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Stabilnostna študija gastrorezistentnih pelet z laktoferinom [Elektronski vir] = Stability study of enteric-coated pellets containing lactoferrinOsel, Nika, farmacevtka ...Laktoferin (Lf) je multifunkcionalen glikoprotein, ki veže železo in ima številne ugodne učinke na zdravje ljudi, zato se zanimanje za izdelke z Lf povečuje. Namen raziskovalnega dela je bil ... ovrednotiti kakovost in stabilnost gastrorezistentnih pelet z Lf, ki smo jih pripravili v Wursterjevi komori z oblaganjem nevtralnih peletnih jeder z Lf in gastrorezistentno oblogo. Vsebnost Lf v formulaciji je bila 200 mg. S testi sproščanja smo ugotovili, da gastrorezistentna obloga zadostno zaščiti Lf, saj se je po dveh urah v kislem mediju sprostilo manj kot 10 % Lf. Rezultati stabilnostne študije pri dolgoročnih in pospešenih pogojih shranjevanja so pokazali, da gastrorezistentna obloga, želatinska kapsula in Alu-Alu ovojnina stabilizirajo Lf. Raziskava je pokazala, da imata izbira ustrezne ovojnine in pogojev shranjevanja pomembno vlogo pri zagotavljanju kakovosti in stabilnosti izdelka z Lf.Type of material - conference contribution ; adult, seriousPublish date - 2022Language - slovenian, englishCOBISS.SI-ID - 99174659
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DRS, in which the journal is indexed
Database name | Field | Year |
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Links to authors' personal bibliographies | Links to information on researchers in the SICRIS system |
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Osel, Nika, farmacevtka | 53673 |
Grilc, Blaž, farmacevt | 51457 |
Planinšek Parfant, Timeja | 52446 |
Kristl, Albin | 11122 |
Roškar, Robert, 1975- | 23549 |
Source: Personal bibliographies
and: SICRIS
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