Brief report on the HMGB1-antagonism exerted by glycyrrhizin could be fruitful against COVID-19

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Brief report on the HMGB1-antagonism exerted by glycyrrhizin could be fruitful against COVID-19

Ciprandi, Giorgio; Bellussi, Luisa Maria; Damiani, Valerio; Passali, Desiderio

Acta bio-medica de l'Ateneo Parmense, 10/2021, Volume: 92, Issue: Suppl 6

Journal Article

The COVID-19 pandemic era is causing a relevant issue for the health. There is no specific drug able to antagonize the SARS-CoV-2 infection. As a consequence, there is growing interest about potential molecules able to contrast infection. In this regard, HMGB, an alarmin, may play a relevant role in pathogenic mechanisms induced by SARS-CoV-2. As HMGB1 is antagonized by glycyrrhizin, this substance could be potentially useful as ancillary treatment in COVID-19. ( www.actabiomedica.it )

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Ciprandi, Giorgio | Bellussi, Luisa Maria | Damiani, Valerio | Passali, Desiderio

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