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Kaiser, Franziska K; de le Roi, Madeleine; Jo, Wendy K; Gerhauser, Ingo; Molnár, Viktor; Osterhaus, Albert D M E; Baumgärtner, Wolfgang; Ludlow, Martin
Viruses, 04/2023, Volume: 15, Issue: 5Journal Article
Skunk amdoparvovirus ( , SKAV) is closely related to Aleutian mink disease virus (AMDV) and circulates primarily in striped skunks ( ) in North America. SKAV poses a threat to mustelid species due to reported isolated infections of captive American mink ( ) in British Columbia, Canada. We detected SKAV in a captive striped skunk in a German zoo by metagenomic sequencing. The pathological findings are dominated by lymphoplasmacellular inflammation and reveal similarities to its relative , the causative agent of Aleutian mink disease. Phylogenetic analysis of the whole genome demonstrated 94.80% nucleotide sequence identity to a sequence from Ontario, Canada. This study is the first case description of a SKAV infection outside of North America.
