A SO2F2 mediated mild, practical, and gram-scale dehydroxylative transforming primary alcohols to quaternary ammonium salts

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A SO2F2 mediated mild, practical, and gram-scale dehydroxylative transforming primary alcohols to quaternary ammonium salts

Zhao, Chuang; Zha, Gao-Feng; Fang, Wan-Yin; Alharbi, Njud S.; Qin, Hua-Li

Tetrahedron, 08/2019, Volume: 75, Issue: 33

Journal Article

A simple, practical and gram-scale process for direct transformation of primary alcohols or silyl ethers to ammonium salts was developed. This method has the feathers of easy work-up (a simple filtration), mild condition, high yield, great practicality and robustness. And the application of the ammonium salts in Suzuki coupling reaction was also accomplished. Display omitted •A simple, practical and gram-scale process for direct transformation of alcohols or silyl ethers to ammonium salts.•Easy work-up (a simple filtration), mild condition, high yield, great practicality and robustness.•Application of the ammonium salts in Suzuki coupling reaction.

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Zhao, Chuang | Zha, Gao-Feng | Fang, Wan-Yin | Alharbi, Njud S. | Qin, Hua-Li

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