Vascular aging: Molecular mechanisms and potential treatments for vascular rejuvenation

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Vascular aging: Molecular mechanisms and potential treatments for vascular rejuvenation

Mistriotis, Panagiotis; Andreadis, Stelios T

Ageing research reviews, 08/2017, Volume: 37

Journal Article

Highlights • Age-induced cell intrinsic and extrinsic changes alter EC and SMC function. • EC and SMC dysfunction mediates vascular aging. • Stem cell and gene therapies may restore the impaired vascular cell function and promote vascular repair. • Aging diminishes stem cell function. • NANOG reverses stem cell aging.

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Mistriotis, Panagiotis | Andreadis, Stelios T

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