Faecal microbiota transplantation for eradication of co-infection with Clostridioides difficile and extensively drug-resistant KPC-producing Klebsiella pneumoniae

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Faecal microbiota transplantation for eradication of co-infection with Clostridioides difficile and extensively drug-resistant KPC-producing Klebsiella pneumoniae

Bahl, Martin Iain; Jørgensen, Simon Mark Dahl; Skriver, Alberte Hjortgård; Larsen, Nanna Alsig; Wang, Mikala; Licht, Tine Rask; Dahlerup, Jens Frederik; Hvas, Christian Lodberg

Scandinavian journal of gastroenterology, 05/2020, Volume: 55, Issue: 5

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infection may be complicated by co-infection with other pathogens. We here describe the successful use of faecal microbiota transplantation to eradicate concomitant and extensively drug-resistant (XDR) KPC-producing Donor microbiota efficiently engrafted in the patient, and a donor-like microbial assemblage persisted in the patient during six months follow-up. The report explores the potential for the donor microbiota to eradicate and replace multi-resistant microorganisms.

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