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  • Neuropathies: DPN, HIV, Idi...
    Ulane, Christina M.; Brannagan, Thomas H.

    Managing Pain, 03/2013
    Book Chapter

    Neuropathic pain poses a significant epidemiological, social and financial burden, as approximately 10% of the population suffers from neuropathic pain. Neuropathic pain can be distinguished from mechanical or nociceptive pain by its qualities, distribution, and in some cases, diagnostic testing. There are currently over 200 known causes of peripheral neuropathy, with diabetes being the most common. However, in up to 40% of individuals no identifiable cause can be found. In this chapter, the different types, mechanisms, workup and etiology, categorization (e.g. focal or diffuse, large or small fiber), and treatment of neuropathic pain are discussed.