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Petersen, Nils H.
Neurocritical care, 10/2020, Volume: 33, Issue: 2Journal Article
In this issue of the Neurocritical Care, the authors submit an innovative analysis showing that early aggressive reduction in systolic blood pressure is associated with increased mortality and worse in-hospital outcome after intracerebral hemorrhage (ICH) 1. Furthermore, the majority of subjects in the Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH-II) and the Implementation of Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT-2) had small- to moderate-sized hematomas in subcortical locations, leaving those with large and more severe hemorrhages an understudied population. ...characterizing patients that are likely to benefit remains crucial, and the interaction between timing, intensity, and duration of different BP interventions and outcome requires further definition. Information on blood pressure management or the use of antihypertensive medication is not available, and treatment practices likely varied across centers and during the extended timeframe of data collection.
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