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Olczak, Andrzej; Pawlak, Tomasz; Kałużyńska, Sylwia; Gobis, Katarzyna; Korona-Głowniak, Izabela; Suśniak, Katarzyna; Zaborowski, Marcin; Szczesio, Małgorzata
International journal of molecular sciences, 02/2023, Volume: 24, Issue: 4Journal Article
Three new crystal structures of 1H-benzodimidazole derivatives were determined. In the structures of these compounds, an identical system of hydrogen bonds, C(4), was observed. Solid-state NMR was applied for testing the quality of the obtained samples. All of these compounds were tested for in vitro antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, as well as antifungal activity, by checking their selectivity. ADME calculations indicate that the compounds can be tested as potential drugs.
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