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de Bie, Roosmarie P., MD; Vergers-Spooren, Henke C., MD; Massuger, Leon F.A.G., MD, PhD; Siebers, Albertus G., PhD; Salet-van der Pol, Maria R.J; Vedder, Judith E.M; Melchers, Willem J.G., PhD; Bulten, Johan, MD, PhD; Bekkers, Ruud L.M., MD, PhD
American journal of obstetrics and gynecology, 07/2011, Volume: 205, Issue: 1Journal Article
Objective The objective of the study was to assess the screening history of women with cervical cancer and review normal cervical smears 5 years preceding the diagnosis. Study Design Cytological and histological results of 401 women treated for invasive cervical cancer between 1991 and 2008 at the Radboud University Nijmegen Medical Center were studied. Ninety-eight normal smears were reviewed. Results Of the 401 women, 269 (67%) received at least 1 invitation for the national screening program for cervical cancer (NCSP). One- third fell outside the target age of the NCSP. Seventeen percent never responded to the invitation(s). Twenty-one percent had 1 or more normal smears within 5 years preceding the diagnosis. After review, only 39% of those smears were reviewed as a normal smear. Conclusion Half of the women with cervical cancer were never screened because of the limited target age range or nonattendance. Twenty-one percent had a normal smear within 5 years preceding the diagnosis, caused by interpretation and/or sampling errors.
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