Vasospasm and subsequent stroke from paraneoplastic syndrome in a pediatric patient with an intracranial mature teratoma: a case report

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Vasospasm and subsequent stroke from paraneoplastic syndrome in a pediatric patient with an intracranial mature teratoma: a case report

Jenson, Amanda V; Rizvi, Ali Yunus; Reynolds, Rebecca A; Hartnett-Wright, Sara; Gellar, Thomas J; Stapleton, Stacie; Gonzalez-Gomez, Ignacio; Akbari, S Hassan A; Smyth, Matthew D

Child's nervous system, 2024-May-31, 2024-05-31, 20240531

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Teratomas account for 18-20% of all intracranial germ cell tumors and mostly occur in the pineal region with only a few cases of pediatric sellar and suprasellar teratomas described in the literature. Here, we present a case of a child with an intracranial mature teratoma with pancreatic features causing vasospasm and subsequent stroke, found to be positive for CDKN2A-an independent variant associated with malignancy and small vessel disease leading to stroke.

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