As part of the special issue on “The United Nations at Seventy-Five: Looking Back to Look Forward,” this essay looks at the UN's human rights efforts through the lens of the ethics of survival, normative ethics, the ethics of protection, institutional ethics, and the ethics of the human predicament in the face of the Sustainable Development Goals (SDGs). The essay finds that while the consecration of the right to life has made a contribution to the ethics of human survival, the overall impact of the human rights program has been marginal. Normative ethics shows the UN performing magisterially in drafting and adopting a body of international norms for the universal protection of human rights. However, when it comes to the ethics of protection, the UN performs poorly because of the numerous oppressive governments that control the world body. On the ethics of the human predicament, this essay finds that SDG 16, which is devoted to development, peace, justice, and strong institutions, has so far had little practical impact. Gross violations of human rights continue to take place in numerous parts of the world.