in repository | Publisher's version |
Publication licence | Creative Commons Attribution 4.0 International |
Embargo | Immediate publication for public |
Project(s) from which the publication was funded
Title | Acronym | Project ID | Funder |
---|---|---|---|
Farmacevtska tehnologija: od dostavnih sistemov učinkovin do terapijskih izidov zdravil pri otrocih in starostnikih | P1-0189-2018 |
Javna agencija za znanstvenoraziskovalno in inovacijsko dejavnost Republike Slovenije |
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Grobin, Andrej | 52093 |
Roškar, Robert, 1975- | 23549 |
Trontelj, Jurij | 23420 |
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