Purpose/Significance Open science is shaping a new academic innovation ecology, aiming to promote open exchange and use of knowledge, emphasize open and cooperative research methods, and thus accelerate scientific innovation. Open innovation emphasizes the flow of knowledge across organizational boundaries. Both of them have obvious internal consistency and regard the free flow of knowledge as the driving factor of innovation. However, there are few studies on the relationship between open science and open innovation at present. They are often studied separately in the scientific research environment and the enterprise environment, ignoring the common role and integration of the two in the open innovation ecology. This paper aims to analyze the consistency of the connotation of open science and open innovation, study the mechanism of open science for innovation ecology, and provide reference for building an open science innovation ecology integrating open science and open innovation, as well as for developi