We experimentally study the occurrence of pattern formation during the slot-die coating of low-viscosity nearly Newtonian liquids onto Polyethylenterephthalat (PET)-substrates. In particular, it is demonstrated that with increase of the coating speed a homogeneous coating becomes unstable with respect to periodic stripe patterns. Thereby, depending on the liquid viscosity, the stripes can be oriented parallel or perpendicular with respect to the coating direction. Mixed states do also occur. The spatial period of perpendicular parallel stripes increases decrease with the coating speed. The dependence of the effect on various control parameters is investigated. Finally, a simple theoretical model based on the hydrodynamics of thin films of partially wetting liquids is analyzed. Comparing the results to the experiments, conclusions are drawn regarding the acting instability and pattern formation mechanisms.