Hyperspectral images (HSIs) are often corrupted by a mixture of several types of noise during the acquisition process, e.g., Gaussian noise, impulse noise, dead lines, stripes, etc. Such complex noise could degrade the quality of the acquired HSIs, limiting the precision of the subsequent processing. In this paper, we present a novel tensor-based HSI restoration approach by fully identifying the intrinsic structures of the clean HSI part and the mixed noise part. Specifically, for the clean HSI part, we use tensor Tucker decomposition to describe the global correlation among all bands, and an anisotropic spatial-spectral total variation regularization to characterize the piecewise smooth structure in both spatial and spectral domains. For the mixed noise part, we adopt the ℓ 1 norm regularization to detect the sparse noise, including stripes, impulse noise, and dead pixels. Despite that TV regularization has the ability of removing Gaussian noise, the Frobenius norm term is further used to model heavy Gaussian noise for some real-world scenarios. Then, we develop an efficient algorithm for solving the resulting optimization problem by using the augmented Lagrange multiplier method. Finally, extensive experiments on simulated and real-world noisy HSIs are carried out to demonstrate the superiority of the proposed method over the existing state-of-the-art ones.